D-Mannose as a Preservative of Glucose in Blood Samples
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| Názov: | D-Mannose as a Preservative of Glucose in Blood Samples |
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| Autori: | Chan, AYW, Ho, CS, Chan, TYK, Swaminathan, R |
| Zdroj: | Clinical Chemistry. 38:411-413 |
| Informácie o vydavateľovi: | Oxford University Press (OUP), 1992. |
| Rok vydania: | 1992 |
| Predmety: | Blood Glucose - Metabolism, 0301 basic medicine, Adult, Blood Glucose, Potassium - Blood, Sodium, 3. Good health, Kinetics, 03 medical and health sciences, Glycolysis - Drug Effects, Mannose - Pharmacology, Sodium Fluoride - Pharmacology, 0302 clinical medicine, Drug Stability, Sodium - Blood, Potassium, Humans, Sodium Fluoride, Glycolysis, Mannose |
| Popis: | We studied the changes in blood glucose concentration in blood samples collected in heparinized specimen tubes containing no other preservative, or containing NaF, D-mannose, or a combination of NaF and D-mannose. Blood concentration in samples taken into NaF decreased by 0.40 mmol/L in the first 2 h; thereafter, there was no change. In samples collected into mannose there was a small but significant decrease in blood glucose concentration with time. When samples containing mannose were analyzed immediately after collection, the concentration of glucose was higher than in later analyses, probably because of an exchange of intracellular glucose for extracellular mannose. When a combination of NaF and mannose was used, the blood glucose concentration was relatively stable but slightly higher than nonpreserved samples for the next 24 h. However, samples containing mannose were unsuitable for electrolyte analysis. We conclude that a combination of D-mannose and NaF may be a better preservative for blood glucose than either compound alone. |
| Druh dokumentu: | Article |
| Jazyk: | English |
| ISSN: | 1530-8561 0009-9147 |
| DOI: | 10.1093/clinchem/38.3.411 |
| Prístupová URL adresa: | https://pubmed.ncbi.nlm.nih.gov/1547561 https://www.ncbi.nlm.nih.gov/pubmed/1547561 http://clinchem.aaccjnls.org/content/38/3/411.short http://hub.hku.hk/handle/10722/168910 https://academic.oup.com/clinchem/article/38/3/411/5650196 http://hdl.handle.net/10722/168910 |
| Rights: | OUP Standard Publication Reuse |
| Prístupové číslo: | edsair.doi.dedup.....bec300c38a3512b5c5051ee28a79c14b |
| Databáza: | OpenAIRE |
Nájsť tento článok vo Web of Science | Abstrakt: | We studied the changes in blood glucose concentration in blood samples collected in heparinized specimen tubes containing no other preservative, or containing NaF, D-mannose, or a combination of NaF and D-mannose. Blood concentration in samples taken into NaF decreased by 0.40 mmol/L in the first 2 h; thereafter, there was no change. In samples collected into mannose there was a small but significant decrease in blood glucose concentration with time. When samples containing mannose were analyzed immediately after collection, the concentration of glucose was higher than in later analyses, probably because of an exchange of intracellular glucose for extracellular mannose. When a combination of NaF and mannose was used, the blood glucose concentration was relatively stable but slightly higher than nonpreserved samples for the next 24 h. However, samples containing mannose were unsuitable for electrolyte analysis. We conclude that a combination of D-mannose and NaF may be a better preservative for blood glucose than either compound alone. |
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| ISSN: | 15308561 00099147 |
| DOI: | 10.1093/clinchem/38.3.411 |