Cost-effectiveness Outcomes of the National Gastric Cancer Screening Program in South Korea
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| Titel: | Cost-effectiveness Outcomes of the National Gastric Cancer Screening Program in South Korea |
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| Autoren: | Eun Cheol Park, Mi Na Suh, Jae Kwan Jun, Moon Hae Kang, Eun Cho, Kui Son Choi |
| Weitere Verfasser: | Eun Cho, Moon Hae Kang, Kui Son Choi, MiNa Suh, Jae Kwan Jun, Eun-Cheol Park, Park, Eun Chul |
| Quelle: | Asian Pacific Journal of Cancer Prevention. 14:2533-2540 |
| Verlagsinformationen: | Asian Pacific Organization for Cancer Prevention, 2013. |
| Publikationsjahr: | 2013 |
| Schlagwörter: | Adult, Male, economic evaluation, National Health Programs, Cost, Cost-Benefit Analysis, Early Detection of Cancer/economics, 03 medical and health sciences, Stomach Neoplasms/diagnosis, Stomach Neoplasms/mortality, 0302 clinical medicine, Stomach Neoplasms, Republic of Korea, 80 and over, Humans, Early Detection of Cancer, Aged, Aged, 80 and over, Korea, Middle Aged, Prognosis, gastric cancer screening, 3. Good health, Survival Rate, effectiveness analysis, stomach neoplasm, Early Detection of Cancer/mortality, Female, Stomach Neoplasms/economics, Quality-Adjusted Life Years, Follow-Up Studies |
| Beschreibung: | Although screening is necessary where gastric cancer is particularly common in Asia, the performance outcomes of mass screening programs have remained unclear. This study was conducted to evaluate cost-effectiveness outcomes of the national cancer screening program (NCSP) for gastric cancer in South Korea.People aged 40 years or over during 2002-2003 (baseline) were the target population. Screening recipients and patients diagnosed with gastric cancers were identified using the NCSP and Korea Central Cancer Registry databases. Clinical outcomes were measured in terms of mortality and life-years saved (LYS) of gastric cancer patients during 7 years based on merged data from the Korean National Health Insurance Corporation and National Statistical Office. We considered direct, indirect, and productivity-loss costs associated with screening attendance. Incremental cost-effectiveness ratio (ICER) estimates were produced according to screening method, sex, and age group compared to non-screening.The age-adjusted ICER for survival was 260,201,000-371,011,000 Korean Won (KW; 1USD=1,088 KW) for the upper-gastrointestinal (UGI) tract over non-screening. Endoscopy ICERs were lower (119,099,000-178,700,000 KW/survival) than UGI. To increase 1 life-year, additional costs of approximately 14,466,000-15,014,000 KW and 8,817,000-9,755,000 KW were required for UGI and endoscopy, respectively. Endoscopy was the most cost-effective strategy for males and females. With regard to sensitivity analyses varying based on the upper age limit, endoscopy NCSP was dominant for both males and females. For males, an upper limit of age 75 or 80 years could be considered. ICER estimates for LYS indicate that the gastric cancer screening program in Korea is cost-effective.Endoscopy should be recommended as a first-line method in Korea because it is beneficial among the Korean population. |
| Publikationsart: | Article |
| Sprache: | English |
| ISSN: | 1513-7368 |
| DOI: | 10.7314/apjcp.2013.14.5.2533 |
| Zugangs-URL: | http://society.kisti.re.kr/sv/SV_svpsbs03V.do?method=download&cn1=JAKO201321251181185 https://pubmed.ncbi.nlm.nih.gov/23725170 https://www.ncbi.nlm.nih.gov/pubmed/23725170 http://www.koreascience.or.kr/article/ArticleFullRecord.jsp?cn=POCPA9_2013_v14n4_2533 https://europepmc.org/article/MED/23725170 http://koreascience.or.kr:80/article/JAKO201321251181185.pdf https://pubmed.ncbi.nlm.nih.gov/23725170/ https://mdanderson.elsevierpure.com/en/publications/cost-effectiveness-outcomes-of-the-national-gastric-cancer-screen |
| Rights: | CC BY CC BY NC ND |
| Dokumentencode: | edsair.doi.dedup.....d9806821e42c6957da65a11f1cc8d32b |
| Datenbank: | OpenAIRE |
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Nájsť tento článok vo Web of Science | Abstract: | Although screening is necessary where gastric cancer is particularly common in Asia, the performance outcomes of mass screening programs have remained unclear. This study was conducted to evaluate cost-effectiveness outcomes of the national cancer screening program (NCSP) for gastric cancer in South Korea.People aged 40 years or over during 2002-2003 (baseline) were the target population. Screening recipients and patients diagnosed with gastric cancers were identified using the NCSP and Korea Central Cancer Registry databases. Clinical outcomes were measured in terms of mortality and life-years saved (LYS) of gastric cancer patients during 7 years based on merged data from the Korean National Health Insurance Corporation and National Statistical Office. We considered direct, indirect, and productivity-loss costs associated with screening attendance. Incremental cost-effectiveness ratio (ICER) estimates were produced according to screening method, sex, and age group compared to non-screening.The age-adjusted ICER for survival was 260,201,000-371,011,000 Korean Won (KW; 1USD=1,088 KW) for the upper-gastrointestinal (UGI) tract over non-screening. Endoscopy ICERs were lower (119,099,000-178,700,000 KW/survival) than UGI. To increase 1 life-year, additional costs of approximately 14,466,000-15,014,000 KW and 8,817,000-9,755,000 KW were required for UGI and endoscopy, respectively. Endoscopy was the most cost-effective strategy for males and females. With regard to sensitivity analyses varying based on the upper age limit, endoscopy NCSP was dominant for both males and females. For males, an upper limit of age 75 or 80 years could be considered. ICER estimates for LYS indicate that the gastric cancer screening program in Korea is cost-effective.Endoscopy should be recommended as a first-line method in Korea because it is beneficial among the Korean population. |
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| ISSN: | 15137368 |
| DOI: | 10.7314/apjcp.2013.14.5.2533 |