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Negative serology of Fasciola hepatica infection in patients with liver cancer in Peru: a preliminary report

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Název:	Negative serology of Fasciola hepatica infection in patients with liver cancer in Peru: a preliminary report
Autoři:	Claudia Machicado, Stéphane Bertani, Luis A. Marcos, Patricia Herrera-Velit, Eloy Ruiz, Jose R. Espinoza
Přispěvatelé:	Bertani, Stéphane
Zdroj:	Zaguán. Repositorio Digital de la Universidad de Zaragoza Universidad de Zaragoza instname Revista da Sociedade Brasileira de Medicina Tropical, Vol 51, Iss 2, Pp 231-233 Revista da Sociedade Brasileira de Medicina Tropical, Volume: 51, Issue: 2, Pages: 231-233, Published: APR 2018
Informace o vydavateli:	FapUNIFESP (SciELO), 2018.
Rok vydání:	2018
Témata:	Adult, Male, 0301 basic medicine, Fascioliasis, Carcinoma, Hepatocellular, Fascioliasis / diagnosis, Fasciolosis, Hepatocellular carcinoma, Immunoglobulin G / blood, RC955-962, Antibodies, Helminth, Liver Neoplasms / blood, Enzyme-Linked Immunosorbent Assay, Carcinoma Hepatocellular / blood, Antibodies, Fasciola hepatica / immunology, Cholangiocarcinoma, Young Adult, 03 medical and health sciences, 0302 clinical medicine, [SDV.CAN] Life Sciences [q-bio]/Cancer, Risk Factors, Hepatocellular / parasitology, Arctic medicine. Tropical medicine, Peru, Liver Neoplasms / parasitology, Animals, Humans, Aged, Fascioliasis / complications, Aged, 80 and over, [SDV.MHEP] Life Sciences [q-bio]/Human health and pathology, Carcinoma, Liver Neoplasms, Liver fluke, Fasciola hepatica, Middle Aged, Fibrosis, 3. Good health, Helminth / blood, Aged 80 and over, Immunoglobulin G, [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Female
Popis:	The etiology of several hepatocellular carcinoma (HCC) cases remains largely unknown. Although Fasciola hepatica has been associated with liver fibrosis in Latin America, it has not yet been associated with HCC. This study aimed to determine the existence of specific IgG antibodies against F. hepatica in the serum samples of HCC patients.In total, 13 serum samples from 13 HCC patients were screened using Fas2-ELISA.Fas2-ELISA demonstrated negative results in all HCC patients included in this study.The pre-existence of F. hepatica infection in HCC patients needs to be further investigated in epidemiological and experimental studies.
Druh dokumentu:	Article Other literature type
Popis souboru:	application/pdf; text/html; text/pdf
ISSN:	1678-9849 0037-8682
DOI:	10.1590/0037-8682-0180-2017
Přístupová URL adresa:	http://www.scielo.br/pdf/rsbmt/v51n2/1678-9849-rsbmt-51-02-231.pdf https://pubmed.ncbi.nlm.nih.gov/29768560 http://zaguan.unizar.es/record/70954 https://doaj.org/article/28074fae6b3d453e8d620c7226833086 http://www.scielo.br/pdf/rsbmt/v51n2/1678-9849-rsbmt-51-02-231.pdf http://www.scielo.br/j/rsbmt/a/yb9ScjHTnTKrxSBjcq8dvFD/ https://www.scielo.br/j/rsbmt/a/yb9ScjHTnTKrxSBjcq8dvFD/ https://core.ac.uk/display/160412593 https://www.ncbi.nlm.nih.gov/pubmed/29768560 https://www.cabdirect.org/cabdirect/abstract/20193029703 https://hal.science/hal-01793677v1/document https://doi.org/10.1590/0037-8682-0180-2017 https://hal.science/hal-01793677v1 https://hdl.handle.net/20.500.12866/4133 https://doi.org/10.1590/0037-8682-0180-2017 http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000200231&lng=en&tlng=en http://www.documentation.ird.fr/hor/fdi:010073026
Rights:	CC BY
Přístupové číslo:	edsair.doi.dedup.....aede448d1ddac2173657767c2409c0e3
Databáze:	OpenAIRE

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Abstrakt:	The etiology of several hepatocellular carcinoma (HCC) cases remains largely unknown. Although Fasciola hepatica has been associated with liver fibrosis in Latin America, it has not yet been associated with HCC. This study aimed to determine the existence of specific IgG antibodies against F. hepatica in the serum samples of HCC patients.In total, 13 serum samples from 13 HCC patients were screened using Fas2-ELISA.Fas2-ELISA demonstrated negative results in all HCC patients included in this study.The pre-existence of F. hepatica infection in HCC patients needs to be further investigated in epidemiological and experimental studies.
ISSN:	16789849 00378682
DOI:	10.1590/0037-8682-0180-2017