Dual ligand functionalized pH-sensitive liposomes for metastatic breast cancer treatment: in vitro and in vivo assessment: in vitro and in vivo assessment
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| Title: | Dual ligand functionalized pH-sensitive liposomes for metastatic breast cancer treatment: in vitro and in vivo assessment: in vitro and in vivo assessment |
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| Authors: | Prashant Pandey, Dilip Kumar Arya, Anit Kumar, Ajeet Kaushik, Yogendra Kumar Mishra, P. S. Rajinikanth |
| Source: | Journal of Materials Chemistry B. 13:2682-2694 |
| Publisher Information: | Royal Society of Chemistry (RSC), 2025. |
| Publication Year: | 2025 |
| Subject Terms: | Folic Acid/chemistry, Breast Neoplasms, Antineoplastic Agents, Apoptosis, Drug Screening Assays, Ligands, Cell Proliferation/drug effects, Rats, Sprague-Dawley, Folic Acid, Breast Neoplasms/drug therapy, Cell Movement, Antineoplastic Agents/chemistry, Humans, Animals, Particle Size, Cell Proliferation, Apoptosis/drug effects, Antitumor, Hydrogen-Ion Concentration, Rats, Drug Liberation, Liposomes, Fluorouracil/pharmacology, MCF-7 Cells, Female, Sprague-Dawley, Fluorouracil, Drug Screening Assays, Antitumor, Liposomes/chemistry, Oligopeptides, Cell Survival/drug effects |
| Description: | This research demonstrates the design and development of a novel dual-targeting, pH-sensitive liposomal (pSL) formulation of 5-fluorouracil, i.e., (5-FU-iRGD-FA-pSL) to manage breast cancer. |
| Document Type: | Article |
| Language: | English |
| ISSN: | 2050-7518 2050-750X |
| DOI: | 10.1039/d4tb02570a |
| Access URL: | https://pubmed.ncbi.nlm.nih.gov/39841132 https://portal.findresearcher.sdu.dk/da/publications/10377c9f-8091-462f-9771-97b9a1cf3a66 https://doi.org/10.1039/d4tb02570a |
| Rights: | Royal Society of Chemistry Licence to Publish |
| Accession Number: | edsair.doi.dedup.....d080d066d5477e72c3bf0041daf76f18 |
| Database: | OpenAIRE |
Nájsť tento článok vo Web of Science | Abstract: | This research demonstrates the design and development of a novel dual-targeting, pH-sensitive liposomal (pSL) formulation of 5-fluorouracil, i.e., (5-FU-iRGD-FA-pSL) to manage breast cancer. |
|---|---|
| ISSN: | 20507518 2050750X |
| DOI: | 10.1039/d4tb02570a |