Just do it! How performing an action enhances remembering in transient global amnesia
Saved in:
| Title: | Just do it! How performing an action enhances remembering in transient global amnesia |
|---|---|
| Authors: | Hainselin, Mathieu, Quinette, Peggy, Juskenaite, Aurelija, Desgranges, Béatrice, Martinaud, Olivier, de La Sayette, Vincent, Hannequin, Didier, Viader, Fausto, Eustache, Francis |
| Contributors: | Eustache, Francis, Neuropsychologie cognitive et neuroanatomie fonctionnelles de la mémoire humaine, Université de Caen Normandie (UNICAEN), Normandie Université (NU)-Normandie Université (NU)-École Pratique des Hautes Études (EPHE), Université Paris Sciences et Lettres (PSL)-Université Paris Sciences et Lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM), CHU Rouen, Normandie Université (NU), Service de Neurologie CHU Caen, Normandie Université (NU)-Normandie Université (NU)-CHU Caen, Normandie Université (NU)-Tumorothèque de Caen Basse-Normandie (TCBN)-Tumorothèque de Caen Basse-Normandie (TCBN), Génétique du cancer et des maladies neuropsychiatriques (GMFC), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), This work was supported by Caen University Hospital, as part of a clinical research project. INSERM managed the PhD funding of Mathieu Hainselin, provided by Lower Normandy Regional Council and the Vicq d'Azyr association. |
| Source: | Cortex. 50:192-199 |
| Publisher Information: | Elsevier BV, 2014. |
| Publication Year: | 2014 |
| Subject Terms: | Male, binding, MESH: Mental Recall, Enactment effect, MESH: Movement, Anxiety, Neuropsychological Tests, MESH: Stroop Test, 0302 clinical medicine, Amnesia, Transient Global, MESH: Memory, Transient Global, MESH: Aged, MESH: Middle Aged, 05 social sciences, MESH: Affect, MESH: Neuropsychological Tests, transient global amnesia, Statistical, Middle Aged, 3. Good health, Memory, Short-Term, Data Interpretation, Statistical, [SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Female, memory for action, Cues, Episodic, MESH: Amnesia, Memory, Episodic, Movement, 03 medical and health sciences, Memory, MESH: Trail Making Test, MESH: Analysis of Variance, Transient global amnesia, Humans, 0501 psychology and cognitive sciences, [SDV.NEU] Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC], Memory for action, Aged, Analysis of Variance, MESH: Data Interpretation, MESH: Humans, Trail Making Test, MESH: Anxiety, Self-performed task, enactment effect, Binding, MESH: Male, Affect, Short-Term, self-performed task, Mental Recall, Stroop Test, MESH: Female, MESH: Cues |
| Description: | Transient global amnesia (TGA) is a clinical syndrome characterized by the sudden onset of a massive episodic memory deficit that spares other cognitive functions. As such, it provides a unique human amnesia model for testing the enactment effect (i.e., better memory for performed actions than for verbally encoded sentences). Our main aim was to test whether the enactment effect is preserved in TGA patients, both to have a better understanding and to test the robustness of this effect in a massive amnesia. Object-action pairs were encoded under four conditions: verbal, experimenter-performed, and two enacted conditions (self-performed and self-performed with choice). We tested object-action pair retrieval using cued recall (CR) and recognition tasks, and source memory using a free recall task. We also assessed binding, executive functions, short-term memory, episodic memory, anxiety and mood. We run correlations to control for their putative effects on memory for action. Data were collected from 24 patients, 16 of whom were examined during the acute phase and eight the day-after, as well as from 18 healthy controls. The memory performances of the patients in the acute phase improved for both (i) the CR score, between the verbal, experimenter-performed and self-performed with choice conditions, and (ii) the total recognition score, between the verbal condition and the two enacted conditions. Correlations were found between self-performed task (SPT) enhancement and both the binding and anxiety. In spite of their severely impaired episodic memory, patients with TGA benefit from the enactment effect. These results are discussed in relation to the role of motor components and episodic integration in memory for actions. We suggest that enactment effect can be used in clinical practice and rehabilitation, possible even for patients with a massive memory impairment. |
| Document Type: | Article |
| File Description: | application/pdf |
| Language: | English |
| ISSN: | 0010-9452 |
| DOI: | 10.1016/j.cortex.2013.10.007 |
| Access URL: | https://www.hal.inserm.fr/inserm-00931659/file/CORTEX1090.pdf https://pubmed.ncbi.nlm.nih.gov/24268322 https://hal.archives-ouvertes.fr/inserm-00875494 https://www.ncbi.nlm.nih.gov/pubmed/24268322 https://www.sciencedirect.com/science/article/pii/S0010945213002529#! https://europepmc.org/article/MED/24268322 https://www.hal.inserm.fr/inserm-00875494/document https://www.sciencedirect.com/science/article/pii/S0010945213002529 https://inserm.hal.science/inserm-00875494v1 https://doi.org/10.1016/j.cortex.2013.10.007 https://inserm.hal.science/inserm-00875494v1/document |
| Rights: | Elsevier TDM |
| Accession Number: | edsair.doi.dedup.....9e5fe07d86f42fa0855866eb93d22b40 |
| Database: | OpenAIRE |
Full Text Finder 
Nájsť tento článok vo Web of Science | Abstract: | Transient global amnesia (TGA) is a clinical syndrome characterized by the sudden onset of a massive episodic memory deficit that spares other cognitive functions. As such, it provides a unique human amnesia model for testing the enactment effect (i.e., better memory for performed actions than for verbally encoded sentences). Our main aim was to test whether the enactment effect is preserved in TGA patients, both to have a better understanding and to test the robustness of this effect in a massive amnesia. Object-action pairs were encoded under four conditions: verbal, experimenter-performed, and two enacted conditions (self-performed and self-performed with choice). We tested object-action pair retrieval using cued recall (CR) and recognition tasks, and source memory using a free recall task. We also assessed binding, executive functions, short-term memory, episodic memory, anxiety and mood. We run correlations to control for their putative effects on memory for action. Data were collected from 24 patients, 16 of whom were examined during the acute phase and eight the day-after, as well as from 18 healthy controls. The memory performances of the patients in the acute phase improved for both (i) the CR score, between the verbal, experimenter-performed and self-performed with choice conditions, and (ii) the total recognition score, between the verbal condition and the two enacted conditions. Correlations were found between self-performed task (SPT) enhancement and both the binding and anxiety. In spite of their severely impaired episodic memory, patients with TGA benefit from the enactment effect. These results are discussed in relation to the role of motor components and episodic integration in memory for actions. We suggest that enactment effect can be used in clinical practice and rehabilitation, possible even for patients with a massive memory impairment. |
|---|---|
| ISSN: | 00109452 |
| DOI: | 10.1016/j.cortex.2013.10.007 |