Coronary angiography in patients with kidney dysfunction and myocardial injury: A retrospective cohort study on management of myocardial injury in hospitalized patients with kidney disease: A retrospective cohort study on management of myocardial injury in hospitalized patients with kidney disease
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| Názov: | Coronary angiography in patients with kidney dysfunction and myocardial injury: A retrospective cohort study on management of myocardial injury in hospitalized patients with kidney disease: A retrospective cohort study on management of myocardial injury in hospitalized patients with kidney disease |
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| Autori: | Illum, Emilie, Kofod, Dea Haagensen, Ballegaard, Ellen Freese, Nelveg-Kristensen, Karl Emil, Hornum, Mads, Schou, Morten, Torp-Pedersen, Christian, Gislason, Gunnar, Lassen, Jens Flensted, Carlson, Nicholas |
| Zdroj: | Illum, E, Kofod, D H, Ballegaard, E F, Nelveg-Kristensen, K E, Hornum, M, Schou, M, Torp-Pedersen, C, Gislason, G, Lassen, J F & Carlson, N 2024, ' Coronary angiography in patients with kidney dysfunction and myocardial injury : A retrospective cohort study on management of myocardial injury in hospitalized patients with kidney disease ', Cardiovascular Revascularization Medicine, vol. 63, pp. 59-65 . https://doi.org/10.1016/j.carrev.2024.01.001 |
| Informácie o vydavateľovi: | Elsevier BV, 2024. |
| Rok vydania: | 2024 |
| Predmety: | Male, Time Factors, Coronary angiography, Denmark, Coronary Angiography, Kidney, Risk Assessment, Troponin T, Risk Factors, Predictive Value of Tests, Chronic kidney disease, 80 and over, Humans, Renal Insufficiency/mortality, Registries, Renal Insufficiency, Troponin T/blood, Retrospective Studies, Aged, Aged, 80 and over, 2. Zero hunger, Kidney Diseases/diagnosis, Kidney insufficiency, Middle Aged, Denmark/epidemiology, 3. Good health, Hospitalization, Treatment Outcome, Myocardial injury, Myocardial Revascularization/adverse effects, Female, Biomarkers/blood, Kidney/physiopathology, Biomarkers, Glomerular Filtration Rate |
| Popis: | Although kidney insufficiency has been shown to be associated with increased risk of myocardial injury, benefit of coronary angiography (CAG) and revascularization remains uncertain, with implications on management strategies and outcomes. We aimed to compare rates of CAG and revascularization and subsequent risk of cardiovascular and kidney outcomes in hospitalized patients with myocardial injury and kidney dysfunction.Retrospective cohort study encompassing hospitalized patients with myocardial injury i.e. elevated troponin I or T and an eGFR ≤60 ml/min/1.73 m2 identified between 2011 and 2021 in Danish national registers. 30-day odds for CAG were computed across granular eGFR-categories based on multiple logistic regression. Standardized one-year risks of cardiovascular and kidney outcomes including mortality were determined based on hazards obtained in multiple Cox regression.A total of 52,798 patients with myocardial injury were identified. CAG was performed in 14.3 % (n = 7549). 30-day odds ratios for CAG were 0.64 [0.60-0.68], 0.38 [0.34-0.42], 0.18 [0.14-0.22], and 0.35 [0.30-0.40] in patients with eGFR 31-45 ml/min/1.73 m2, eGFR 15-30 ml/min/1.73 m2 for eGFR |
| Druh dokumentu: | Article |
| Popis súboru: | application/pdf |
| Jazyk: | English |
| ISSN: | 1553-8389 |
| DOI: | 10.1016/j.carrev.2024.01.001 |
| Prístupová URL adresa: | https://pubmed.ncbi.nlm.nih.gov/38212237 https://curis.ku.dk/ws/files/398959967/1_s2.0_S1553838924000022_main_1_.pdf |
| Rights: | CC BY NC |
| Prístupové číslo: | edsair.doi.dedup.....65420782331a6cdfcce2c11683a66758 |
| Databáza: | OpenAIRE |
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Nájsť tento článok vo Web of Science | Abstrakt: | Although kidney insufficiency has been shown to be associated with increased risk of myocardial injury, benefit of coronary angiography (CAG) and revascularization remains uncertain, with implications on management strategies and outcomes. We aimed to compare rates of CAG and revascularization and subsequent risk of cardiovascular and kidney outcomes in hospitalized patients with myocardial injury and kidney dysfunction.Retrospective cohort study encompassing hospitalized patients with myocardial injury i.e. elevated troponin I or T and an eGFR ≤60 ml/min/1.73 m2 identified between 2011 and 2021 in Danish national registers. 30-day odds for CAG were computed across granular eGFR-categories based on multiple logistic regression. Standardized one-year risks of cardiovascular and kidney outcomes including mortality were determined based on hazards obtained in multiple Cox regression.A total of 52,798 patients with myocardial injury were identified. CAG was performed in 14.3 % (n = 7549). 30-day odds ratios for CAG were 0.64 [0.60-0.68], 0.38 [0.34-0.42], 0.18 [0.14-0.22], and 0.35 [0.30-0.40] in patients with eGFR 31-45 ml/min/1.73 m2, eGFR 15-30 ml/min/1.73 m2 for eGFR |
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| ISSN: | 15538389 |
| DOI: | 10.1016/j.carrev.2024.01.001 |