Extensively drug-resistant Haemophilus influenzae isolated in Geneva, Switzerland
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| Název: | Extensively drug-resistant Haemophilus influenzae isolated in Geneva, Switzerland |
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| Autoři: | Cherkaoui, Abdessalam, Francois, Patrice, Gaia, Nadia, Renzi, Gesuele, Fischer, Adrien, Schrenzel, Jacques |
| Zdroj: | Eur J Clin Microbiol Infect Dis |
| Informace o vydavateli: | Springer Science and Business Media LLC, 2025. |
| Rok vydání: | 2025 |
| Témata: | Male, Ceftriaxone resistance, Haemophilus influenzae / genetics, Haemophilus Infections, Whole Genome Sequencing, Brief Report, Sputum, Haemophilus influenzae / classification, Extensively drug resistant, Microbial Sensitivity Tests, Middle Aged, Anti-Bacterial Agents / pharmacology, Haemophilus influenzae, Haemophilus influenzae / drug effects, Anti-Bacterial Agents, Haemophilus Infections / microbiology, Drug Resistance, Multiple, Bacterial, Sputum / microbiology, Humans, Haemophilus influenzae / isolation & purification, Penicillin-binding protein 3 amino acid substitutions, Switzerland |
| Popis: | The emergence of multi-drug resistant (MDR) and even extensively drug-resistant (XDR) strains among H. influenzae was observed in some Asian countries. Herein, we reported the first XDR H. influenzae isolated in Geneva, Switzerland. This strain was isolated in a good-quality sputum sample from a 63 year-old male patient. There was no respiratory infection diagnosed at that time. The strain was non-typeable and pan-β-lactam resistant. According to whole genome sequencing analysis it belongs to sequence type 159 and the ST-107 clonal complex. It was classified into group III + regarding the amino acid substitutions identified in the transpeptidase domain of PBP3. |
| Druh dokumentu: | Article Other literature type |
| Popis souboru: | application/pdf |
| Jazyk: | English |
| ISSN: | 1435-4373 0934-9723 |
| DOI: | 10.1007/s10096-025-05093-w |
| Přístupová URL adresa: | https://pubmed.ncbi.nlm.nih.gov/40048099 |
| Rights: | CC BY |
| Přístupové číslo: | edsair.doi.dedup.....6d1b41b2f76c58b406f8ff1dd6db33d3 |
| Databáze: | OpenAIRE |
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Nájsť tento článok vo Web of Science | Abstrakt: | The emergence of multi-drug resistant (MDR) and even extensively drug-resistant (XDR) strains among H. influenzae was observed in some Asian countries. Herein, we reported the first XDR H. influenzae isolated in Geneva, Switzerland. This strain was isolated in a good-quality sputum sample from a 63 year-old male patient. There was no respiratory infection diagnosed at that time. The strain was non-typeable and pan-β-lactam resistant. According to whole genome sequencing analysis it belongs to sequence type 159 and the ST-107 clonal complex. It was classified into group III + regarding the amino acid substitutions identified in the transpeptidase domain of PBP3. |
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| ISSN: | 14354373 09349723 |
| DOI: | 10.1007/s10096-025-05093-w |