Risk of Carotid Atherosclerosis in Subjects with Prediabetes Overlapping Metabolic Syndrome
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| Title: | Risk of Carotid Atherosclerosis in Subjects with Prediabetes Overlapping Metabolic Syndrome |
|---|---|
| Authors: | Seol A Jang, Kyoung Min Kim, Seok Won Park, Chul Sik Kim |
| Contributors: | Seol A Jang, Kyoung Min Kim, Seok Won Park, Chul Sik Kim, Kim, Kyung Min |
| Source: | Metabolic Syndrome and Related Disorders. 20:599-605 |
| Publisher Information: | Mary Ann Liebert Inc, 2022. |
| Publication Year: | 2022 |
| Subject Terms: | Metabolic Syndrome, Carotid Artery Diseases, carotid plaque, Metabolic Syndrome* / complications, carotid atherosclerosis, Carotid Artery Diseases* / epidemiology, Carotid Artery Diseases* / complications, Carotid Artery Diseases* / diagnostic imaging, prediabetes, Metabolic Syndrome* / epidemiology, Carotid Intima-Media Thickness, metabolic syndrome, Prediabetic State, 03 medical and health sciences, Prediabetic State* / complications, 0302 clinical medicine, Risk Factors, Humans, Prediabetic State* / epidemiology |
| Description: | Background: While the number of individuals with prediabetes and metabolic syndrome (MetS) is increasing, only a few studies have reported differences in cardiovascular risk according to the presence or absence of MetS in individuals with prediabetes. Here, we examined differences in carotid intima-media thickness (CIMT) and carotid plaques in individuals with prediabetes with or without MetS among subjects who visited a single center in Seoul (Huh Diabetes Center). Methods: A total of 328 participants aged ≥20 years, including the group with normoglycemia, were enrolled in the analysis, of which 273 had prediabetes. Individuals with prediabetes were defined as those who met one or more of the following two criteria: fasting plasma glucose of 100-125 mg/dL and/or HbA1c level of 5.7%-6.4%. Carotid atherosclerosis was determined by mean and maximal CIMT and by the presence of carotid plaques. Results: Eighty-nine subjects (32.6% of prediabetes group) were categorized as having MetS. Those with MetS had significantly higher mean CIMT and maximal CIMT than those without (P |
| Document Type: | Article |
| Language: | English |
| ISSN: | 1557-8518 1540-4196 |
| DOI: | 10.1089/met.2022.0040 |
| Access URL: | https://pubmed.ncbi.nlm.nih.gov/36251877 |
| Rights: | Mary Ann Liebert TDM CC BY NC ND |
| Accession Number: | edsair.doi.dedup.....61e69274f738580d196da520d0749173 |
| Database: | OpenAIRE |
| Abstract: | Background: While the number of individuals with prediabetes and metabolic syndrome (MetS) is increasing, only a few studies have reported differences in cardiovascular risk according to the presence or absence of MetS in individuals with prediabetes. Here, we examined differences in carotid intima-media thickness (CIMT) and carotid plaques in individuals with prediabetes with or without MetS among subjects who visited a single center in Seoul (Huh Diabetes Center). Methods: A total of 328 participants aged ≥20 years, including the group with normoglycemia, were enrolled in the analysis, of which 273 had prediabetes. Individuals with prediabetes were defined as those who met one or more of the following two criteria: fasting plasma glucose of 100-125 mg/dL and/or HbA1c level of 5.7%-6.4%. Carotid atherosclerosis was determined by mean and maximal CIMT and by the presence of carotid plaques. Results: Eighty-nine subjects (32.6% of prediabetes group) were categorized as having MetS. Those with MetS had significantly higher mean CIMT and maximal CIMT than those without (P |
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| ISSN: | 15578518 15404196 |
| DOI: | 10.1089/met.2022.0040 |
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