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Predictors of Ventriculostomy-Associated Infections: A Retrospective Study of 243 Patients

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Title: Predictors of Ventriculostomy-Associated Infections: A Retrospective Study of 243 Patients
Authors: Junhyung Kim, Jae Ho Kim, Woosung Lee, Hyun Jin Han, Keun Young Park, Joonho Chung, Yong Bae Kim, Jin Yang Joo, Sang Kyu Park
Contributors: Junhyung Kim, Jae Ho Kim, Woosung Lee, Hyun Jin Han, Keun Young Park, Joonho Chung, Yong Bae Kim, Jin Yang Joo, Sang Kyu Park, Kim, Yong Bae
Source: World Neurosurgery. 160:e40-e48
Publisher Information: Elsevier BV, 2022.
Publication Year: 2022
Subject Terms: Catheters, Adolescent, External ventricular drainage, Catheter-Related Infections* / etiology, Ventriculostomy, 3. Good health, Drainage / adverse effects, Drainage / methods, VAI, 03 medical and health sciences, Ventriculostomy* / adverse effects, Cerebrospinal fluid, 0302 clinical medicine, Risk Factors, Catheter-Related Infections, Drainage, Humans, Infection, Catheter-Related Infections* / epidemiology, Retrospective Studies
Description: Risk factors of ventriculostomy-associated infection (VAI) reported in the literature are variable owing to heterogeneity of external ventricular drainage (EVD) procedures and management. This study aimed to assess the rate of VAI and its risk factors.The medical records of patients >18 years old who received EVD catheterizations between January 2015 and December 2020 were retrospectively reviewed.Among 243 patients with 355 catheters, 23 VAIs were identified, yielding VIA rates of 9.5% per patient and 6.5% per catheter. VAI was associated with a longer total EVD duration (29.2 days vs. 15.8 days, P < 0.001), a longer procedural time (72 minutes vs. 41 minutes, P < 0.001), intraoperative ventriculostomy (39.1% vs. 9.1%, P < 0.001), craniotomy (87.0% vs. 60.9%, P = 0.014), and other systemic infections (30.4% vs. 8.2%, P = 0.004). On multivariate analysis, a longer total EVD duration (odds ratio 1.086, P < 0.001), intraoperative ventriculostomy (odds ratio 6.119, P = 0.001), and other systemic infections (odds ratio 4.620, P = 0.015) were associated with VAI. There was no statistical difference between the VAI rates of patients with and without prophylactic EVD exchanges at a mean 12.6 days (7.1% vs. 2.2%, P = 0.401).Intraoperative ventriculostomy was independently associated with VAI. Prophylactic EVD exchange at 12.6 days did not lower VAI rate.
Document Type: Article
Language: English
ISSN: 1878-8750
DOI: 10.1016/j.wneu.2021.12.085
Access URL: https://pubmed.ncbi.nlm.nih.gov/34971831
Rights: Elsevier TDM
CC BY NC ND
Accession Number: edsair.doi.dedup.....dcd7027566ac747db86c731cd23fa0f8
Database: OpenAIRE
Description
Abstract:Risk factors of ventriculostomy-associated infection (VAI) reported in the literature are variable owing to heterogeneity of external ventricular drainage (EVD) procedures and management. This study aimed to assess the rate of VAI and its risk factors.The medical records of patients >18 years old who received EVD catheterizations between January 2015 and December 2020 were retrospectively reviewed.Among 243 patients with 355 catheters, 23 VAIs were identified, yielding VIA rates of 9.5% per patient and 6.5% per catheter. VAI was associated with a longer total EVD duration (29.2 days vs. 15.8 days, P < 0.001), a longer procedural time (72 minutes vs. 41 minutes, P < 0.001), intraoperative ventriculostomy (39.1% vs. 9.1%, P < 0.001), craniotomy (87.0% vs. 60.9%, P = 0.014), and other systemic infections (30.4% vs. 8.2%, P = 0.004). On multivariate analysis, a longer total EVD duration (odds ratio 1.086, P < 0.001), intraoperative ventriculostomy (odds ratio 6.119, P = 0.001), and other systemic infections (odds ratio 4.620, P = 0.015) were associated with VAI. There was no statistical difference between the VAI rates of patients with and without prophylactic EVD exchanges at a mean 12.6 days (7.1% vs. 2.2%, P = 0.401).Intraoperative ventriculostomy was independently associated with VAI. Prophylactic EVD exchange at 12.6 days did not lower VAI rate.
ISSN:18788750
DOI:10.1016/j.wneu.2021.12.085