Prevalence and risk factors of moderate to severe obstructive sleep apnea syndrome in major depression: a observational and retrospective study on 703 subjects
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| Title: | Prevalence and risk factors of moderate to severe obstructive sleep apnea syndrome in major depression: a observational and retrospective study on 703 subjects |
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| Authors: | Hein, Matthieu, Lanquart, Jean Pol, Loas, Gwenolé, Hubain, Philippe, Linkowski, Paul |
| Source: | BMC Pulm Med BMC Pulmonary Medicine, Vol 17, Iss 1, Pp 1-10 (2017) BMC pulmonary medicine, 17 (1 |
| Publisher Information: | Springer Science and Business Media LLC, 2017. |
| Publication Year: | 2017 |
| Subject Terms: | Adult, Male, Sleep Apnea, Obstructive apnea syndrome, Snoring -- epidemiology, Obstructive -- epidemiology, Comorbidity, Disorders of Excessive Somnolence, Severity of Illness Index, Body Mass Index, Diseases of the respiratory system, 03 medical and health sciences, Sex Factors, 0302 clinical medicine, Sleep Initiation and Maintenance Disorders -- epidemiology, Risk Factors, Prevalence, Depression -- epidemiology, Disorders of Excessive Somnolence -- epidemiology, Major depression, Humans, Metabolic Syndrome -- epidemiology, Retrospective Studies, Metabolic Syndrome, Sleep Apnea, Obstructive, RC705-779, Depression, Age Factors, C-Reactive Protein -- metabolism, Middle Aged, Ferritins -- blood, 3. Good health, Sleep Apnea, Obstructive -- epidemiology, C-Reactive Protein, Risk factors, Ferritins, Female, Pneumologie, Sleep, Research Article |
| Description: | Several studies have investigated the prevalence and risk factors of depression in subjects with obstructive sleep apnea syndrome. However, few studies have investigated the prevalence and risk factors for obstructive sleep apnea syndrome in major depression. The aim of this study was to examine the prevalence and risk factors of moderate to severe obstructive sleep apnea syndrome in a large sample of individuals with major depression.Data from 703 individuals with major depression recruited from the research database of the sleep laboratory of the Erasme Hospital were analysed. An apnea-hypopnea index of ≥15 events per hour was used as cut-off score for moderate to severe obstructive sleep apnea syndrome. Logistic regression analyses were conducted to examine clinical and demographic risk factors of moderate to severe obstructive sleep apnea syndrome in major depression.The prevalence of moderate to severe obstructive sleep apnea syndrome in major depression is 13.94%. Multivariate logistic regression analysis revealed that male gender, snoring, excessive daytime sleepiness, lower insomnia complaint, presence of metabolic syndrome, age ≥ 50 years, BMI >30 kg/m2, ferritin >300 μg/L, CRP >7 mg/L and duration of sleep ≥8 h were significant risk factors of moderate to severe obstructive sleep apnea syndrome in major depression.Moderate to severe obstructive sleep apnea syndrome is a common pathology in major depression. The identification of these different risk factors advances a new perspective for more effective screening of moderate to severe obstructive sleep apnea syndrome in major depression. |
| Document Type: | Article Other literature type |
| File Description: | 1 full-text file(s): application/pdf |
| Language: | English |
| ISSN: | 1471-2466 |
| DOI: | 10.1186/s12890-017-0522-3 |
| Access URL: | https://bmcpulmmed.biomedcentral.com/track/pdf/10.1186/s12890-017-0522-3 https://pubmed.ncbi.nlm.nih.gov/29202829 https://doaj.org/article/bb7603d44b2246b18b445763252d9fcc https://0-bmcpulmmed-biomedcentral-com.brum.beds.ac.uk/articles/10.1186/s12890-017-0522-3 https://link.springer.com/article/10.1186/s12890-017-0522-3 https://www.ncbi.nlm.nih.gov/pubmed/29202829 https://bmcpulmmed.biomedcentral.com/articles/10.1186/s12890-017-0522-3 http://europepmc.org/articles/PMC5715980 https://pubmed.ncbi.nlm.nih.gov/29202829/ http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/263228 |
| Rights: | CC BY |
| Accession Number: | edsair.doi.dedup.....8d893b2cc9261f9fcc3f097bf9abacbc |
| Database: | OpenAIRE |
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Nájsť tento článok vo Web of Science | Abstract: | Several studies have investigated the prevalence and risk factors of depression in subjects with obstructive sleep apnea syndrome. However, few studies have investigated the prevalence and risk factors for obstructive sleep apnea syndrome in major depression. The aim of this study was to examine the prevalence and risk factors of moderate to severe obstructive sleep apnea syndrome in a large sample of individuals with major depression.Data from 703 individuals with major depression recruited from the research database of the sleep laboratory of the Erasme Hospital were analysed. An apnea-hypopnea index of ≥15 events per hour was used as cut-off score for moderate to severe obstructive sleep apnea syndrome. Logistic regression analyses were conducted to examine clinical and demographic risk factors of moderate to severe obstructive sleep apnea syndrome in major depression.The prevalence of moderate to severe obstructive sleep apnea syndrome in major depression is 13.94%. Multivariate logistic regression analysis revealed that male gender, snoring, excessive daytime sleepiness, lower insomnia complaint, presence of metabolic syndrome, age ≥ 50 years, BMI >30 kg/m2, ferritin >300 μg/L, CRP >7 mg/L and duration of sleep ≥8 h were significant risk factors of moderate to severe obstructive sleep apnea syndrome in major depression.Moderate to severe obstructive sleep apnea syndrome is a common pathology in major depression. The identification of these different risk factors advances a new perspective for more effective screening of moderate to severe obstructive sleep apnea syndrome in major depression. |
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| ISSN: | 14712466 |
| DOI: | 10.1186/s12890-017-0522-3 |