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Outcomes of mechanical thrombectomy in acute stroke patients with atrial fibrillation detected after stroke versus known atrial fibrillation

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Title: Outcomes of mechanical thrombectomy in acute stroke patients with atrial fibrillation detected after stroke versus known atrial fibrillation
Authors: D'Anna, Lucio, Ornello, Raffaele, Foschi, Matteo, Romoli, Michele, Abu-Rumeileh, Samir, Dolkar, Tsering, Vittay, Orsolya, Dixon, Luke, Bentley, Paul, Brown, Zoe, Hall, Charles, Jamil, Sohaa, Jenkins, Harri, Kwan, Joseph, Patel, Maneesh, Rane, Neil, Roi, Dylan, Singh, Abhinav, Venter, Marius, Kalladka, Dheeraj, Malik, Abid, Halse, Omid, Sacco, Simona, Banerjee, Soma, Lobotesis, Kyriakos
Source: J Thromb Thrombolysis
Publisher Information: Springer Science and Business Media LLC, 2023.
Publication Year: 2023
Subject Terms: AFDAS, Atrail fibrillation, Mechanical thrombectomy, Atrial Fibrillation/complications [MeSH], Thrombectomy/methods [MeSH], Humans [MeSH], Prospective Studies [MeSH], Treatment Outcome [MeSH], Retrospective Studies [MeSH], Ischemic Stroke/complications [MeSH], Brain Ischemia/diagnosis [MeSH], Stroke/diagnosis [MeSH], Article, Thrombectomy/adverse effects [MeSH], Brain Ischemia, 3. Good health, Stroke, 03 medical and health sciences, Treatment Outcome, 0302 clinical medicine, Atrial Fibrillation, Humans, Prospective Studies, Ischemic Stroke, Thrombectomy, Retrospective Studies
Description: We aim to compare the outcomes in patients with atrial fibrillation detected after stroke (AFDAS) and their counterparts with known AF (KAF) presenting with large vessel occlusion (LVO) treated with mechanical thrombectomy (MT). This observational, prospective study included consecutive patients with acute LVO ischemic stroke of the anterior circulation with AFDAS, KAF and without AF. The primary study outcome was functional independence at 90 days after stroke. The secondary study outcomes were variation of the NIHSS score at 24 h, rate of successful reperfusion, death at 90 days and rate of immediate complications post-procedure. Overall, our cohort included 518 patients with acute ischemic stroke and LVO treated with MT, with 289 (56.8%) without a diagnosis of AF; 107 (21%) with AFDAS; 122 (22.2%) with KAF. There was no significant difference in terms of functional independence at 90 days after stroke between the three groups. Regarding the secondary study outcome, the rate of symptomatic intracranial haemorrhage (sICH) and/or parenchymal hematoma (PH) were significantly higher in the group of patients without AF (respectively, P = 0.030 and
Document Type: Article
Other literature type
Language: English
ISSN: 1573-742X
DOI: 10.1007/s11239-023-02923-6
Access URL: https://pubmed.ncbi.nlm.nih.gov/38127260
https://repository.publisso.de/resource/frl:6521885
https://hdl.handle.net/11697/222704
https://doi.org/10.1007/s11239-023-02923-6
Rights: CC BY
Accession Number: edsair.doi.dedup.....7ca546a9ed4d1cee187474066543e6d3
Database: OpenAIRE
Description
Abstract:We aim to compare the outcomes in patients with atrial fibrillation detected after stroke (AFDAS) and their counterparts with known AF (KAF) presenting with large vessel occlusion (LVO) treated with mechanical thrombectomy (MT). This observational, prospective study included consecutive patients with acute LVO ischemic stroke of the anterior circulation with AFDAS, KAF and without AF. The primary study outcome was functional independence at 90 days after stroke. The secondary study outcomes were variation of the NIHSS score at 24 h, rate of successful reperfusion, death at 90 days and rate of immediate complications post-procedure. Overall, our cohort included 518 patients with acute ischemic stroke and LVO treated with MT, with 289 (56.8%) without a diagnosis of AF; 107 (21%) with AFDAS; 122 (22.2%) with KAF. There was no significant difference in terms of functional independence at 90 days after stroke between the three groups. Regarding the secondary study outcome, the rate of symptomatic intracranial haemorrhage (sICH) and/or parenchymal hematoma (PH) were significantly higher in the group of patients without AF (respectively, P = 0.030 and
ISSN:1573742X
DOI:10.1007/s11239-023-02923-6