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Identifying predictors of a favourable outcome for outpatients with a persistent depressive disorder treated with Cognitive Behavioural Analysis System of Psychotherapy: A prospective cohort study: A prospective cohort study

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Title: Identifying predictors of a favourable outcome for outpatients with a persistent depressive disorder treated with Cognitive Behavioural Analysis System of Psychotherapy: A prospective cohort study: A prospective cohort study
Authors: Juliana A. Dean, Marieke J. Eldering, Robert A. Schoevers, Catheleine M. G. van Driel
Source: British Journal of Clinical Psychology. 63:244-257
Publisher Information: Wiley, 2024.
Publication Year: 2024
Subject Terms: Male, Adult, Depressive Disorder, Cognitive Behavioral Therapy, precision medicine, 05 social sciences, persistent depressive disorder, Middle Aged, Cognitive Behavioural Analysis System of Psychotherapy, Severity of Illness Index, 3. Good health, psychotherapy, Young Adult, 03 medical and health sciences, Treatment Outcome, 0302 clinical medicine, depressive disorder, Outpatients, Psychotherapy, Group, Humans, Female, 0501 psychology and cognitive sciences, dysthymic disorder, Prospective Studies, Aged
Description: ObjectivesCognitive Behavioural Analysis System of Psychotherapy (CBASP) is the first therapy specifically developed for persistent depressive disorder (PDD). This study aimed to identify predictors of favourable treatment outcome after group CBASP and assess change in depression severity over 24 weeks.DesignA prospective cohort study was conducted in patients with PDD treated with group‐CBASP.MethodsOutcomes were depression severity measured by the Inventory of Depression Severity—self‐report (IDS‐SR) after 6 and 12 months. Potential predictors investigated were baseline depression severity, prior antidepressant use, age, family status, income source, age of onset and childhood trauma. Multivariate logistic regression was performed to assess their effects with a ≥25% IDS‐SR score decrease as the dependent variable.ResultsThe IDS‐SR score (range 0–84) significantly decreased from 37.78 at start to 33.45 at 6 months, an improvement which was maintained at 12 months. Having paid work and no axis I comorbidity significantly predicted favourable response. In the groups without a favourable outcome predictor a substantial percentage still showed at least partial response (16.7% and 19.2%).ConclusionsSource of income and axis I comorbidity were predictors of response to group‐CBASP. Within the group without favourable outcome predictors, a subgroup showed at least partial response. These results suggest that group‐CBASP has promise for patients who do not respond to standard treatments. Future studies should include outcome measures that take into account comorbidity and other clinically relevant changes, such as social functioning.
Document Type: Article
Language: English
ISSN: 2044-8260
0144-6657
DOI: 10.1111/bjc.12454
Access URL: https://pubmed.ncbi.nlm.nih.gov/38312067
https://hdl.handle.net/11370/430e8e00-aa1e-448c-8022-1764f6503d96
https://doi.org/10.1111/bjc.12454
https://research.rug.nl/en/publications/430e8e00-aa1e-448c-8022-1764f6503d96
Rights: CC BY
Accession Number: edsair.doi.dedup.....c12abe3570a4ea51585ca9eb6cbb1270
Database: OpenAIRE
Description
Abstract:ObjectivesCognitive Behavioural Analysis System of Psychotherapy (CBASP) is the first therapy specifically developed for persistent depressive disorder (PDD). This study aimed to identify predictors of favourable treatment outcome after group CBASP and assess change in depression severity over 24 weeks.DesignA prospective cohort study was conducted in patients with PDD treated with group‐CBASP.MethodsOutcomes were depression severity measured by the Inventory of Depression Severity—self‐report (IDS‐SR) after 6 and 12 months. Potential predictors investigated were baseline depression severity, prior antidepressant use, age, family status, income source, age of onset and childhood trauma. Multivariate logistic regression was performed to assess their effects with a ≥25% IDS‐SR score decrease as the dependent variable.ResultsThe IDS‐SR score (range 0–84) significantly decreased from 37.78 at start to 33.45 at 6 months, an improvement which was maintained at 12 months. Having paid work and no axis I comorbidity significantly predicted favourable response. In the groups without a favourable outcome predictor a substantial percentage still showed at least partial response (16.7% and 19.2%).ConclusionsSource of income and axis I comorbidity were predictors of response to group‐CBASP. Within the group without favourable outcome predictors, a subgroup showed at least partial response. These results suggest that group‐CBASP has promise for patients who do not respond to standard treatments. Future studies should include outcome measures that take into account comorbidity and other clinically relevant changes, such as social functioning.
ISSN:20448260
01446657
DOI:10.1111/bjc.12454