Dynamische Peptidvesikel als Vorstufe synthetischer Zellen?

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Bibliographic Details
Title: Dynamische Peptidvesikel als Vorstufe synthetischer Zellen?
Authors: Pirzer, Tobias
Source: BIOspektrum. 27:604-606
Publisher Information: Springer Science and Business Media LLC, 2021.
Publication Year: 2021
Subject Terms: 0301 basic medicine, 0303 health sciences, 03 medical and health sciences, Wissenschaft Methoden, Life Sciences, general, Biochemistry, general, Human Genetics, Microbiology, Pharmacology/Toxicology, ddc
Description: Compartmentalization and spatial control of biochemical reactions are essential for the creation of artificial cellular systems. But it is notoriously difficult to implement reaction networks and membrane building blocks in vitro. In this article, we briefly highlight our work on the formation of peptide-based vesicles as artificial cell precursors with a size of up to 100 µm These cell mimics are able to produce RNA aptamers and proteins at the inside, and are further capable of strong growth.
Document Type: Article
File Description: application/pdf
Language: German
ISSN: 1868-6249
0947-0867
DOI: 10.1007/s12268-021-1647-8
Access URL: https://link.springer.com/content/pdf/10.1007/s12268-021-1647-8.pdf
https://link.springer.com/article/10.1007/s12268-021-1647-8
https://link.springer.com/content/pdf/10.1007/s12268-021-1647-8.pdf
https://mediatum.ub.tum.de/doc/1704869/document.pdf
Rights: CC BY
Accession Number: edsair.doi.dedup.....99484e6c207835ff7540221c419bdc2f
Database: OpenAIRE
Description
Abstract:Compartmentalization and spatial control of biochemical reactions are essential for the creation of artificial cellular systems. But it is notoriously difficult to implement reaction networks and membrane building blocks in vitro. In this article, we briefly highlight our work on the formation of peptide-based vesicles as artificial cell precursors with a size of up to 100 µm These cell mimics are able to produce RNA aptamers and proteins at the inside, and are further capable of strong growth.
ISSN:18686249
09470867
DOI:10.1007/s12268-021-1647-8