Intra-Operative Hypotension is a Risk Factor for Post-operative Silent Brain Ischaemia in Patients With Pre-operative Hypertension Undergoing Carotid Endarterectomy

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Titel: Intra-Operative Hypotension is a Risk Factor for Post-operative Silent Brain Ischaemia in Patients With Pre-operative Hypertension Undergoing Carotid Endarterectomy
Autoren: Rots, Marjolijn L, Fassaert, Leonie M M, Kappelle, L Jaap, de Groot, Mark C H, Haitjema, Saskia, Bonati, Leo H, van Klei, Wilton A, de Borst, Gert J
Weitere Verfasser: Zorgeenheid Vaatchirurgie Medisch, ZL Cerebrovasculaire Ziekten Medisch, Brain, Circulatory Health, CDL Upod, Other research (not in main researchprogram), CDL Arcadia, Management Vitale Functies, Medische staf Anesthesiologie, Regenerative Medicine and Stem Cells
Quelle: European Journal of Vascular and Endovascular Surgery. 59:526-534
Verlagsinformationen: Elsevier BV, 2020.
Publikationsjahr: 2020
Schlagwörter: Brain Infarction, Male, Asymptomatic Diseases/epidemiology, Postoperative Complications/diagnostic imaging, Brain/blood supply, Brain Infarction/diagnostic imaging, 03 medical and health sciences, Hypertension/complications, Postoperative Complications, 0302 clinical medicine, Carotid endarterectomy, Risk Factors, Ischaemic brain lesions, Intra-operative monitoring, Intraoperative Complications/diagnosis, Journal Article, Humans, Carotid Stenosis, Hypotension/diagnosis, Prospective Studies, Intraoperative Complications, Blood Pressure Determination/statistics & numerical data, Aged, Retrospective Studies, Endarterectomy, Carotid, Brain, Diffusion weighted imaging, Blood Pressure Determination, Middle Aged, Treatment Outcome, Diffusion Magnetic Resonance Imaging, Asymptomatic Diseases, Hypertension, Preoperative Period, Blood pressure, Carotid Stenosis/complications, Endarterectomy, Carotid/adverse effects, Surgery, Female, Hypotension, Cardiology and Cardiovascular Medicine
Beschreibung: Intra-operative haemodynamic instability during carotid endarterectomy (CEA) has been associated with an increased risk of procedural stroke. Diffusion weighted imaging (DWI) lesions have been proposed as a surrogate marker for peri-operative silent cerebral ischaemia. This study aimed to investigate the relationship between peri-operative blood pressure (BP) and presence of post-operative DWI lesions in patients undergoing CEA.A retrospective analysis was performed based on patients with symptomatic CEA included in the MRI substudy of the International Carotid Stenting Study. Relative intra-operative hypotension was defined as a decrease of intra-operative systolic BP ≥ 20% compared with pre-operative ('baseline') BP, absolute hypotension was defined as a drop in systolic BP
Publikationsart: Article
Dateibeschreibung: application/pdf
Sprache: English
ISSN: 1078-5884
DOI: 10.1016/j.ejvs.2020.01.007
Zugangs-URL: http://www.ejves.com/article/S1078588420300526/pdf
https://pubmed.ncbi.nlm.nih.gov/32033871
https://pubmed.ncbi.nlm.nih.gov/32033871/
https://www.sciencedirect.com/science/article/pii/S1078588420300526
https://www.sciencedirect.com/science/article/abs/pii/S1078588420300526
https://www.ncbi.nlm.nih.gov/pubmed/32033871
https://europepmc.org/article/MED/32033871
https://dspace.library.uu.nl/handle/1874/439372
Rights: Elsevier Non-Commercial
Dokumentencode: edsair.doi.dedup.....dd5dd1a8ae67e54dd6d2ea8910ea9504
Datenbank: OpenAIRE
Beschreibung
Abstract:Intra-operative haemodynamic instability during carotid endarterectomy (CEA) has been associated with an increased risk of procedural stroke. Diffusion weighted imaging (DWI) lesions have been proposed as a surrogate marker for peri-operative silent cerebral ischaemia. This study aimed to investigate the relationship between peri-operative blood pressure (BP) and presence of post-operative DWI lesions in patients undergoing CEA.A retrospective analysis was performed based on patients with symptomatic CEA included in the MRI substudy of the International Carotid Stenting Study. Relative intra-operative hypotension was defined as a decrease of intra-operative systolic BP ≥ 20% compared with pre-operative ('baseline') BP, absolute hypotension was defined as a drop in systolic BP
ISSN:10785884
DOI:10.1016/j.ejvs.2020.01.007