Intra-Operative Hypotension is a Risk Factor for Post-operative Silent Brain Ischaemia in Patients With Pre-operative Hypertension Undergoing Carotid Endarterectomy
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| Titel: | Intra-Operative Hypotension is a Risk Factor for Post-operative Silent Brain Ischaemia in Patients With Pre-operative Hypertension Undergoing Carotid Endarterectomy |
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| Autoren: | Rots, Marjolijn L, Fassaert, Leonie M M, Kappelle, L Jaap, de Groot, Mark C H, Haitjema, Saskia, Bonati, Leo H, van Klei, Wilton A, de Borst, Gert J |
| Weitere Verfasser: | Zorgeenheid Vaatchirurgie Medisch, ZL Cerebrovasculaire Ziekten Medisch, Brain, Circulatory Health, CDL Upod, Other research (not in main researchprogram), CDL Arcadia, Management Vitale Functies, Medische staf Anesthesiologie, Regenerative Medicine and Stem Cells |
| Quelle: | European Journal of Vascular and Endovascular Surgery. 59:526-534 |
| Verlagsinformationen: | Elsevier BV, 2020. |
| Publikationsjahr: | 2020 |
| Schlagwörter: | Brain Infarction, Male, Asymptomatic Diseases/epidemiology, Postoperative Complications/diagnostic imaging, Brain/blood supply, Brain Infarction/diagnostic imaging, 03 medical and health sciences, Hypertension/complications, Postoperative Complications, 0302 clinical medicine, Carotid endarterectomy, Risk Factors, Ischaemic brain lesions, Intra-operative monitoring, Intraoperative Complications/diagnosis, Journal Article, Humans, Carotid Stenosis, Hypotension/diagnosis, Prospective Studies, Intraoperative Complications, Blood Pressure Determination/statistics & numerical data, Aged, Retrospective Studies, Endarterectomy, Carotid, Brain, Diffusion weighted imaging, Blood Pressure Determination, Middle Aged, Treatment Outcome, Diffusion Magnetic Resonance Imaging, Asymptomatic Diseases, Hypertension, Preoperative Period, Blood pressure, Carotid Stenosis/complications, Endarterectomy, Carotid/adverse effects, Surgery, Female, Hypotension, Cardiology and Cardiovascular Medicine |
| Beschreibung: | Intra-operative haemodynamic instability during carotid endarterectomy (CEA) has been associated with an increased risk of procedural stroke. Diffusion weighted imaging (DWI) lesions have been proposed as a surrogate marker for peri-operative silent cerebral ischaemia. This study aimed to investigate the relationship between peri-operative blood pressure (BP) and presence of post-operative DWI lesions in patients undergoing CEA.A retrospective analysis was performed based on patients with symptomatic CEA included in the MRI substudy of the International Carotid Stenting Study. Relative intra-operative hypotension was defined as a decrease of intra-operative systolic BP ≥ 20% compared with pre-operative ('baseline') BP, absolute hypotension was defined as a drop in systolic BP |
| Publikationsart: | Article |
| Dateibeschreibung: | application/pdf |
| Sprache: | English |
| ISSN: | 1078-5884 |
| DOI: | 10.1016/j.ejvs.2020.01.007 |
| Zugangs-URL: | http://www.ejves.com/article/S1078588420300526/pdf https://pubmed.ncbi.nlm.nih.gov/32033871 https://pubmed.ncbi.nlm.nih.gov/32033871/ https://www.sciencedirect.com/science/article/pii/S1078588420300526 https://www.sciencedirect.com/science/article/abs/pii/S1078588420300526 https://www.ncbi.nlm.nih.gov/pubmed/32033871 https://europepmc.org/article/MED/32033871 https://dspace.library.uu.nl/handle/1874/439372 |
| Rights: | Elsevier Non-Commercial |
| Dokumentencode: | edsair.doi.dedup.....dd5dd1a8ae67e54dd6d2ea8910ea9504 |
| Datenbank: | OpenAIRE |
| Abstract: | Intra-operative haemodynamic instability during carotid endarterectomy (CEA) has been associated with an increased risk of procedural stroke. Diffusion weighted imaging (DWI) lesions have been proposed as a surrogate marker for peri-operative silent cerebral ischaemia. This study aimed to investigate the relationship between peri-operative blood pressure (BP) and presence of post-operative DWI lesions in patients undergoing CEA.A retrospective analysis was performed based on patients with symptomatic CEA included in the MRI substudy of the International Carotid Stenting Study. Relative intra-operative hypotension was defined as a decrease of intra-operative systolic BP ≥ 20% compared with pre-operative ('baseline') BP, absolute hypotension was defined as a drop in systolic BP |
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| ISSN: | 10785884 |
| DOI: | 10.1016/j.ejvs.2020.01.007 |
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