Phylogeography and epidemiological history of West Nile virus genotype 1a in Europe and the Mediterranean basin
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| Title: | Phylogeography and epidemiological history of West Nile virus genotype 1a in Europe and the Mediterranean basin |
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| Authors: | G. Zehender, E. Ebranati, F. Bernini, A. Lo Presti, G. Rezza, M. Delogu, M. Galli, M. Ciccozzi |
| Source: | Infection, Genetics and Evolution. 11:646-653 |
| Publisher Information: | Elsevier BV, 2011. |
| Publication Year: | 2011 |
| Subject Terms: | 0301 basic medicine, Likelihood Functions, 0303 health sciences, Genotype, Mediterranean Region, WEST NILE VIRUS GENOTYPE 1A, SPATIO TEMPORAL PHYLODYNAMICS, BAYESIAN PHYLOGEOGRAPHY, WNV 2008/2009 ITALIAN EPIDEMIC, MIGRATORY BIRDS, Bayes Theorem, History, 20th Century, 3. Good health, Europe, Phylogeography, 03 medical and health sciences, West Nile virus genotype 1a, spatio temporal phylodynamics, Bayesian phylogeography, WNV 2008/2009 Italian epidemic, migratory birds, Mediterranean WNV, Humans, West Nile virus, Phylogeny, West Nile Fever |
| Description: | Aim of this study was to reconstruct the temporal and spatial phylodynamics of WNV-1a, the genotype to which the majority of European/Mediterranean viral strains belongs, by using sequences retrieved from public databases. WNV-1a isolates segregated into two major clades: the recent West Mediterranean sequences formed a single monophyletic group within clade A. Clade B included sequences from East Mediterranean and America. Phylogeographic analysis suggested that WNV-1a probably originated in sub-Saharan Africa in the early XXth century, and then spread northwards since the late 1970s, via two routes: one crossing Eastern Mediterranean and the other the Western Mediterranean countries. Our data suggest that the circulation of the virus in a given geographical area usually precedes the onset of the outbreak by one year or more, and underline the importance of the spatial-temporal phylodynamics reconstruction in clarifying the recent epidemiology and in setting up an efficient surveillance system for emerging/reemerging zoonosis. |
| Document Type: | Article |
| File Description: | application/pdf |
| Language: | English |
| ISSN: | 1567-1348 |
| DOI: | 10.1016/j.meegid.2011.02.003 |
| Access URL: | https://pubmed.ncbi.nlm.nih.gov/21320643 https://www.sciencedirect.com/science/article/pii/S1567134811000281 https://www.ncbi.nlm.nih.gov/pubmed/21320643 https://hdl.handle.net/20.500.11768/157070 https://doi.org/10.1016/j.meegid.2011.02.003 https://hdl.handle.net/2434/160535 https://doi.org/10.1016/j.meegid.2011.02.003 https://hdl.handle.net/11585/102239 https://doi.org/10.1016/j.meegid.2011.02.003 |
| Rights: | Elsevier TDM |
| Accession Number: | edsair.doi.dedup.....a5d95ca551cf7a47b545a4ecc69e58a8 |
| Database: | OpenAIRE |
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Nájsť tento článok vo Web of Science | Abstract: | Aim of this study was to reconstruct the temporal and spatial phylodynamics of WNV-1a, the genotype to which the majority of European/Mediterranean viral strains belongs, by using sequences retrieved from public databases. WNV-1a isolates segregated into two major clades: the recent West Mediterranean sequences formed a single monophyletic group within clade A. Clade B included sequences from East Mediterranean and America. Phylogeographic analysis suggested that WNV-1a probably originated in sub-Saharan Africa in the early XXth century, and then spread northwards since the late 1970s, via two routes: one crossing Eastern Mediterranean and the other the Western Mediterranean countries. Our data suggest that the circulation of the virus in a given geographical area usually precedes the onset of the outbreak by one year or more, and underline the importance of the spatial-temporal phylodynamics reconstruction in clarifying the recent epidemiology and in setting up an efficient surveillance system for emerging/reemerging zoonosis. |
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| ISSN: | 15671348 |
| DOI: | 10.1016/j.meegid.2011.02.003 |