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CHEMICAL COMPOSITION AND BIOLOGICAL ACTIVITY OF METABOLITES OF MELILOTUS OFFICINALIS

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Bibliographic Details
Title: CHEMICAL COMPOSITION AND BIOLOGICAL ACTIVITY OF METABOLITES OF MELILOTUS OFFICINALIS
Authors: Erkin Khozhaykbarovich Botirov, Nargiza Kudiratullaevna Usmanova, Dildora Abdusmatovna Narbutaeva, Bakhtiyar Alimzhonovich Abdurakhmanov
Source: Chemistry of plant raw material; No 3 (2025); 23-42
Химия растительного сырья; № 3 (2025); 23-42
Publisher Information: Altai State University, 2025.
Publication Year: 2025
Subject Terms: coumarins, химический состав метаболитов, carotenoids, флавоноиды, biological activity, phenolic compounds, эфирное масло, Melilotus officinalis, биологическая активность, essential oil, кумарины, triterpenes, flavonoids, каротиноиды, тритерпены, chemical composition of metabolites, фенольные соединения
Description: The review summarizes the data from scientific literature on the chemical composition, level of study, and biological activity of metabolites and extracts of Melilotus officinalis (L.) Pall. (common sweet clover). In folk medicine, common sweet clover is used for angina, coronary thrombosis, thrombophlebitis, and for the prevention of heart attacks and ischemic strokes. The wide spectrum of pharmacological activity of M. officinalis is due to the content of a complex of biologically active substances. Analysis of literature data on the chemical composition of M. officinalis metabolites indicates its diversity. The article presents information on the composition of the metabolites of sweet clover, related to terpenoids, coumarins, hydroxybenzoic acids, derivatives of cinnamic and dihydrocinnamic acids, flavonoids and isoflavonoids, lipids, carbohydrates, carotenoids, triterpenoids, saponins, phytosterols, amino acids, vitamins, carboxylic acids and other classes of natural biologically active compounds. The results of the study of the pharmacological activity of the extraction preparations and some individual compounds of M. officinalis show the prospects for their further study in a number of areas, as well as their use for the creation of drugs and parapharmaceutical products on their basis. The goal and objective of this article is to summarize and systematize numerous literary data on secondary metabolites and biological activity of extracts and individual compounds isolated from M. officinalis. The information provided in the review can be used as reference literature by phytochemists, biologists and pharmacologists.e review can be used as reference literature by phytochemists, biologists and pharmacologists.
Document Type: Article
File Description: application/pdf
ISSN: 1029-5143
1029-5151
DOI: 10.14258/jcprm.20250315700
Access URL: https://journal.asu.ru/cw/article/view/15700
Rights: CC BY
Accession Number: edsair.doi.dedup.....727cc59b262744efb3f64ba0511329fc
Database: OpenAIRE
Description
Abstract:The review summarizes the data from scientific literature on the chemical composition, level of study, and biological activity of metabolites and extracts of Melilotus officinalis (L.) Pall. (common sweet clover). In folk medicine, common sweet clover is used for angina, coronary thrombosis, thrombophlebitis, and for the prevention of heart attacks and ischemic strokes. The wide spectrum of pharmacological activity of M. officinalis is due to the content of a complex of biologically active substances. Analysis of literature data on the chemical composition of M. officinalis metabolites indicates its diversity. The article presents information on the composition of the metabolites of sweet clover, related to terpenoids, coumarins, hydroxybenzoic acids, derivatives of cinnamic and dihydrocinnamic acids, flavonoids and isoflavonoids, lipids, carbohydrates, carotenoids, triterpenoids, saponins, phytosterols, amino acids, vitamins, carboxylic acids and other classes of natural biologically active compounds. The results of the study of the pharmacological activity of the extraction preparations and some individual compounds of M. officinalis show the prospects for their further study in a number of areas, as well as their use for the creation of drugs and parapharmaceutical products on their basis. The goal and objective of this article is to summarize and systematize numerous literary data on secondary metabolites and biological activity of extracts and individual compounds isolated from M. officinalis. The information provided in the review can be used as reference literature by phytochemists, biologists and pharmacologists.e review can be used as reference literature by phytochemists, biologists and pharmacologists.
ISSN:10295143
10295151
DOI:10.14258/jcprm.20250315700