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A three-year review of lung cancer patient characteristics in a tertiary hospital

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Název: A three-year review of lung cancer patient characteristics in a tertiary hospital
Autoři: Afriyie-Mensah, Jane S, Kwarteng, Ernest, Tetteh, John, Gbadamosi, Hafi, Dadzie, Mary-Ann, Mensah, Yaw Boakye, Entsua-Mensah, Ekow
Zdroj: Ghana Med J
Ghana Medical Journal; Vol. 57 No. 3 (2023): September 2023; 167-174
Afriyie-Mensah, J S, Kwarteng, E, Tetteh, J, Gbadamosi, H, Dadzie, M-A, Mensah, Y B & Entsua-Mensah, E 2023, ' A three-year review of lung cancer patient characteristics in a tertiary hospital ', Ghana medical journal, vol. 57, no. 3, pp. 167-174 . https://doi.org/10.4314/gmj.v57i3.2
Informace o vydavateli: African Journals Online (AJOL), 2023.
Rok vydání: 2023
Témata: Male, Adult, Chest Pain, Lung Neoplasms, Anaplastic Lymphoma Kinase (ALK), ErbB Receptors/genetics, Adenocarcinoma/epidemiology, Lung Neoplasms/epidemiology, Adenocarcinoma, Ghana, Tertiary Care Centers, Cough/etiology, 80 and over, Humans, Ghana/epidemiology, Retrospective Studies, Aged, Neoplasm Staging, Aged, 80 and over, Chest Pain/etiology, Smoking, Smoking/epidemiology, Middle Aged, Epidermal growth factor receptor (EGFR), Lung Cancer, ErbB Receptors, Cough, Original Article, Female
Popis: Objective: The study sought to determine clinical characteristics and histologic subtypes of a cohort of lung cancer patients in a tertiary facility.Design: Retrospective review of the medical records of histology-confirmed lung cancer cases at the respiratory clinic over a 3-year period.Setting: Respiratory Clinic, Korle-Bu Teaching Hospital, Accra, GhanaParticipants: All adult patients with histologically diagnosed lung cancer were enrolled.Main outcome measures: Lung cancer histological typesResults: The proportion of lung cancer cases was 12.4%. The majority were women (57.8%) and the mean age at diagnosis was 55.8±16.0 years. The patients were predominantly non-smokers (61%). Common symptoms were chronic cough and chest pain. More than two-thirds of the cases presented in clinical stages III and IV with the pre-dominant histological subtype being adenocarcinoma in smokers and non-smokers. Genetic testing for epidermal growth factor receptor (EGFR) and Anaplastic Lymphoma kinase (ALK) mutations were largely absent.Conclusions: The majority of lung cancer patients presented late with advanced disease. Adenocarcinoma was the predominant histological subtype in a predominantly non-smoking population, with an increased prevalence among women less than 60 years. This should encourage testing for genetic mutations to improve patient survival.
Druh dokumentu: Article
Other literature type
Popis souboru: application/pdf
ISSN: 0016-9560
DOI: 10.4314/gmj.v57i3.2
Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38957673
https://www.ajol.info/index.php/gmj/article/view/255157
Rights: URL: http://creativecommons.org/licenses/by/4.0/This is an Open Access article under the CC (http://creativecommons.org/licenses/by/4.0/) BY license.
Přístupové číslo: edsair.doi.dedup.....bc1eb944ea3211410d115445b69b1b36
Databáze: OpenAIRE
Popis
Abstrakt:Objective: The study sought to determine clinical characteristics and histologic subtypes of a cohort of lung cancer patients in a tertiary facility.Design: Retrospective review of the medical records of histology-confirmed lung cancer cases at the respiratory clinic over a 3-year period.Setting: Respiratory Clinic, Korle-Bu Teaching Hospital, Accra, GhanaParticipants: All adult patients with histologically diagnosed lung cancer were enrolled.Main outcome measures: Lung cancer histological typesResults: The proportion of lung cancer cases was 12.4%. The majority were women (57.8%) and the mean age at diagnosis was 55.8±16.0 years. The patients were predominantly non-smokers (61%). Common symptoms were chronic cough and chest pain. More than two-thirds of the cases presented in clinical stages III and IV with the pre-dominant histological subtype being adenocarcinoma in smokers and non-smokers. Genetic testing for epidermal growth factor receptor (EGFR) and Anaplastic Lymphoma kinase (ALK) mutations were largely absent.Conclusions: The majority of lung cancer patients presented late with advanced disease. Adenocarcinoma was the predominant histological subtype in a predominantly non-smoking population, with an increased prevalence among women less than 60 years. This should encourage testing for genetic mutations to improve patient survival.
ISSN:00169560
DOI:10.4314/gmj.v57i3.2