Probing Molecular-Scale Oxidative Generation of Quinone Methides and Their Transformation Using Tip-Enhanced Raman Spectroscopy
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| Název: | Probing Molecular-Scale Oxidative Generation of Quinone Methides and Their Transformation Using Tip-Enhanced Raman Spectroscopy |
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| Autoři: | Keng-Jia Hsu, Chang-Lin Hsieh, Chi-Jui Tsai, Kien Voon Kong |
| Zdroj: | The Journal of Physical Chemistry Letters. 12:1110-1115 |
| Informace o vydavateli: | American Chemical Society (ACS), 2021. |
| Rok vydání: | 2021 |
| Témata: | Tip-Enhanced Raman Spectroscopy Qui, TERS, tip-enhanced Raman spectroscopy, Chemical Sciences not elsewhere classified, vibrational features, 02 engineering and technology, Spectrum Analysis, Raman, transition metal, DFT, 01 natural sciences, transition metal complexes, Space Science, Environmental Sciences not elsewhere classified, oxidative addition reaction, Cell Line, Tumor, Humans, metal oxidant-mediated transformation, Indolequinones, Density Functional Theory, Cancer, Evolutionary Biology, Ecology, chemical detection tool, Quinone Methides, oxidative generation, Molecular-Scale Oxidative Generation, 0104 chemical sciences, phenol species, Medicine, QM-mediated reactions, 0210 nano-technology, QM species, Oxidation-Reduction, metal oxidants, Biological Sciences not elsewhere classified |
| Popis: | Quinone methides (QMs) are very important intermediates in chemistry. These species are most often generated in situ with metal oxidants and transition metal complexes. Here, tip-enhanced Raman spectroscopy (TERS) has been implemented to investigate the in situ oxidative generation of a QM species from alkylphenols facilitated by a transition metal complex. Using TERS, the metal oxidant-mediated transformation of a phenol species has been observed. The subsequent oxidative addition reaction of QM has also been identified based on distinct vibrational features, which have been assigned based on density functional theory (DFT). This study may establish TERS as a chemical detection tool for various QM-mediated reactions. |
| Druh dokumentu: | Article |
| Jazyk: | English |
| ISSN: | 1948-7185 |
| DOI: | 10.1021/acs.jpclett.0c03313 |
| DOI: | 10.1021/acs.jpclett.0c03313.s001 |
| Přístupová URL adresa: | https://pubmed.ncbi.nlm.nih.gov/33475376 https://pubs.acs.org/doi/abs/10.1021/acs.jpclett.0c03313 https://pubmed.ncbi.nlm.nih.gov/33475376/ https://www.ncbi.nlm.nih.gov/pubmed/33475376 https://pubs.acs.org/doi/10.1021/acs.jpclett.0c03313 |
| Rights: | STM Policy #29 CC BY NC |
| Přístupové číslo: | edsair.doi.dedup.....83d075e98189001bca6923d1effa9cc9 |
| Databáze: | OpenAIRE |
Nájsť tento článok vo Web of Science | Abstrakt: | Quinone methides (QMs) are very important intermediates in chemistry. These species are most often generated in situ with metal oxidants and transition metal complexes. Here, tip-enhanced Raman spectroscopy (TERS) has been implemented to investigate the in situ oxidative generation of a QM species from alkylphenols facilitated by a transition metal complex. Using TERS, the metal oxidant-mediated transformation of a phenol species has been observed. The subsequent oxidative addition reaction of QM has also been identified based on distinct vibrational features, which have been assigned based on density functional theory (DFT). This study may establish TERS as a chemical detection tool for various QM-mediated reactions. |
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| ISSN: | 19487185 |
| DOI: | 10.1021/acs.jpclett.0c03313 |