Word learning reveals white matter plasticity in preschool children
Uloženo v:
| Název: | Word learning reveals white matter plasticity in preschool children |
|---|---|
| Autoři: | Clara E. M. Ekerdt, Clara Kühn, Alfred Anwander, Jens Brauer, Angela D. Friederici |
| Zdroj: | Brain Struct Funct Brain Structure and Function, 225, 2, pp. 607-619 Brain Structure & Function |
| Informace o vydavateli: | Springer Science and Business Media LLC, 2020. |
| Rok vydání: | 2020 |
| Témata: | Male, Neuronal Plasticity, 4. Education, 05 social sciences, Female [MeSH], Development, Humans [MeSH], White Matter/anatomy, Brain/physiology [MeSH], White Matter/physiology [MeSH], Original Article, Learning/physiology [MeSH], White matter, Brain/anatomy, Male [MeSH], Language acquisition, Reading [MeSH], Plasticity, Diffusion Magnetic Resonance Imaging [MeSH], Neuronal Plasticity [MeSH], Child, Preschool [MeSH], Diffusion tensor imaging (DTI), Language Development [MeSH], Brain, Language Development, White Matter, Radboudumc 13: Stress-related disorders DCMN: Donders Center for Medical Neuroscience, 03 medical and health sciences, Diffusion Magnetic Resonance Imaging, 0302 clinical medicine, Reading, 130 000 Cognitive Neurology & Memory, Child, Preschool, Humans, Learning, Female, 0501 psychology and cognitive sciences, Cognitive Neuroscience - Radboud University Medical Center |
| Popis: | Word learning plays a central role in language development and is a key predictor for later academic success. The underlying neural basis of successful word learning in children is still unknown. Here, we took advantage of the opportunity afforded by diffusion-weighted magnetic resonance imaging to investigate neural plasticity in the white matter of typically developing preschool children as they learn words. We demonstrate that after 3 weeks of word learning, children showed significantly larger increases of fractional anisotropy (FA) in the left precentral white matter compared to two control groups. Average training accuracy was correlated with FA change in the white matter underlying the left dorsal postcentral gyrus, with children who learned more slowly showing larger FA increases in this region. Moreover, we found that the status of white matter in the left middle temporal gyrus, assumed to support semantic processes, is predictive for early stages of word learning. Our findings provide the first evidence for white matter plasticity following word learning in preschool children. The present results on learning novel words in children point to a key involvement of the left fronto-parietal fiber connection, known to be implicated in top-down attention as well as working memory. While working memory and attention have been discussed to participate in word learning in children, our training study provides evidence that the neural structure supporting these cognitive processes plays a direct role in word learning. |
| Druh dokumentu: | Article Other literature type |
| Popis souboru: | application/pdf |
| Jazyk: | English |
| ISSN: | 1863-2661 1863-2653 |
| DOI: | 10.1007/s00429-020-02024-7 |
| Přístupová URL adresa: | https://link.springer.com/content/pdf/10.1007/s00429-020-02024-7.pdf https://pubmed.ncbi.nlm.nih.gov/32072249 https://repository.ubn.ru.nl/handle/2066/220593 https://www.ncbi.nlm.nih.gov/pubmed/32072249 https://pure.mpg.de/pubman/item/item_3185555_4/component/file_3218865/Ekerdt_2020.pdf https://www.narcis.nl/publication/RecordID/oai%3Arepository.ubn.ru.nl%3A2066%2F220593 https://link.springer.com/content/pdf/10.1007/s00429-020-02024-7.pdf https://pubmed.ncbi.nlm.nih.gov/32072249/ https://repository.ubn.ru.nl//bitstream/handle/2066/220593/220593.pdf https://hdl.handle.net/2066/220593 http://hdl.handle.net/21.11116/0000-0006-0922-A http://hdl.handle.net/21.11116/0000-0005-724C-6 https://repository.publisso.de/resource/frl:6467368 |
| Rights: | CC BY |
| Přístupové číslo: | edsair.doi.dedup.....9e2b73310d2942f8a379b57cb02137d0 |
| Databáze: | OpenAIRE |
Full Text Finder 
Nájsť tento článok vo Web of Science | Abstrakt: | Word learning plays a central role in language development and is a key predictor for later academic success. The underlying neural basis of successful word learning in children is still unknown. Here, we took advantage of the opportunity afforded by diffusion-weighted magnetic resonance imaging to investigate neural plasticity in the white matter of typically developing preschool children as they learn words. We demonstrate that after 3 weeks of word learning, children showed significantly larger increases of fractional anisotropy (FA) in the left precentral white matter compared to two control groups. Average training accuracy was correlated with FA change in the white matter underlying the left dorsal postcentral gyrus, with children who learned more slowly showing larger FA increases in this region. Moreover, we found that the status of white matter in the left middle temporal gyrus, assumed to support semantic processes, is predictive for early stages of word learning. Our findings provide the first evidence for white matter plasticity following word learning in preschool children. The present results on learning novel words in children point to a key involvement of the left fronto-parietal fiber connection, known to be implicated in top-down attention as well as working memory. While working memory and attention have been discussed to participate in word learning in children, our training study provides evidence that the neural structure supporting these cognitive processes plays a direct role in word learning. |
|---|---|
| ISSN: | 18632661 18632653 |
| DOI: | 10.1007/s00429-020-02024-7 |