Peripheral and central pathogenesis of postherpetic neuralgia
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| Název: | Peripheral and central pathogenesis of postherpetic neuralgia |
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| Autoři: | Liu, Qiuping, Han, Jingxian, Zhang, Xuezhu |
| Zdroj: | Skin Res Technol |
| Informace o vydavateli: | Wiley, 2024. |
| Rok vydání: | 2024 |
| Témata: | 0301 basic medicine, Central Nervous System Sensitization, 03 medical and health sciences, 0302 clinical medicine, Peripheral Nerve Injuries, Neuralgia, Postherpetic, Humans, Brain, Original Article |
| Popis: | BackgroundPostherpetic neuralgia (PHN) is a classic chronic condition with multiple signs of peripheral and central neuropathy. Unfortunately, the pathogenesis of PHN is not well defined, limiting clinical treatment and disease management.ObjectiveTo describe the peripheral and central pathological axes of PHN, including peripheral nerve injury, inflammation induction, central nervous system sensitization, and brain functional and structural network activity.MethodsA bibliographic survey was carried out, selecting relevant articles that evaluated the characterization of the pathogenesis of PHN, including peripheral and central pathological axes.ResultsCurrently, due to the complexity of the pathophysiological mechanisms of PHN and the incomplete understanding of the exact mechanism of neuralgia.ConclusionIt is essential to conduct in‐depth research to clarify the origins of PHN pathogenesis and explore effective and comprehensive therapies for PHN. |
| Druh dokumentu: | Article Other literature type |
| Jazyk: | English |
| ISSN: | 1600-0846 0909-752X |
| DOI: | 10.1111/srt.13867 |
| Přístupová URL adresa: | https://pubmed.ncbi.nlm.nih.gov/39101621 |
| Rights: | CC BY NC ND URL: http://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
| Přístupové číslo: | edsair.doi.dedup.....bac51465ffe4e1c68389693ee06b3513 |
| Databáze: | OpenAIRE |
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Nájsť tento článok vo Web of Science | Abstrakt: | BackgroundPostherpetic neuralgia (PHN) is a classic chronic condition with multiple signs of peripheral and central neuropathy. Unfortunately, the pathogenesis of PHN is not well defined, limiting clinical treatment and disease management.ObjectiveTo describe the peripheral and central pathological axes of PHN, including peripheral nerve injury, inflammation induction, central nervous system sensitization, and brain functional and structural network activity.MethodsA bibliographic survey was carried out, selecting relevant articles that evaluated the characterization of the pathogenesis of PHN, including peripheral and central pathological axes.ResultsCurrently, due to the complexity of the pathophysiological mechanisms of PHN and the incomplete understanding of the exact mechanism of neuralgia.ConclusionIt is essential to conduct in‐depth research to clarify the origins of PHN pathogenesis and explore effective and comprehensive therapies for PHN. |
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| ISSN: | 16000846 0909752X |
| DOI: | 10.1111/srt.13867 |