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Model projections on the impact of HCV treatment in the prevention of HCV transmission among people who inject drugs in Europe

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Titel:	Model projections on the impact of HCV treatment in the prevention of HCV transmission among people who inject drugs in Europe
Autoren:	Martin Kåberg, Jens Reimer, Natasha K. Martin, Marie Jauffret-Roustide, Anne Øvrehus, John F. Dillon, Maria Prins, Geert Robaeys, Henrikki Brummer-Korvenkontio, Olav Dalgard, Daniela K van Santen, Viktor Mravčík, Matthew Hickman, Håvard Midgard, Peter Vickerman, David J. Goldberg, Sharon J. Hutchinson, Mojca Matičič, Patrizia Carrieri, Hannah Fraser, Amy Matser, Bernd Schulte, Ruth Zimmermann
Weitere Verfasser:	DUFOUR, Jean-Charles
Quelle:	Fraser, H, Martin, N, Brummer-Korvenkontio, H, Carrieri, P, Dalgard, O, Dillon, J, Goldberg, D, Hutchinson, S, Jauffret-Roustide, M, Kaberg, M, Matser, A, Matičič, M, Midgard, H, Mravčík, V, Øvrehus, A, Prins, M, Reimer, J, Robaeys, G, Schulte, B, van Santen, D, Zimmermann, R, Vickerman, P & Hickman, M 2018, 'Model projections on the impact of HCV treatment in the prevention of HCV transmission among people who inject drugs in Europe', Journal of Hepatology, vol. 68, no. 3, pp. 402-411. https://doi.org/10.1016/j.jhep.2017.10.010 Fraser, H, Martin, N K, Brummer-Korvenkontio, H, Carrieri, P, Dalgard, O, Dillon, J, Goldberg, D, Hutchinson, S, Jauffret-Roustide, M, Kåberg, M, Matser, A A, Matičič, M, Midgard, H, Mravcik, V, Øvrehus, A, Prins, M, Reimer, J, Robaeys, G, Schulte, B, van Santen, D K, Zimmermann, R, Vickerman, P & Hickman, M 2018, ' Model projections on the impact of HCV treatment in the prevention of HCV transmission among people who inject drugs in Europe ', Journal of Hepatology, vol. 68, no. 3, pp. 402-411 . https://doi.org/10.1016/j.jhep.2017.10.010
Verlagsinformationen:	Elsevier BV, 2018.
Publikationsjahr:	2018
Schlagwörter:	Direct-acting antivirals, Hepatitis C, PWID, Opioid substitution therapy, Chronic/drug therapy, Antiviral Agents, Europe/epidemiology, HCV transmission, Hepatitis C, Chronic/drug therapy, Intravenous/complications, Theoretical, Disease Transmission, SDG 3 - Good Health and Well-being, Models, Needle-Exchange Programs/methods, Opiate Substitution Treatment/methods, Journal Article, Disease Transmission, Infectious, Opiate Substitution Treatment, Prevalence, Humans, Disease Transmission, Infectious/prevention & control, Substance Abuse, Intravenous, Substance Abuse, Intravenous/complications, injecting drug users, Antiviral Agents/therapeutic use, Hepatology, Incidence, Substance Abuse, Hepatitis C, Chronic, Models, Theoretical, Infectious/prevention & control, name=Hepatology, 3. Good health, [SDV] Life Sciences [q-bio], Europe, Needle-Exchange Programs, HCV treatment, Needs Assessment
Beschreibung:	Prevention of hepatitis C virus (HCV) transmission among people who inject drugs (PWID) is critical for eliminating HCV in Europe. We estimated the impact of current and scaled-up HCV treatment with and without scaling up opioid substitution therapy (OST) and needle and syringe programmes (NSPs) across Europe over the next 10 years.We collected data on PWID HCV treatment rates, PWID prevalence, HCV prevalence, OST, and NSP coverage from 11 European settings. We parameterised an HCV transmission model to setting-specific data that project chronic HCV prevalence and incidence among PWID.At baseline, chronic HCV prevalence varied from 55% (Finland/Sweden), and
Publikationsart:	Article
Dateibeschreibung:	application/pdf
Sprache:	English
ISSN:	0168-8278
DOI:	10.1016/j.jhep.2017.10.010
Zugangs-URL:	http://www.journal-of-hepatology.eu/article/S0168827817323875/pdf https://pubmed.ncbi.nlm.nih.gov/29080808 https://europepmc.org/article/MED/29080808 https://research-information.bris.ac.uk/en/publications/model-projections-on-the-impact-of-hcv-treatment-in-the-prevention-of-hcv-transmission-among-people-who-inject-drugs-in-europe(d0cfcb46-1f31-44b6-b5b6-41abc5e2cb64).html https://www.sciencedirect.com/science/article/pii/S0168827817323875 https://www.narcis.nl/publication/RecordID/oai%3Apure.amc.nl%3Apublications%2F92e76221-cec9-415d-8303-83a262379410 https://researchinformation.amsterdamumc.org/en/publications/model-projections-on-the-impact-of-hcv-treatment-in-the-preventio http://findresearcher.sdu.dk/portal/files/137608769/Model_projections_on_the_impact_of_HCV_treatment_in_the_prevention_of_HCV_transmission_among_people_who_inject_drugs_in_Europe.pdf https://amu.hal.science/hal-02146845v1 https://doi.org/10.1016/j.jhep.2017.10.010 https://hdl.handle.net/1983/d0cfcb46-1f31-44b6-b5b6-41abc5e2cb64 https://research-information.bris.ac.uk/ws/files/135274719/dipp_manuscript_revised2.pdf https://findresearcher.sdu.dk:8443/ws/files/137608769/Model_projections_on_the_impact_of_HCV_treatment_in_the_prevention_of_HCV_transmission_among_people_who_inject_drugs_in_Europe.pdf http://hdl.handle.net/1942/27320
Rights:	CC BY NC ND
Dokumentencode:	edsair.doi.dedup.....ea756d10b6f89a0f5b8beaecc8739e57
Datenbank:	OpenAIRE

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Beschreibung
Abstract:	Prevention of hepatitis C virus (HCV) transmission among people who inject drugs (PWID) is critical for eliminating HCV in Europe. We estimated the impact of current and scaled-up HCV treatment with and without scaling up opioid substitution therapy (OST) and needle and syringe programmes (NSPs) across Europe over the next 10 years.We collected data on PWID HCV treatment rates, PWID prevalence, HCV prevalence, OST, and NSP coverage from 11 European settings. We parameterised an HCV transmission model to setting-specific data that project chronic HCV prevalence and incidence among PWID.At baseline, chronic HCV prevalence varied from 55% (Finland/Sweden), and
ISSN:	01688278
DOI:	10.1016/j.jhep.2017.10.010