Three-dimensional and four-dimensional flow assessment in congenital heart disease

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Název: Three-dimensional and four-dimensional flow assessment in congenital heart disease
Autoři: Evangeline Warmerdam, Gregor J Krings, Tim Leiner, Heynric B Grotenhuis
Přispěvatelé: Cardiologie onderzoek 1, Cardiologie, Cardiologie patientenzorg, Cluster A, Circulatory Health, Researchgr. Cardiovasculaire Radiologie, Child Health
Zdroj: Heart. 106:421-426
Informace o vydavateli: BMJ, 2019.
Rok vydání: 2019
Témata: Heart Defects, Congenital, 2. Zero hunger, Heart Defects, Congenital/diagnostic imaging, Cardiac Imaging Techniques/methods, Hemodynamics, Review, Magnetic Resonance Imaging, 3. Good health, Cardiac Imaging Techniques, 03 medical and health sciences, Imaging, Three-Dimensional, 0302 clinical medicine, Regional Blood Flow, Journal Article, Hydrodynamics, Humans, Cardiology and Cardiovascular Medicine
Popis: Congenital heart disease (CHD) is the most common form of congenital defects, with an incidence of 8 per 1000 births. Due to major advances in diagnostics, perioperative care and surgical techniques, the survival rate of patients with CHD has improved dramatically. Conversely, although 70%–95% of infants with CHD survive into adulthood, the rate of long-term morbidity, which often requires (repeat) intervention, has increased. Recently, the role of altered haemodynamics in cardiac development and CHD has become a subject of interest. Patients with CHD often have abnormal blood flow patterns, either due to the primary cardiac defect or as a consequence of the surgical intervention(s). Research suggests that these abnormal blood flow patterns may contribute to diminished cardiac and vascular function. Serial assessment of haemodynamic parameters in patients with CHD may allow for improved understanding of the often complex haemodynamics in these patients and thereby potentially guide the timing and nature of interventions with the aim of preventing progression of cardiovascular deterioration. In this article we will discuss two novel non-invasive four-dimensional (4D) techniques to evaluate cardiovascular haemodynamics: 4D-flow cardiac magnetic resonance and computational fluid dynamics. This review focuses on the additional value of these two modalities in the evaluation of patients with CHD with abnormal flow patterns, who could benefit from advanced haemodynamic evaluation: patients with coarctation of the aorta, bicuspid aortic valve, tetralogy of Fallot and patients after Fontan palliation.
Druh dokumentu: Article
Popis souboru: application/pdf
Jazyk: English
ISSN: 1468-201X
1355-6037
DOI: 10.1136/heartjnl-2019-315797
Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/31857355
https://www.narcis.nl/publication/RecordID/oai%3Adspace.library.uu.nl%3A1874%2F394920
https://pubmed.ncbi.nlm.nih.gov/31857355/
https://heart.bmj.com/content/heartjnl/early/2019/12/19/heartjnl-2019-315797.full.pdf
https://heart.bmj.com/content/early/2019/12/19/heartjnl-2019-315797
https://heart.bmj.com/content/106/6/421
http://dspace.library.uu.nl/handle/1874/394920
https://dspace.library.uu.nl/handle/1874/394920
Přístupové číslo: edsair.doi.dedup.....9a79a650b0175d4e9170636a6f0d7f31
Databáze: OpenAIRE
Popis
Abstrakt:Congenital heart disease (CHD) is the most common form of congenital defects, with an incidence of 8 per 1000 births. Due to major advances in diagnostics, perioperative care and surgical techniques, the survival rate of patients with CHD has improved dramatically. Conversely, although 70%–95% of infants with CHD survive into adulthood, the rate of long-term morbidity, which often requires (repeat) intervention, has increased. Recently, the role of altered haemodynamics in cardiac development and CHD has become a subject of interest. Patients with CHD often have abnormal blood flow patterns, either due to the primary cardiac defect or as a consequence of the surgical intervention(s). Research suggests that these abnormal blood flow patterns may contribute to diminished cardiac and vascular function. Serial assessment of haemodynamic parameters in patients with CHD may allow for improved understanding of the often complex haemodynamics in these patients and thereby potentially guide the timing and nature of interventions with the aim of preventing progression of cardiovascular deterioration. In this article we will discuss two novel non-invasive four-dimensional (4D) techniques to evaluate cardiovascular haemodynamics: 4D-flow cardiac magnetic resonance and computational fluid dynamics. This review focuses on the additional value of these two modalities in the evaluation of patients with CHD with abnormal flow patterns, who could benefit from advanced haemodynamic evaluation: patients with coarctation of the aorta, bicuspid aortic valve, tetralogy of Fallot and patients after Fontan palliation.
ISSN:1468201X
13556037
DOI:10.1136/heartjnl-2019-315797