First episode depression during the perinatal period is associated with atopic diseases and persistently increased eosinophil and basophil levels
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| Názov: | First episode depression during the perinatal period is associated with atopic diseases and persistently increased eosinophil and basophil levels |
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| Autori: | Wagner, E.N., Pichler, E.M., Müller, M., Eisenhut, A., Buadze, A., Xu, Y., Seifritz, E., Strippoli, M.F., Castelao, E., Ranjbar, S., Glaus, J., Vandeleur, C., Preisig, M., von Känel, R., Ajdacic-Gross, V. |
| Zdroj: | Arch Womens Ment Health Archives of women's mental health, vol. 28, no. 3, pp. 639-644 |
| Informácie o vydavateľovi: | Springer Science and Business Media LLC, 2024. |
| Rok vydania: | 2024 |
| Predmety: | Short Communication, Humans, Female, Pregnancy, Basophils/immunology, Eosinophils/immunology, Adult, Pregnancy Complications/psychology, Pregnancy Complications/epidemiology, Hypersensitivity/epidemiology, Hypersensitivity/psychology, Depression/epidemiology, Asthma/epidemiology, Young Adult, Atopy, Basophils, Depression, Eosinophils, Perinatal |
| Popis: | Purpose A previous diagnosis of depression is a strong predictor for perinatal depression, apart from other mental disorders, stress, and atopies. It is less clear which factors interfere if perinatal depression occurs as a first depression episode (fePND). Methods We examined the associations with atopies and related blood parameters using data of CoLaus|PsyCoLaus. Results Newly occurring depression during the perinatal period but not recurrent depression was associated with a lifetime diagnosis of allergies and asthma together with persistently increased levels of basophils and eosinophils. Conclusion The results imply that immune function may play a relevant role in the risk of a fePND. If confirmed and detailed, these findings could serve as the basis for designing preliminary prevention strategies by observing eosinophil and basophil levels as well as symptoms of atopic diseases before/during pregnancy. |
| Druh dokumentu: | Article Other literature type |
| Popis súboru: | application/pdf |
| Jazyk: | English |
| ISSN: | 1435-1102 1434-1816 |
| DOI: | 10.1007/s00737-024-01522-5 |
| Prístupová URL adresa: | https://pubmed.ncbi.nlm.nih.gov/39412540 https://serval.unil.ch/notice/serval:BIB_BF8C45D12DE0 https://serval.unil.ch/resource/serval:BIB_BF8C45D12DE0.P001/REF.pdf http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_BF8C45D12DE08 |
| Rights: | CC BY |
| Prístupové číslo: | edsair.doi.dedup.....ba471f2beb25950cbecc4a75b4b821e1 |
| Databáza: | OpenAIRE |
| Abstrakt: | Purpose A previous diagnosis of depression is a strong predictor for perinatal depression, apart from other mental disorders, stress, and atopies. It is less clear which factors interfere if perinatal depression occurs as a first depression episode (fePND). Methods We examined the associations with atopies and related blood parameters using data of CoLaus|PsyCoLaus. Results Newly occurring depression during the perinatal period but not recurrent depression was associated with a lifetime diagnosis of allergies and asthma together with persistently increased levels of basophils and eosinophils. Conclusion The results imply that immune function may play a relevant role in the risk of a fePND. If confirmed and detailed, these findings could serve as the basis for designing preliminary prevention strategies by observing eosinophil and basophil levels as well as symptoms of atopic diseases before/during pregnancy. |
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| ISSN: | 14351102 14341816 |
| DOI: | 10.1007/s00737-024-01522-5 |
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