Proteomics of Hepatocellular Carcinoma: Serum Vimentin As a Surrogate Marker for Small Tumors (≤2 cm)

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Názov: Proteomics of Hepatocellular Carcinoma: Serum Vimentin As a Surrogate Marker for Small Tumors (≤2 cm)
Autori: Sun, S., Poon, R.T.P., Lee, N.P., Yeung, C., Chan, K.L., Ng, I.O.L., Day, P.J.R., Luk, J.M.
Prispievatelia: PHARMACOLOGY
Zdroj: Sun, S, Poon, R T P, Lee, N P, Yeung, C, Chan, K L, Ng, I O L, Day, P J R & Luk, J M 2010, 'Proteomics of hepatocellular carcinoma: Serum vimentin as a surrogate marker for small tumors (≤2 cm)', Journal of Proteome Research, vol. 9, no. 4, pp. 1923-1930. https://doi.org/10.1021/pr901085z
Informácie o vydavateľovi: American Chemical Society (ACS), 2010.
Rok vydania: 2010
Predmety: Adult, Male, Proteomics, 0301 basic medicine, Tumor detection, Carcinoma, Hepatocellular, Vimentin - blood, Proteomics - methods, AFP, Enzyme-Linked Immunosorbent Assay, Sensitivity and Specificity, Tumor Markers, Biological - blood, Cancer screening, Cohort Studies, Hepatocellular - blood - diagnosis - pathology, 03 medical and health sciences, Carcinoma, Hepatocellular - blood - diagnosis - pathology, Cell Line, Tumor, Biological - blood, Biomarkers, Tumor, Humans, Vimentin, Liver Neoplasms - blood - diagnosis - pathology, HCC, Tumor Markers, Aged, 0303 health sciences, Carcinoma, Liver Neoplasms, Biomarker, Tumor size, Middle Aged, 3. Good health, Early Diagnosis, Area Under Curve, Female
Popis: Small hepatocellular carcinomas (HCCs) can be effectively cured by surgery with good clinical outcomes. However, the conventional AFP marker is ineffective in detecting small tumors. Here we employed a proteomic profiling approach to identify a candidate marker for HCC (
Druh dokumentu: Article
Jazyk: English
ISSN: 1535-3907
1535-3893
DOI: 10.1021/pr901085z
Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/20121168
https://research.manchester.ac.uk/en/publications/55a9167d-f10a-4fa0-bb4f-c562d337f9f6
https://doi.org/10.1021/pr901085z
http://europepmc.org/abstract/MED/20121168
https://www.escholar.manchester.ac.uk/uk-ac-man-scw:114729
https://pubs.acs.org/doi/pdf/10.1021/pr901085z
https://pubs.acs.org/doi/abs/10.1021/pr901085z
https://www.research.manchester.ac.uk/portal/en/publications/proteomics-of-hepatocellular-carcinoma-serum-vimentin-as-a-surrogate-marker-for-small-tumors-2-cm(55a9167d-f10a-4fa0-bb4f-c562d337f9f6).html
http://www.ncbi.nlm.nih.gov/pubmed/20121168
http://hdl.handle.net/10722/88478
Prístupové číslo: edsair.doi.dedup.....87c3277cd552d847d931bd37fae07643
Databáza: OpenAIRE
Popis
Abstrakt:Small hepatocellular carcinomas (HCCs) can be effectively cured by surgery with good clinical outcomes. However, the conventional AFP marker is ineffective in detecting small tumors. Here we employed a proteomic profiling approach to identify a candidate marker for HCC (
ISSN:15353907
15353893
DOI:10.1021/pr901085z