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Use of Psychotropic Drug Urine Test Strips in Opiate Maintenance Therapy: A Clinical Assessment of its Advantages

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Název: Use of Psychotropic Drug Urine Test Strips in Opiate Maintenance Therapy: A Clinical Assessment of its Advantages
Autoři: Victorri-Vigneau, Caroline, Rousselet, Morgane, Grall-Bronnec, Marie, Bouquié, Régis, Belliot, Emeric, Guerlais, Marylène, Guillet, Jean-Yves, Jolliet, Pascale
Přispěvatelé: Bruere, Gérard, Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes), Service de Pharmacologie Clinique CHU Nantes, MethodS in Patients-centered outcomes and HEalth ResEarch (SPHERE), Université de Tours (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Nantes - UFR des Sciences Pharmaceutiques et Biologiques, Université de Nantes (UN)-Université de Nantes (UN), Centre for Evaluation and Information on Pharmacodependence Nantes, Clinical Pharmacology Department Nantes, Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes)-Centre Hospitalier Universitaire de Nantes = Nantes University Hospital (CHU Nantes), Biostatistique, Recherche Clinique et Mesures Subjectives en Santé (EA 4275), Université de Nantes - UFR des Sciences Pharmaceutiques et Biologiques
Zdroj: Substance Abuse. 37:584-590
Informace o vydavateli: SAGE Publications, 2016.
Rok vydání: 2016
Témata: [SDV]Life Sciences [q-bio], Opioid, Drug Prescriptions, Buprenorphine, opiate maintenance treatment, methadone, 03 medical and health sciences, Drug Prescriptions/*statistics & numerical data, 0302 clinical medicine, Psychotropic Drugs/*urine, Opiate Substitution Treatment/*methods, Opiate Substitution Treatment, Humans, Buprenorphine/therapeutic use, Analgesics, Psychotropic Drugs, opiate dependence, 6. Clean water, 3. Good health, [SDV] Life Sciences [q-bio], Analgesics, Opioid, Methadone/therapeutic use, urine test strips, Opioid/therapeutic use, Methadone
Popis: Background: Methadone and buprenorphine are the 2 opiate maintenance treatments (OMTs) available in France. According to good clinical practices, a full clinical and biological assessment is required before deciding to initiate or renew an OMT. For methadone, this assessment includes psychoactive drug consumption investigation through an initial interview completed by a systematic urine test mandatory before starting methadone treatment. In case of buprenorphine prescription, the situation is less clear and the urine test was not systematically performed. This work aims at evaluating changes in the therapeutic strategy brought by the systematic use of urine strips for detecting drug consumptions. Methods: During 1 month, for each case of OMT renewal, physicians belonging to the 3 types of prescribing structures in France (general medicine, specialized centers for drug addict patients, and specialized centers for drug addict patients in prison) had to complete a specific questionnaire about prescription renewal. This questionnaire contained 2 parts. The first part was completed by the physicians before the urine test strip realization. The second part was completed by the same physicians at the end of the consultation, after obtaining the results from the urine test strip. A change between parts 1 and 2 of the questionnaire concerning OMT prescription, dialogue with the patient, associated psychotropic drug prescription, and orientation were considered as a change in therapeutic strategy. Results: A total of 429 questionnaires have been collected. Among them, 315 showed at least 1 change in therapeutic strategy (73.4%). Conclusions: This study highlighted the important benefits brought by the urine test strip in managing patients under opiate maintenance treatment. Urine test strips provided an immediate answer that allowed physicians to optimize their therapeutic strategy. However, regulatory evolutions would be necessary to ease their implantation.
Druh dokumentu: Article
Jazyk: English
ISSN: 1547-0164
0889-7077
DOI: 10.1080/08897077.2016.1176979
Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/27093305
https://pubmed.ncbi.nlm.nih.gov/27093305/
https://www.ncbi.nlm.nih.gov/pubmed/27093305
https://www.tandfonline.com/doi/full/10.1080/08897077.2016.1176979
https://hal.science/hal-03157758v1
https://doi.org/10.1080/08897077.2016.1176979
Rights: URL: https://journals.sagepub.com/page/policies/text-and-data-mining-license
Přístupové číslo: edsair.doi.dedup.....ed4489a19d0fa3b000482fa476856da6
Databáze: OpenAIRE
Popis
Abstrakt:Background: Methadone and buprenorphine are the 2 opiate maintenance treatments (OMTs) available in France. According to good clinical practices, a full clinical and biological assessment is required before deciding to initiate or renew an OMT. For methadone, this assessment includes psychoactive drug consumption investigation through an initial interview completed by a systematic urine test mandatory before starting methadone treatment. In case of buprenorphine prescription, the situation is less clear and the urine test was not systematically performed. This work aims at evaluating changes in the therapeutic strategy brought by the systematic use of urine strips for detecting drug consumptions. Methods: During 1 month, for each case of OMT renewal, physicians belonging to the 3 types of prescribing structures in France (general medicine, specialized centers for drug addict patients, and specialized centers for drug addict patients in prison) had to complete a specific questionnaire about prescription renewal. This questionnaire contained 2 parts. The first part was completed by the physicians before the urine test strip realization. The second part was completed by the same physicians at the end of the consultation, after obtaining the results from the urine test strip. A change between parts 1 and 2 of the questionnaire concerning OMT prescription, dialogue with the patient, associated psychotropic drug prescription, and orientation were considered as a change in therapeutic strategy. Results: A total of 429 questionnaires have been collected. Among them, 315 showed at least 1 change in therapeutic strategy (73.4%). Conclusions: This study highlighted the important benefits brought by the urine test strip in managing patients under opiate maintenance treatment. Urine test strips provided an immediate answer that allowed physicians to optimize their therapeutic strategy. However, regulatory evolutions would be necessary to ease their implantation.
ISSN:15470164
08897077
DOI:10.1080/08897077.2016.1176979