Assessment of the EarlyCDT‐Lung test as an early biomarker of lung cancer in ever‐smokers: A retrospective nested case‐control study in two prospective cohorts
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| Názov: | Assessment of the EarlyCDT‐Lung test as an early biomarker of lung cancer in ever‐smokers: A retrospective nested case‐control study in two prospective cohorts |
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| Autori: | Wendy Yi‐Ying Wu, Zahra Haider, Xiaoshuang Feng, Alicia K. Heath, Anne Tjønneland, Antonio Agudo, Giovanna Masala, Hilary A. Robbins, José‐María Huerta, Marcela Guevara, Matthias B. Schulze, Miguel Rodriguez‐Barranco, Paolo Vineis, Rosario Tumino, Rudolf Kaaks, Renée T. Fortner, Sabina Sieri, Salvatore Panico, Therese Haugdahl Nøst, Torkjel M. Sandanger, Tonje Braaten, Mattias Johansson, Beatrice Melin, Mikael Johansson |
| Prispievatelia: | Health Research Fund (FIS) - Instituto de Salud Carlos III (ISCIII), World Cancer Research Fund (WCRF), International Agency for Research on Cancer (IARC), Regional Governments of Andalucía, Asturias, Basque Country, Murcia and Navarra, and the Catalan Institute of Oncology - ICO (Spain) |
| Zdroj: | RISalud-ANDALUCIA. Repositorio Institucional de Salud de Andalucía instname Wu, W Y-Y, Haider, Z, Feng, X, Heath, A K, Tjønneland, A, Agudo, A, Masala, G, Robbins, H A, Huerta, M-J, Guevara, M, Schulze, M B, Rodriguez-Barranco, M, Vineis, P, Tumino, R, Kaaks, R, Fortner, R T, Sieri, S, Panico, S, Nost, T H, Sandanger, T M, Braaten, T, Johansson, M, Melin, B & Johansson, M 2023, ' Assessment of the EarlyCDT-Lung test as an early biomarker of lung cancer in ever-smokers : A retrospective nested case-control study in two prospective cohorts ', International Journal of Cancer, vol. 159, no. 9, pp. 2002-2010 . https://doi.org/10.1002/ijc.34340 |
| Informácie o vydavateľovi: | Wiley, 2022. |
| Rok vydania: | 2022 |
| Predmety: | Lung Neoplasms, Neoplasias pulmonares, VALIDATION, Estudios retrospectivos, 03 medical and health sciences, 0302 clinical medicine, AUTOANTIBODY TEST, Estudios prospectivos, Humans, Prospective Studies, Lung, Early Detection of Cancer, Retrospective Studies, Cancer och onkologi, Smokers, Estudios de casos y controles, biomarkers, EarlyCDT-Lung test, Humanos, 3. Good health, lung cancer, Biomarcadores, Detección precoz del cáncer, prediagnostic samples, Pulmón, Cancer and Oncology, Case-Control Studies, Fumadores, Biomarkers |
| Popis: | The EarlyCDT‐Lung test is a blood‐based autoantibody assay intended to identify high‐risk individuals for low‐dose computed tomography lung cancer screening. However, there is a paucity of evidence on the performance of the EarlyCDT‐Lung test in ever‐smokers. We conducted a nested case‐control study within two prospective cohorts to evaluate the risk‐discriminatory performance of the EarlyCDT‐Lung test using prediagnostic blood samples from 154 future lung cancer cases and 154 matched controls. Cases were selected from those who had ever smoked and had a prediagnostic blood sample |
| Druh dokumentu: | Article |
| Popis súboru: | application/pdf |
| Jazyk: | English |
| ISSN: | 1097-0215 0020-7136 |
| DOI: | 10.1002/ijc.34340 |
| Prístupová URL adresa: | https://pubmed.ncbi.nlm.nih.gov/36305647 http://hdl.handle.net/10668/22117 https://hdl.handle.net/10037/28191 http://hdl.handle.net/10044/1/100406 https://curis.ku.dk/ws/files/338520477/Fulltext.pdf http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-201192 |
| Rights: | CC BY NC ND |
| Prístupové číslo: | edsair.doi.dedup.....ceb9568acf5d6254c9349d87b0fba834 |
| Databáza: | OpenAIRE |
| Abstrakt: | The EarlyCDT‐Lung test is a blood‐based autoantibody assay intended to identify high‐risk individuals for low‐dose computed tomography lung cancer screening. However, there is a paucity of evidence on the performance of the EarlyCDT‐Lung test in ever‐smokers. We conducted a nested case‐control study within two prospective cohorts to evaluate the risk‐discriminatory performance of the EarlyCDT‐Lung test using prediagnostic blood samples from 154 future lung cancer cases and 154 matched controls. Cases were selected from those who had ever smoked and had a prediagnostic blood sample |
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| ISSN: | 10970215 00207136 |
| DOI: | 10.1002/ijc.34340 |
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