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Predictive Validity of Psychometrically Assessed Schizotypy for Psychopathology Dimensions and Functioning in an 8-Year Multiwave Study

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Title: Predictive Validity of Psychometrically Assessed Schizotypy for Psychopathology Dimensions and Functioning in an 8-Year Multiwave Study
Authors: Neus Barrantes-Vidal, Thomas R Kwapil
Source: Schizophr Bull
Dipòsit Digital de Documents de la UAB
Universitat Autònoma de Barcelona
Publisher Information: Oxford University Press (OUP), 2025.
Publication Year: 2025
Subject Terms: Developmental trajectories, Male, Adult, Psychiatric Status Rating Scales, Psychometrics, Adolescent, High-risk, Schizotypal Personality Disorder/diagnosis, Reproducibility of Results, Supplement Articles, Psychosisproneness, Psychosis, Schizotypal Personality Disorder, Young Adult, Psychosocial Functioning, Schizophrenia, Humans, Female, Negative symptoms, Longitudinal Studies, Psychiatric Status Rating Scales/standards, Psychometrics/standards
Description: Background and Hypothesis Although the psychometric high-risk method based on schizotypy has proven to be a highly cost-effective strategy for unraveling etiological factors for schizophrenia-spectrum disorders, there is a paucity of longitudinal studies with nonclinical populations. This study analyzed the predictive validity of positive and negative schizotypy in a longitudinal project (Barcelona Longitudinal Investigation of Schizotypy; BLISS) spanning a total of 7.8 years. Study Design At Time 1 (T1), 547 college students completed the Wisconsin Schizotypy Scales. We re-assessed subsamples (oversampled for high schizotypy to ensure variability) at 4 re-assessments. This study reports psychopathology, psychological, and functional outcomes assessed with self-report and interview (CAARMS, Negative Symptom Manual, SCID-II Cluster A) measures at T4 (n = 89; 4.4 years after T1) and self-report measures at T5 (n = 169; 7.8 years after T1). T1 positive and negative schizotypy were entered simultaneously as predictors in linear regression models. Study Results Positive schizotypy predicted positive symptoms at T4, whereas negative schizotypy predicted interview-rated negative symptoms and schizoid personality traits (even when controlling for mood and avoidant personality), and impaired social and global functioning. Both dimensions predicted suspiciousness, and schizotypal and paranoid personality traits, as well as low self-esteem and depression. Similarly, both dimensions predicted suspiciousness, depression, and poor social support at T5, whereas only positive schizotypy predicted low self-esteem, anxiety, and perceived stress. Conclusions Both schizotypy dimensions consistently showed a meaningful pattern of hypothesized differential and overlapping predictions, which supports their validity as distinct dimensions and their predictive validity in nonclinical samples.
Document Type: Article
Other literature type
File Description: application/pdf
Language: English
ISSN: 1745-1701
0586-7614
DOI: 10.1093/schbul/sbae140
Access URL: https://pubmed.ncbi.nlm.nih.gov/40037818
https://ddd.uab.cat/record/318330
Rights: CC BY
URL: http://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
Accession Number: edsair.doi.dedup.....b6d0632acd444390f52ec0b2db66787e
Database: OpenAIRE
Description
Abstract:Background and Hypothesis Although the psychometric high-risk method based on schizotypy has proven to be a highly cost-effective strategy for unraveling etiological factors for schizophrenia-spectrum disorders, there is a paucity of longitudinal studies with nonclinical populations. This study analyzed the predictive validity of positive and negative schizotypy in a longitudinal project (Barcelona Longitudinal Investigation of Schizotypy; BLISS) spanning a total of 7.8 years. Study Design At Time 1 (T1), 547 college students completed the Wisconsin Schizotypy Scales. We re-assessed subsamples (oversampled for high schizotypy to ensure variability) at 4 re-assessments. This study reports psychopathology, psychological, and functional outcomes assessed with self-report and interview (CAARMS, Negative Symptom Manual, SCID-II Cluster A) measures at T4 (n = 89; 4.4 years after T1) and self-report measures at T5 (n = 169; 7.8 years after T1). T1 positive and negative schizotypy were entered simultaneously as predictors in linear regression models. Study Results Positive schizotypy predicted positive symptoms at T4, whereas negative schizotypy predicted interview-rated negative symptoms and schizoid personality traits (even when controlling for mood and avoidant personality), and impaired social and global functioning. Both dimensions predicted suspiciousness, and schizotypal and paranoid personality traits, as well as low self-esteem and depression. Similarly, both dimensions predicted suspiciousness, depression, and poor social support at T5, whereas only positive schizotypy predicted low self-esteem, anxiety, and perceived stress. Conclusions Both schizotypy dimensions consistently showed a meaningful pattern of hypothesized differential and overlapping predictions, which supports their validity as distinct dimensions and their predictive validity in nonclinical samples.
ISSN:17451701
05867614
DOI:10.1093/schbul/sbae140