Effects of kenyan black tea water soluble components on theaflavins interaction with antibiotics against selected pathogenic bacteria

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Názov: Effects of kenyan black tea water soluble components on theaflavins interaction with antibiotics against selected pathogenic bacteria
Autori: ANDREW BOR, EUCHARIA KENYA, JOHN J.N. MBITHI, CHARLES MUTAI
Zdroj: Asian Journal of Tropical Biotechnology. 14:47-59
Informácie o vydavateľovi: UNS Solo, 2017.
Rok vydania: 2017
Predmety: 2. Zero hunger, Tea --Composition, Antioxidants --Therapeutic use, Black tea --Health aspects, Tea --Chemistry, 6. Clean water, 3. Good health
Popis: Bor A, Kenya E, Mbithi JJN, Mutai C. 2017. Effects of Kenyan black tea water soluble components on theaflavins interaction with antibiotics against selected pathogenic bacteria. Bioteknologi 14: 47-59. This research is intended at differentiating the antibacterial activities of hot water extract of black tea having 18 µg/mL of theaflavins and 18 µg/mL of isolated theaflavins and their blend with antibiotics such as ampicillin. Their blended impacts with antibiotics were resolved by utilizing disk diffusion and modified Checkerboard method. The chi-square test was used to test the null hypothesis, which stated that water soluble components have no effect on theaflavins interaction with antibiotics. The water-soluble components of black tea extract were extracted with hot water, with the theaflavins being measured using the Flavognost method. Similar amounts of theaflavins were extracted using organic solvents and silica gel column chromatography. The concentrates of hot water extract and isolated theaflavins showed synergistic activity with selected antibiotics. However, the level of synergism differed significantly at P
Druh dokumentu: Article
Other literature type
Thesis
ISSN: 2775-4715
2775-300X
DOI: 10.13057/biotek/c140204
Prístupová URL adresa: https://smujo.id/bbs/article/download/2374/2163
https://ir-library.ku.ac.ke/bitstream/123456789/7240/1/Andrew%20Bor.pdf
https://ir-library.ku.ac.ke/handle/123456789/7240
https://smujo.id/bbs/article/view/2374
http://thesisbank.jhia.ac.ke/id/eprint/1747
Prístupové číslo: edsair.doi.dedup.....c261324a743b58fb3c64e4ed6a8bd487
Databáza: OpenAIRE
Popis
Abstrakt:Bor A, Kenya E, Mbithi JJN, Mutai C. 2017. Effects of Kenyan black tea water soluble components on theaflavins interaction with antibiotics against selected pathogenic bacteria. Bioteknologi 14: 47-59. This research is intended at differentiating the antibacterial activities of hot water extract of black tea having 18 µg/mL of theaflavins and 18 µg/mL of isolated theaflavins and their blend with antibiotics such as ampicillin. Their blended impacts with antibiotics were resolved by utilizing disk diffusion and modified Checkerboard method. The chi-square test was used to test the null hypothesis, which stated that water soluble components have no effect on theaflavins interaction with antibiotics. The water-soluble components of black tea extract were extracted with hot water, with the theaflavins being measured using the Flavognost method. Similar amounts of theaflavins were extracted using organic solvents and silica gel column chromatography. The concentrates of hot water extract and isolated theaflavins showed synergistic activity with selected antibiotics. However, the level of synergism differed significantly at P
ISSN:27754715
2775300X
DOI:10.13057/biotek/c140204