Engineered yeasts and lignocellulosic biomaterials: shaping a new dimension for biorefinery and global bioeconomy: shaping a new dimension for biorefinery and global bioeconomy
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| Název: | Engineered yeasts and lignocellulosic biomaterials: shaping a new dimension for biorefinery and global bioeconomy: shaping a new dimension for biorefinery and global bioeconomy |
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| Autoři: | Asemoloye, Michael Dare, Bello, Tunde Sheriffdeen, Oladoye, Peter Olusakin, Remilekun Gbadamosi, Muideen, Babarinde, Segun Oladiran, Ebenezer Adebami, Gboyega, Olowe, Olumayowa Mary, Temporiti, Marta Elisabetta Eleonora, Wanek, Wolfgang, Marchisio, Mario Andrea |
| Zdroj: | Bioengineered |
| Informace o vydavateli: | Informa UK Limited, 2023. |
| Rok vydání: | 2023 |
| Témata: | Yeasts/genetics, 106022 Mikrobiologie, Biotechnology/methods, Bioengineering, Review Article, Saccharomyces cerevisiae, Lignin, Lignin/metabolism, synthetic yeasts, biorefineries, Saccharomyces cerevisiae/metabolism, Metabolic Engineering, 106026 Ökosystemforschung, Yeasts, Biofuels, 8. Economic growth, 106022 Microbiology, lignocellulosic materials, metabolic pathways, Biomass, 106026 Ecosystem research, bioeconomy, Biotechnology |
| Popis: | The next milestone of synthetic biology research relies on the development of customized microbes for specific industrial purposes. Metabolic pathways of an organism, for example, depict its chemical repertoire and its genetic makeup. If genes controlling such pathways can be identified, scientists can decide to enhance or rewrite them for different purposes depending on the organism and the desired metabolites. The lignocellulosic biorefinery has achieved good progress over the past few years with potential impact on global bioeconomy. This principle aims to produce different bio-based products like biochemical(s) or biofuel(s) from plant biomass under microbial actions. Meanwhile, yeasts have proven very useful for different biotechnological applications. Hence, their potentials in genetic/metabolic engineering can be fully explored for lignocellulosic biorefineries. For instance, the secretion of enzymes above the natural limit (aided by genetic engineering) would speed-up the down-line processes in lignocellulosic biorefineries and the cost. Thus, the next milestone would greatly require the development of synthetic yeasts with much more efficient metabolic capacities to achieve basic requirements for particular biorefinery. This review gave comprehensive overview of lignocellulosic biomaterials and their importance in bioeconomy. Many researchers have demonstrated the engineering of several ligninolytic enzymes in heterologous yeast hosts. However, there are still many factors needing to be well understood like the secretion time, titter value, thermal stability, pH tolerance, and reactivity of the recombinant enzymes. Here, we give a detailed account of the potentials of engineered yeasts being discussed, as well as the constraints associated with their development and applications. Metabolic pathways of an organism depict its chemical repertoire and its genetic makeup.Autonomous synthetic microbes can be developed for lignocellulose biorefinery (LCB).LCBs can be harnessed with synthetic microbes to boost global bioeconomy.Yeasts can be engineered to enhance downstream process of LCB. Metabolic pathways of an organism depict its chemical repertoire and its genetic makeup. Autonomous synthetic microbes can be developed for lignocellulose biorefinery (LCB). LCBs can be harnessed with synthetic microbes to boost global bioeconomy. Yeasts can be engineered to enhance downstream process of LCB. |
| Druh dokumentu: | Article Other literature type |
| Popis souboru: | application/pdf |
| Jazyk: | English |
| ISSN: | 2165-5987 2165-5979 |
| DOI: | 10.1080/21655979.2023.2269328 |
| DOI: | 10.6084/m9.figshare.24347029.v1 |
| DOI: | 10.6084/m9.figshare.24347029 |
| Přístupová URL adresa: | https://pubmed.ncbi.nlm.nih.gov/37850721 https://ucrisportal.univie.ac.at/de/publications/a5ec4fb4-bf1e-4904-ad73-a6fdd106901f https://doi.org/10.1080/21655979.2023.2269328 https://hdl.handle.net/11353/10.2069159 https://phaidra.univie.ac.at/o:2069159 https://doi.org/10.1080/21655979.2023.2269328 |
| Rights: | CC BY NC CC BY URL: http://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/ (http://creativecommons.org/licenses/by-nc/4.0/) ), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent. |
| Přístupové číslo: | edsair.doi.dedup.....87c00facfa520c5786cb54ab54206500 |
| Databáze: | OpenAIRE |
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Nájsť tento článok vo Web of Science | Abstrakt: | The next milestone of synthetic biology research relies on the development of customized microbes for specific industrial purposes. Metabolic pathways of an organism, for example, depict its chemical repertoire and its genetic makeup. If genes controlling such pathways can be identified, scientists can decide to enhance or rewrite them for different purposes depending on the organism and the desired metabolites. The lignocellulosic biorefinery has achieved good progress over the past few years with potential impact on global bioeconomy. This principle aims to produce different bio-based products like biochemical(s) or biofuel(s) from plant biomass under microbial actions. Meanwhile, yeasts have proven very useful for different biotechnological applications. Hence, their potentials in genetic/metabolic engineering can be fully explored for lignocellulosic biorefineries. For instance, the secretion of enzymes above the natural limit (aided by genetic engineering) would speed-up the down-line processes in lignocellulosic biorefineries and the cost. Thus, the next milestone would greatly require the development of synthetic yeasts with much more efficient metabolic capacities to achieve basic requirements for particular biorefinery. This review gave comprehensive overview of lignocellulosic biomaterials and their importance in bioeconomy. Many researchers have demonstrated the engineering of several ligninolytic enzymes in heterologous yeast hosts. However, there are still many factors needing to be well understood like the secretion time, titter value, thermal stability, pH tolerance, and reactivity of the recombinant enzymes. Here, we give a detailed account of the potentials of engineered yeasts being discussed, as well as the constraints associated with their development and applications. Metabolic pathways of an organism depict its chemical repertoire and its genetic makeup.Autonomous synthetic microbes can be developed for lignocellulose biorefinery (LCB).LCBs can be harnessed with synthetic microbes to boost global bioeconomy.Yeasts can be engineered to enhance downstream process of LCB. Metabolic pathways of an organism depict its chemical repertoire and its genetic makeup. Autonomous synthetic microbes can be developed for lignocellulose biorefinery (LCB). LCBs can be harnessed with synthetic microbes to boost global bioeconomy. Yeasts can be engineered to enhance downstream process of LCB. |
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| ISSN: | 21655987 21655979 |
| DOI: | 10.1080/21655979.2023.2269328 |