The Influence of Inflammation-Mediated Osteopenia (IMO) on the Structure of Rabbit Bone and Skin Collagen Fibrils
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| Titel: | The Influence of Inflammation-Mediated Osteopenia (IMO) on the Structure of Rabbit Bone and Skin Collagen Fibrils |
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| Autoren: | Kounadi, E., Fountos, G., Tzaphlidou, M. |
| Quelle: | Connective Tissue Research. 37:69-76 |
| Verlagsinformationen: | Informa UK Limited, 1998. |
| Publikationsjahr: | 1998 |
| Schlagwörter: | Collagen/*chemistry/metabolism/ultrastructure, Inflammation, 0301 basic medicine, 0303 health sciences, Tibia, Injections, Subcutaneous, Tibia/pathology/ultrastructure, Skin/metabolism/*pathology/ultrastructure, Bone and Bones, Bone Diseases, Metabolic, 03 medical and health sciences, Magnesium Silicates/administration & dosage, Magnesium Silicates, Inflammation/chemically induced/physiopathology, Bone and Bones/*pathology/ultrastructure, Animals, Female, Collagen, Rabbits, Bone Diseases, Metabolic/etiology/*pathology, Skin |
| Beschreibung: | The influence of Inflammation Mediated Osteopenia (IMO) on rabbit skin and bone (trabecular and cortical) collagen fibrils was studied by electron microscopy. Severe abnormalities in collagen fibril structure were detected, at the ultrastructural level, in skin and bone specimens from IMO rabbits. In treated animals the arrangement of fibrils is anarchic. The overall collagen fibril architecture is disturbed compared to normal. IMO collagen fibrils' mean diameter values were significantly larger than those from controls, in all examined tissues. However, the banding patterns of fibrils were normal in all cases. Computer analysis shows no differences in charged amino acid composition between IMO and untreated samples. Our results show a correlation between the effects induced by osteopenia on skin and bone collagen. |
| Publikationsart: | Article |
| Sprache: | English |
| ISSN: | 1607-8438 0300-8207 |
| DOI: | 10.3109/03008209809028901 |
| Zugangs-URL: | https://pubmed.ncbi.nlm.nih.gov/9643648 https://www.tandfonline.com/doi/abs/10.3109/03008209809028901 https://www.ncbi.nlm.nih.gov/pubmed/9643648 https://pubmed.ncbi.nlm.nih.gov/9643648/ http://olympias.lib.uoi.gr/jspui/handle/123456789/24287 |
| Dokumentencode: | edsair.doi.dedup.....bd0523a4cf20ac4b8c4acbae8fe2b0a7 |
| Datenbank: | OpenAIRE |
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Nájsť tento článok vo Web of Science | Abstract: | The influence of Inflammation Mediated Osteopenia (IMO) on rabbit skin and bone (trabecular and cortical) collagen fibrils was studied by electron microscopy. Severe abnormalities in collagen fibril structure were detected, at the ultrastructural level, in skin and bone specimens from IMO rabbits. In treated animals the arrangement of fibrils is anarchic. The overall collagen fibril architecture is disturbed compared to normal. IMO collagen fibrils' mean diameter values were significantly larger than those from controls, in all examined tissues. However, the banding patterns of fibrils were normal in all cases. Computer analysis shows no differences in charged amino acid composition between IMO and untreated samples. Our results show a correlation between the effects induced by osteopenia on skin and bone collagen. |
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| ISSN: | 16078438 03008207 |
| DOI: | 10.3109/03008209809028901 |