Long-term follow-up of non‑neurologic and neurologic complications after complex adult spinal deformity surgery: results from the Scoli-RISK-1 study

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Titel: Long-term follow-up of non‑neurologic and neurologic complications after complex adult spinal deformity surgery: results from the Scoli-RISK-1 study
Autoren: Meghan Cerpa, Scott L. Zuckerman, Lawrence G. Lenke, Leah Y. Carreon, Kenneth M. C. Cheung, Michael P. Kelly, Michael G. Fehlings, Christopher P. Ames, Oheneba Boachie-Adjei, Mark B. Dekutoski, Khaled M. Kebaish, Stephen J. Lewis, Yukihiro Matsuyama, Ferran Pellisé, Yong Qiu, Frank J. Schwab, Justin S. Smith, Christopher I. Shaffrey
Weitere Verfasser: Institut Català de la Salut, [Cerpa M, Lenke LG] Department of Orthopaedic Surgery, New York Presbyterian, The Daniel and Jane Och Spine Hospital, Columbia University Medical Center, Broadway, New York, NY, USA. [Zuckerman SL] Vanderbilt Univerity Medical Center, Nashville, TN, USA. [Carreon LY] Norton Leatherman Spine Center, Louisville, KY, USA. [Cheung KMC] Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong. [Kelly MP] Rady’s Children’s Hospital, San Diego, CA, USA. [Pellisé F] Vall d’Hebron Hospital Universitari, Barcelona, Spain, Vall d'Hebron Barcelona Hospital Campus
Quelle: Scientia
Scientia. Dipòsit d'Informació Digital del Departament de Salut
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Verlagsinformationen: Springer Science and Business Media LLC, 2025.
Publikationsjahr: 2025
Schlagwörter: NAMED GROUPS::Persons::Age Groups::Adult, Otros calificadores::Otros calificadores::Otros calificadores::/cirugía, Sistema nerviós - Malalties, ENFERMEDADES::enfermedades del sistema nervioso, Escoliosi - Cirurgia - Complicacions, DISEASES::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Postoperative Complications, ENFERMEDADES::enfermedades musculoesqueléticas::enfermedades óseas::enfermedades de la columna vertebral::desviaciones de la columna vertebral::escoliosis, Adults, DISEASES::Musculoskeletal Diseases::Bone Diseases::Spinal Diseases::Spinal Curvatures::Scoliosis, Other subheadings::Other subheadings::Other subheadings::/surgery, DENOMINACIONES DE GRUPOS::personas::Grupos de Edad::adulto, DISEASES::Nervous System Diseases, ENFERMEDADES::afecciones patológicas, signos y síntomas::procesos patológicos::complicaciones posoperatorias
Beschreibung: To report all complications that occurred during the 2 to 5-year postoperative period, describe reoperations during this time period, and compare patients who did and did not have major, surgery-related complications and/or reoperations during this time period.The Scoli-RISK-1 study enrolled 272 ASD patients undergoing surgery from 15 centers. Inclusion criteria were Cobb angle of > 80°, corrective osteotomy for congenital/revision deformity, and/or 3-column osteotomy. At each follow-up visit, any neurologic or non-neurologic adverse event(AE) was documented & categorized.77 patients had a minimum 5-year follow-up. 35 surgery-related AE's occurred during the 2 to 5-year period in 25(32.5%) patients. 23/35(65.7%) major, surgery-related complications occurred in 17 patients, 22/35(62.9%) requiring reoperations in 16 patients. Rod fracture and/or pseudarthrosis was the most common complication. The most common minor, surgery-related complication was asymptomatic rod fractures with no alignment changes. Four neurological complications were reported, one of which did not require reoperation. One death occurred at 6.1 years postoperative after multiple reoperations for mechanical complications. 14/17(82.4%) patients with major, surgery-related complication had a preceding AE during the initial 2-year postoperative period. 53 non-surgery-related AEs occurred in 21(27.3%) patients with musculoskeletal(37.7%) occurring most often. No differences were observed in ODI or SRS-22r in those with/without major surgery-related complications or those with/without reoperation.During the study period, 25(32.5%) patients experienced 35 surgery-related complications, of which 23(65.7%) were major. Rod fracture with pseudarthrosis was the most common major, surgery-related complication. Neurologic complications were not found to be major drivers of reoperation. Surprisingly, PROs were similar in those with/without a major, surgery-related complication during the study period. This work has been presented as a podium presentation at the 55th Scoliosis Research Society annual meeting, Sep 9-13, 2020.
Publikationsart: Article
Dateibeschreibung: application/pdf
Sprache: English
ISSN: 1432-0932
0940-6719
DOI: 10.1007/s00586-025-08683-6
Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/39937191
http://hdl.handle.net/11351/13350
Rights: CC BY NC ND
Dokumentencode: edsair.doi.dedup.....9d8099c0d890900c4ae84cb7ced9724a
Datenbank: OpenAIRE
Beschreibung
Abstract:To report all complications that occurred during the 2 to 5-year postoperative period, describe reoperations during this time period, and compare patients who did and did not have major, surgery-related complications and/or reoperations during this time period.The Scoli-RISK-1 study enrolled 272 ASD patients undergoing surgery from 15 centers. Inclusion criteria were Cobb angle of > 80°, corrective osteotomy for congenital/revision deformity, and/or 3-column osteotomy. At each follow-up visit, any neurologic or non-neurologic adverse event(AE) was documented & categorized.77 patients had a minimum 5-year follow-up. 35 surgery-related AE's occurred during the 2 to 5-year period in 25(32.5%) patients. 23/35(65.7%) major, surgery-related complications occurred in 17 patients, 22/35(62.9%) requiring reoperations in 16 patients. Rod fracture and/or pseudarthrosis was the most common complication. The most common minor, surgery-related complication was asymptomatic rod fractures with no alignment changes. Four neurological complications were reported, one of which did not require reoperation. One death occurred at 6.1 years postoperative after multiple reoperations for mechanical complications. 14/17(82.4%) patients with major, surgery-related complication had a preceding AE during the initial 2-year postoperative period. 53 non-surgery-related AEs occurred in 21(27.3%) patients with musculoskeletal(37.7%) occurring most often. No differences were observed in ODI or SRS-22r in those with/without major surgery-related complications or those with/without reoperation.During the study period, 25(32.5%) patients experienced 35 surgery-related complications, of which 23(65.7%) were major. Rod fracture with pseudarthrosis was the most common major, surgery-related complication. Neurologic complications were not found to be major drivers of reoperation. Surprisingly, PROs were similar in those with/without a major, surgery-related complication during the study period. This work has been presented as a podium presentation at the 55th Scoliosis Research Society annual meeting, Sep 9-13, 2020.
ISSN:14320932
09406719
DOI:10.1007/s00586-025-08683-6