Diversity of cultivable fungi associated with Antarctic marine sponges and screening for their antimicrobial, antitumoral and antioxidant potential
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| Název: | Diversity of cultivable fungi associated with Antarctic marine sponges and screening for their antimicrobial, antitumoral and antioxidant potential |
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| Autoři: | Henríquez, Marlene, Vergara, Karen, Norambuena, Javiera, Beiza, Andrea, Maza, Felipe, Ubilla, Pamela, Araya, Ivanna, Chávez, Renato, San-Martín, Aurelio, Darias, José, Darias, María, Vaca, Inmaculada |
| Přispěvatelé: | Fondo Nacional de Desarrollo Científico y Tecnológico (Chile), Instituto Antártico Chileno, Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72], Herrada, Anthony, Universidad de Chile = University of Chile Santiago (UCHILE), Universidad de Santiago de Chile Santiago (USACH), Instituto de Productos Naturales y Agrobiologia = Institute of Natural Products and Agrobiology (IPNA), Institut des Sciences de l'Evolution de Montpellier (UMR ISEM), Centre de Coopération Internationale en Recherche Agronomique pour le Développement (Cirad)-École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Université de Montpellier (UM)-Institut de recherche pour le développement IRD : UR226-Centre National de la Recherche Scientifique (CNRS) |
| Zdroj: | Digital.CSIC. Repositorio Institucional del CSIC instname Consejo Superior de Investigaciones Científicas (CSIC) Conicyt_qa ANID instacron:ANID Articulos_ANID Agencia Nacional de Investigación y Desarrollo WORLD JOURNAL OF MICROBIOLOGY & BIOTECHNOLOGY Artículos CONICYT CONICYT Chile instacron:CONICYT |
| Informace o vydavateli: | Springer Science and Business Media LLC, 2013. |
| Rok vydání: | 2013 |
| Témata: | 0301 basic medicine, ACTION ANTITUMORALE, Antarctic Sponges, MESH: Porifera, ANTIOXYDANT, Antarctic Regions, Antineoplastic Agents, MESH: Ascomycota, PHENOTYPE, Antitumoral, Antioxidants, CHAMPIGNON, MESH: Sequence Analysis, 03 medical and health sciences, Ascomycota, MESH: Anti-Bacterial Agents, MESH: Antarctic Regions, DNA, Ribosomal Spacer, Animals, PHYLOGENIE, MESH: Animals, SYMBIOSE, 14. Life underwater, Geomyces sp. Antimicrobial, ACTIVITE ANTIBACTERIENNE, [SDV.MP] Life Sciences [q-bio]/Microbiology and Parasitology, ALGUE MARINE, 0303 health sciences, ACTIVITE BIOLOGIQUE, Antarctic sponges, MESH: Antioxidants, MICROORGANISME, MESH: DNA, Fungi, DNA, Sequence Analysis, DNA, 15. Life on land, Anti-Bacterial Agents, Porifera, Ribosomal Spacer, [SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology, 13. Climate action, MESH: Antineoplastic Agents, Antioxidant |
| Popis: | The diversity of sponge-associated fungi has been poorly investigated in remote geographical areas like Antarctica. In this study, 101 phenotypically different fungal isolates were obtained from 11 sponge samples collected in King George Island, Antarctica. The analysis of ITS sequences revealed that they belong to the phylum Ascomycota. Sixty-five isolates belong to the genera Geomyces, Penicillium, Epicoccum, Pseudeurotium, Thelebolus, Cladosporium, Aspergillus, Aureobasidium, Phoma, and Trichocladium but 36 isolates could not be identified at genus level. In order to estimate the potential of these isolates as producers of interesting bioactivities, antimicrobial, antitumoral and antioxidant activities of fungal culture extracts were assayed. Around 51% of the extracts, mainly from the genus Geomyces and non identified relatives, showed antimicrobial activity against some of the bacteria tested. On the other hand, around 42% of the extracts showed potent antitumoral activity, Geomyces sp. having the best performance. Finally, the potential of the isolated fungi as producers of antioxidant activity seems to be moderate. Our results suggest that fungi associated with Antarctic sponges, particularly Geomyces, would be valuable sources of antimicrobial and antitumoral compounds. To our knowledge, this is the first report describing the biodiversity and the metabolic potential of fungi associated with Antarctic marine sponges. |
| Druh dokumentu: | Article |
| Popis souboru: | application/pdf |
| Jazyk: | English |
| ISSN: | 1573-0972 0959-3993 |
| DOI: | 10.1007/s11274-013-1418-x |
| DOI: | 10.13039/501100002850 |
| Přístupová URL adresa: | https://pubmed.ncbi.nlm.nih.gov/23824664 http://hdl.handle.net/10261/180418 https://hal.umontpellier.fr/hal-03019849v1 https://doi.org/10.1007/s11274-013-1418-x http://repositorio.uchile.cl/bitstream/2250/119855/1/Diversity-of-cultivable-fungi-associated-with-Antarctic-marine-sponges-and-screening-for-their-antimicrobial-antitumoral-and-antioxidant-potential.pdf http://repositorio.uchile.cl/handle/2250/119855 https://link.springer.com/article/10.1007/s11274-013-1418-x https://digital.csic.es/handle/10261/180418 http://repositorio.conicyt.cl/handle/10533/128352 https://europepmc.org/article/AGR/IND500715631 https://repositorio-qa.anid.cl/handle/10533/128352 https://hdl.handle.net/10533/128352 http://hdl.handle.net/10533/128352 |
| Rights: | Springer TDM CC BY NC ND |
| Přístupové číslo: | edsair.doi.dedup.....b8dcc04722c47eb0b3b9e132a8c1125a |
| Databáze: | OpenAIRE |
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Nájsť tento článok vo Web of Science | Abstrakt: | The diversity of sponge-associated fungi has been poorly investigated in remote geographical areas like Antarctica. In this study, 101 phenotypically different fungal isolates were obtained from 11 sponge samples collected in King George Island, Antarctica. The analysis of ITS sequences revealed that they belong to the phylum Ascomycota. Sixty-five isolates belong to the genera Geomyces, Penicillium, Epicoccum, Pseudeurotium, Thelebolus, Cladosporium, Aspergillus, Aureobasidium, Phoma, and Trichocladium but 36 isolates could not be identified at genus level. In order to estimate the potential of these isolates as producers of interesting bioactivities, antimicrobial, antitumoral and antioxidant activities of fungal culture extracts were assayed. Around 51% of the extracts, mainly from the genus Geomyces and non identified relatives, showed antimicrobial activity against some of the bacteria tested. On the other hand, around 42% of the extracts showed potent antitumoral activity, Geomyces sp. having the best performance. Finally, the potential of the isolated fungi as producers of antioxidant activity seems to be moderate. Our results suggest that fungi associated with Antarctic sponges, particularly Geomyces, would be valuable sources of antimicrobial and antitumoral compounds. To our knowledge, this is the first report describing the biodiversity and the metabolic potential of fungi associated with Antarctic marine sponges. |
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| ISSN: | 15730972 09593993 |
| DOI: | 10.1007/s11274-013-1418-x |