Características clínicas y microbiológicas de la infección intra-abdominal complicada en Colombia: un estudio multicéntrico
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| Title: | Características clínicas y microbiológicas de la infección intra-abdominal complicada en Colombia: un estudio multicéntrico |
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| Authors: | Vallejo, Marta, Cuesta, Diana P, Flórez, Luz E, Correa, Adriana, Llanos, Carmen E, Isaza, Berenice, Vanegas, Stella, Osorio, Johanna, Casanova, Lucía, Villegas, María V |
| Source: | Revista chilena de infectología, Volume: 33, Issue: 3, Pages: 261-267, Published: JUN 2016 |
| Publisher Information: | SciELO Agencia Nacional de Investigacion y Desarrollo (ANID), 2016. |
| Publication Year: | 2016 |
| Subject Terms: | microbial, Adult, Male, 0301 basic medicine, abdominal infection, Microbial Sensitivity Tests, Colombia, Gram-Positive Bacteria, community-acquired infections, Statistics, Nonparametric, infección abdominal, Peritonitis/microbiology, 03 medical and health sciences, 0302 clinical medicine, Anti-Infective Agents, Reference Values, Risk Factors, Peritonitis/microbiología, fármaco-resistencia microbiana, Drug Resistance, Bacterial, Gram-Negative Bacteria, Humans, Aged, drug resistance, Middle Aged, 3. Good health, Community-Acquired Infections, Socioeconomic Factors, Intraabdominal Infections, Female, infecciones comunitarias |
| Description: | Complicated community-acquired intra-abdominal infections (CA-cIAI) are a common cause of acute abdomen.To identify the clinical and microbiology profile of CA-cIAI in four Colombian hospitals.This is a prospective, descriptive study, between 08-2012 and 09-2014, including patients with CA-cIAI > 15 years. Data collected included: socio-demographic, clinical, diagnosis, and isolates of the first culture obtained aseptically during surgery with antimicrobial susceptibility.192 patients were included, 62% men, median age 47.3 years. Co-morbidities were present in 38.4%, 13% had been hospitalized in the previous year 13%, and 9.4% had received antibiotics in the last 6 months; 44.3% were admitted for appendicitis, 17.7% for peritonitis and 16.7% for bowel perforation. CA-cIAI were assessed as moderate in 64.1% of the cases and were treated with ampicillin/sulbactam (SAM) and ertapenem. In 70.8% of cases a bacteria was isolated: 65.1% were gramnegative rods (80.0% Escherichia coli, 44.8% of them susceptible to pipercillin/tazobactam, 65.7% to SAM; 11.2 % were K.pneumoniae, 85% was susceptible for SAM; 16.7% were grampositive cocci (28.1% Streptococci viridans group). The median hospital stay was 7 days and 15.1% died.E. coli, K. pneumoniae and S. viridans were the main organisms to consider in an empiric therapy for CA-cIAI and it is important to know the local epidemiology in order to choose the right antibiotic. |
| Document Type: | Article |
| File Description: | text/html |
| Language: | English |
| ISSN: | 0716-1018 |
| DOI: | 10.4067/s0716-10182016000300002 |
| Access URL: | https://scielo.conicyt.cl/pdf/rci/v33n3/art02.pdf https://pubmed.ncbi.nlm.nih.gov/27598273 https://paperity.org/p/249677445/caracteristicas-clinicas-y-microbiologicas-de-la-infeccion-intra-abdominal-complicada-en http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-10182016000300002 https://pubmed.ncbi.nlm.nih.gov/27598273/ https://scielo.conicyt.cl/scielo.php?script=sci_arttext&pid=S0716-10182016000300002 https://scielo.conicyt.cl/pdf/rci/v33n3/art02.pdf https://www.ncbi.nlm.nih.gov/pubmed/27598273 http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-10182016000300002&lng=en&tlng=en |
| Rights: | CC BY NC |
| Accession Number: | edsair.doi.dedup.....6fb3647a2214743baf110842cf28d2c9 |
| Database: | OpenAIRE |
Nájsť tento článok vo Web of Science | Abstract: | Complicated community-acquired intra-abdominal infections (CA-cIAI) are a common cause of acute abdomen.To identify the clinical and microbiology profile of CA-cIAI in four Colombian hospitals.This is a prospective, descriptive study, between 08-2012 and 09-2014, including patients with CA-cIAI > 15 years. Data collected included: socio-demographic, clinical, diagnosis, and isolates of the first culture obtained aseptically during surgery with antimicrobial susceptibility.192 patients were included, 62% men, median age 47.3 years. Co-morbidities were present in 38.4%, 13% had been hospitalized in the previous year 13%, and 9.4% had received antibiotics in the last 6 months; 44.3% were admitted for appendicitis, 17.7% for peritonitis and 16.7% for bowel perforation. CA-cIAI were assessed as moderate in 64.1% of the cases and were treated with ampicillin/sulbactam (SAM) and ertapenem. In 70.8% of cases a bacteria was isolated: 65.1% were gramnegative rods (80.0% Escherichia coli, 44.8% of them susceptible to pipercillin/tazobactam, 65.7% to SAM; 11.2 % were K.pneumoniae, 85% was susceptible for SAM; 16.7% were grampositive cocci (28.1% Streptococci viridans group). The median hospital stay was 7 days and 15.1% died.E. coli, K. pneumoniae and S. viridans were the main organisms to consider in an empiric therapy for CA-cIAI and it is important to know the local epidemiology in order to choose the right antibiotic. |
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| ISSN: | 07161018 |
| DOI: | 10.4067/s0716-10182016000300002 |