A new anti-microbial combination prolongs the latency period, reduces acute histologic chorioamnionitis as well as funisitis, and improves neonatal outcomes in preterm PROM
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| Názov: | A new anti-microbial combination prolongs the latency period, reduces acute histologic chorioamnionitis as well as funisitis, and improves neonatal outcomes in preterm PROM |
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| Autori: | Chan-Wook Park, Piya Chaemsaithong, Jong Kwan Jun, Joong Shin Park, Sun Min Kim, Roberto Romero, Bo Hyun Yoon, JoonHo Lee |
| Prispievatelia: | College of Medicine, Dept. of Obstetrics & Gynecology, JoonHo Lee, Roberto Romero, Sun Min Kim, Piya Chaemsaithong, Chan-Wook Park, Joong Shin Park, Jong Kwan Jun, Bo Hyun Yoon, Lee, Joon Ho |
| Zdroj: | The Journal of Maternal-Fetal & Neonatal Medicine. 29:707-720 |
| Informácie o vydavateľovi: | Informa UK Limited, 2015. |
| Rok vydania: | 2015 |
| Predmety: | Adult, Fetal Membranes, Premature Rupture, Time Factors, intra-ventricular hemorrhage, Pregnancy Outcome*/epidemiology, Obstetric Labor, 03 medical and health sciences, Chorioamnionitis/drug therapy, metronidazole, Obstetric Labor, Premature, 0302 clinical medicine, Anti-Bacterial Agents/administration & dosage, Drug Therapy, Pregnancy, Chorioamnionitis/epidemiology, Clarithromycin, Metronidazole, Humans, Pregnancy Complications, Infectious, Fetal Membranes, Retrospective Studies, cerebral palsy, Ceftriaxone, Infant, Newborn, Pregnancy Outcome, Infant, preterm birth, Premature Rupture/epidemiology, Newborn, clarithromycin, Clarithromycin/administration & dosage, Premature Rupture/drug therapy, Anti-Bacterial Agents, 3. Good health, Pregnancy Complications, Premature/drug therapy, Chorioamnionitis, Ceftriaxone/administration & dosage, Infectious/epidemiology, Combination, Metronidazole/administration & dosage, Drug Therapy, Combination, Female, intra-amniotic inflammation, Infectious/drug therapy, intra-amniotic infection, Premature/epidemiology |
| Popis: | Antibiotic administration is a standard practice in preterm premature rupture of membranes (PROM). Specific anti-microbial agents often include ampicillin and/or erythromycin. Anaerobes and genital mycoplasmas are frequently involved in preterm PROM, but are not adequately covered by antibiotics routinely used in clinical practice. Our objective was to compare outcomes of PROM treated with standard antibiotic administration versus a new combination more effective against these bacteria.A retrospective study compared perinatal outcomes in 314 patients with PROM 23 ng/mL).(1) Patients treated with regimen 2 had a longer median antibiotic-to-delivery interval than those with regimen 1 [median (interquartile range) 23 d (10-51 d) versus 12 d (5-52 d), p |
| Druh dokumentu: | Article |
| Jazyk: | English |
| ISSN: | 1476-4954 1476-7058 |
| DOI: | 10.3109/14767058.2015.1020293 |
| Prístupová URL adresa: | https://www.tandfonline.com/doi/pdf/10.3109/14767058.2015.1020293?needAccess=true https://pubmed.ncbi.nlm.nih.gov/26373262 https://www.tandfonline.com/doi/pdf/10.3109/14767058.2015.1020293 https://www.tandfonline.com/doi/full/10.3109/14767058.2015.1020293 https://yonsei.pure.elsevier.com/en/publications/a-new-anti-microbial-combination-prolongs-the-latency-period-redu https://pubmed.ncbi.nlm.nih.gov/26373262/ https://europepmc.org/article/MED/26373262 https://snucm.elsevierpure.com/en/publications/a-new-anti-microbial-combination-prolongs-the-latency-period-redu |
| Rights: | CC BY NC ND |
| Prístupové číslo: | edsair.doi.dedup.....e5486c8f06d202ac4662965edaa985bc |
| Databáza: | OpenAIRE |
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Nájsť tento článok vo Web of Science | Abstrakt: | Antibiotic administration is a standard practice in preterm premature rupture of membranes (PROM). Specific anti-microbial agents often include ampicillin and/or erythromycin. Anaerobes and genital mycoplasmas are frequently involved in preterm PROM, but are not adequately covered by antibiotics routinely used in clinical practice. Our objective was to compare outcomes of PROM treated with standard antibiotic administration versus a new combination more effective against these bacteria.A retrospective study compared perinatal outcomes in 314 patients with PROM 23 ng/mL).(1) Patients treated with regimen 2 had a longer median antibiotic-to-delivery interval than those with regimen 1 [median (interquartile range) 23 d (10-51 d) versus 12 d (5-52 d), p |
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| ISSN: | 14764954 14767058 |
| DOI: | 10.3109/14767058.2015.1020293 |