Human health in relation to exposure to solar ultraviolet radiation under changing stratospheric ozone and climate
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| Název: | Human health in relation to exposure to solar ultraviolet radiation under changing stratospheric ozone and climate |
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| Autoři: | Y Takizawa, Seyhan Yazar, Lesley E. Rhodes, Craig Sinclair, Mary Norval, Rachel E. Neale, Antony R. Young, F.R. de Gruijl, Robyn M. Lucas |
| Zdroj: | Lucas, R M, Yazar, S, Young, A R, Norval, M, de Gruijl, F R, Takizawa, Y, Rhodes, L E, Sinclair, C A & Neale, R E 2019, 'Human health in relation to exposure to solar ultraviolet radiation under changing stratospheric ozone and climate', Photochemical and Photobiological Sciences, vol. 18, no. 3, pp. 641-680. https://doi.org/10.1039/c8pp90060d |
| Informace o vydavateli: | Springer Science and Business Media LLC, 2019. |
| Rok vydání: | 2019 |
| Témata: | Stratospheric Ozone/analysis, Skin Neoplasms, DNA Damage/radiation effects, Lydia Becker Institute, Eye Diseases, Ultraviolet Rays, Climate Change, Skin Diseases, Skin Diseases/etiology, Immunity/radiation effects, 03 medical and health sciences, 0302 clinical medicine, Ultraviolet Rays/adverse effects, Humans, Skin Neoplasms/etiology, Physical and Theoretical Chemistry, Vitamin D, Vitamin D/analysis, Stratospheric Ozone, Immunity, Vitamin D Deficiency, 3. Good health, Eye Diseases/etiology, Health, 13. Climate action, Vitamin D Deficiency/etiology, Sunlight, 1606 Physical and Theoretical Chemistry, ResearchInstitutes_Networks_Beacons/lydia_becker_institute_of_immunology_and_inflammation, name=Lydia Becker Institute, DNA Damage |
| Popis: | The Montreal Protocol has limited increases in the UV-B (280-315 nm) radiation reaching the Earth's surface as a result of depletion of stratospheric ozone. Nevertheless, the incidence of skin cancers continues to increase in most light-skinned populations, probably due mainly to risky sun exposure behaviour. In locations with strong sun protection programs of long duration, incidence is now reducing in younger age groups. Changes in the epidemiology of UV-induced eye diseases are less clear, due to a lack of data. Exposure to UV radiation plays a role in the development of cataracts, pterygium and possibly age-related macular degeneration; these are major causes of visual impairment world-wide. Photodermatoses and phototoxic reactions to drugs are not uncommon; management of the latter includes recognition of the risks by the prescribing physician. Exposure to UV radiation has benefits for health through the production of vitamin D in the skin and modulation of immune function. The latter has benefits for skin diseases such as psoriasis and possibly for systemic autoimmune diseases such as multiple sclerosis. The health risks of sun exposure can be mitigated through appropriate sun protection, such as clothing with both good UV-blocking characteristics and adequate skin coverage, sunglasses, shade, and sunscreen. New sunscreen preparations provide protection against a broader spectrum of solar radiation, but it is not clear that this has benefits for health. Gaps in knowledge make it difficult to derive evidence-based sun protection advice that balances the risks and benefits of sun exposure. |
| Druh dokumentu: | Article |
| Popis souboru: | application/vnd.openxmlformats-officedocument.wordprocessingml.document; application/pdf |
| Jazyk: | English |
| ISSN: | 1474-9092 1474-905X |
| DOI: | 10.1039/c8pp90060d |
| Přístupová URL adresa: | https://pubmed.ncbi.nlm.nih.gov/30810559 https://pubs.rsc.org/en/content/articlelanding/2019/pp/c8pp90060d https://link.springer.com/article/10.1039/c8pp90060d https://research-repository.uwa.edu.au/en/publications/human-health-in-relation-to-exposure-to-solar-ultraviolet-radiati https://openresearch-repository.anu.edu.au/handle/1885/165186 https://espace.library.uq.edu.au/view/UQ:6e76a8e https://pubmed.ncbi.nlm.nih.gov/30810559/ https://pure.manchester.ac.uk/ws/files/87032707/EEAP_CH2_2018_11_18_RL.DOCX http://www.scopus.com/inward/record.url?scp=85062876362&partnerID=8YFLogxK https://doi.org/10.1039/c8pp90060d https://research.manchester.ac.uk/en/publications/0ec804f5-ce55-4a28-b930-dd7e8f0fb610 http://www.mendeley.com/research/human-health-relation-exposure-solar-ultraviolet-radiation-under-changing-stratospheric-ozone-climat |
| Rights: | Springer TDM publisher-specific, author manuscript |
| Přístupové číslo: | edsair.doi.dedup.....8971b098655b4a6047f4de35337a7726 |
| Databáze: | OpenAIRE |
Nájsť tento článok vo Web of Science | Abstrakt: | The Montreal Protocol has limited increases in the UV-B (280-315 nm) radiation reaching the Earth's surface as a result of depletion of stratospheric ozone. Nevertheless, the incidence of skin cancers continues to increase in most light-skinned populations, probably due mainly to risky sun exposure behaviour. In locations with strong sun protection programs of long duration, incidence is now reducing in younger age groups. Changes in the epidemiology of UV-induced eye diseases are less clear, due to a lack of data. Exposure to UV radiation plays a role in the development of cataracts, pterygium and possibly age-related macular degeneration; these are major causes of visual impairment world-wide. Photodermatoses and phototoxic reactions to drugs are not uncommon; management of the latter includes recognition of the risks by the prescribing physician. Exposure to UV radiation has benefits for health through the production of vitamin D in the skin and modulation of immune function. The latter has benefits for skin diseases such as psoriasis and possibly for systemic autoimmune diseases such as multiple sclerosis. The health risks of sun exposure can be mitigated through appropriate sun protection, such as clothing with both good UV-blocking characteristics and adequate skin coverage, sunglasses, shade, and sunscreen. New sunscreen preparations provide protection against a broader spectrum of solar radiation, but it is not clear that this has benefits for health. Gaps in knowledge make it difficult to derive evidence-based sun protection advice that balances the risks and benefits of sun exposure. |
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| ISSN: | 14749092 1474905X |
| DOI: | 10.1039/c8pp90060d |