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Changes in health-related quality of life, depression, and fear of progression during oncological inpatient rehabilitation and beyond: a longitudinal study

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Názov: Changes in health-related quality of life, depression, and fear of progression during oncological inpatient rehabilitation and beyond: a longitudinal study
Autori: Giesler, Jürgen M., Weis, Joachim
Zdroj: Support Care Cancer
Informácie o vydavateľovi: Springer Science and Business Media LLC, 2024.
Rok vydania: 2024
Predmety: Male, Adult, Aged, 80 and over, Inpatients, Depression, Research, Prostatic Neoplasms, Surveys and Questionnaires [MeSH], Disease Progression [MeSH], Aged, 80 and over [MeSH], Cancer, Aged [MeSH], Breast Neoplasms/psychology [MeSH], Breast Neoplasms/rehabilitation [MeSH], Inpatients/statistics, Male [MeSH], Quality of Life [MeSH], Neoplasms/psychology [MeSH], Oncological rehabilitation, Prostatic Neoplasms/psychology [MeSH], Inpatients/psychology [MeSH], Depression/etiology [MeSH], Fear of progression, Female [MeSH], Follow-Up Studies [MeSH], Health-related quality of life, Adult [MeSH], Humans [MeSH], Survivorship, Longitudinal Studies [MeSH], Fear/psychology [MeSH], Middle Aged [MeSH], Prostatic Neoplasms/rehabilitation [MeSH], Colorectal Neoplasms/rehabilitation [MeSH], Neoplasms/rehabilitation [MeSH], Colorectal Neoplasms/psychology [MeSH], Breast Neoplasms, Fear, Middle Aged, Neoplasms, Surveys and Questionnaires, Quality of Life, Disease Progression, Humans, Female, Longitudinal Studies, Colorectal Neoplasms, Aged, Follow-Up Studies
Popis: Purpose Studies evaluating oncological inpatient rehabilitation rarely include follow-up intervals beyond 6 months and larger proportions of patients other than those with breast cancer. Therefore, this study investigated changes in health-related quality of life (HRQoL), depression, and fear of progression of patients with breast, colorectal, or prostate cancer from the beginning to the end of oncological rehabilitation and a 9-month follow-up. Methods Three hundred seventy-seven patients with breast, colorectal, or prostate cancer undergoing oncological inpatient rehabilitation (median age 61 years, 49% female) completed the EORTC QLQ-C30, the PHQ-9, and the FoP-Q-SF at each measurement point. Data analysis used 3 (tumor site) × 3 (time of measurement) repeated measures ANCOVAs with patient age and time since diagnosis as covariates. At each time point, we also compared our sample to the general population on the measures used. Results Having controlled for the covariates, we found significant effects of tumor site, which were small except for Diarrhea. Effects of time of measurement were often significant and in part at least medium in size indicating improvement of HRQoL and depression during rehabilitation. At follow-up, some HRQoL domains and depression deteriorated. Women with breast cancer, in particular, showed a greater decrease in emotional functioning then. Compared to the general population, the sample’s HRQoL and depression were significantly worse on most occasions. Conclusion Oncological inpatient rehabilitation may improve HRQoL. The subsequent and in part differential deterioration in some HRQoL domains suggests a need for further follow-up care within survivorship programs.
Druh dokumentu: Article
Other literature type
Popis súboru: pdf
Jazyk: English
ISSN: 1433-7339
0941-4355
DOI: 10.1007/s00520-024-08800-z
Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39225728
https://repository.publisso.de/resource/frl:6500133
Rights: CC BY
Prístupové číslo: edsair.doi.dedup.....a61d6cf3f23530a0af597611615b581a
Databáza: OpenAIRE
Popis
Abstrakt:Purpose Studies evaluating oncological inpatient rehabilitation rarely include follow-up intervals beyond 6 months and larger proportions of patients other than those with breast cancer. Therefore, this study investigated changes in health-related quality of life (HRQoL), depression, and fear of progression of patients with breast, colorectal, or prostate cancer from the beginning to the end of oncological rehabilitation and a 9-month follow-up. Methods Three hundred seventy-seven patients with breast, colorectal, or prostate cancer undergoing oncological inpatient rehabilitation (median age 61 years, 49% female) completed the EORTC QLQ-C30, the PHQ-9, and the FoP-Q-SF at each measurement point. Data analysis used 3 (tumor site) × 3 (time of measurement) repeated measures ANCOVAs with patient age and time since diagnosis as covariates. At each time point, we also compared our sample to the general population on the measures used. Results Having controlled for the covariates, we found significant effects of tumor site, which were small except for Diarrhea. Effects of time of measurement were often significant and in part at least medium in size indicating improvement of HRQoL and depression during rehabilitation. At follow-up, some HRQoL domains and depression deteriorated. Women with breast cancer, in particular, showed a greater decrease in emotional functioning then. Compared to the general population, the sample’s HRQoL and depression were significantly worse on most occasions. Conclusion Oncological inpatient rehabilitation may improve HRQoL. The subsequent and in part differential deterioration in some HRQoL domains suggests a need for further follow-up care within survivorship programs.
ISSN:14337339
09414355
DOI:10.1007/s00520-024-08800-z