Risk of Carotid Atherosclerosis in Subjects with Prediabetes Overlapping Metabolic Syndrome

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Bibliographic Details
Title: Risk of Carotid Atherosclerosis in Subjects with Prediabetes Overlapping Metabolic Syndrome
Authors: Seol A Jang, Kyoung Min Kim, Seok Won Park, Chul Sik Kim
Contributors: Seol A Jang, Kyoung Min Kim, Seok Won Park, Chul Sik Kim, Kim, Kyung Min
Source: Metabolic Syndrome and Related Disorders. 20:599-605
Publisher Information: Mary Ann Liebert Inc, 2022.
Publication Year: 2022
Subject Terms: Metabolic Syndrome, Carotid Artery Diseases, carotid plaque, Metabolic Syndrome* / complications, carotid atherosclerosis, Carotid Artery Diseases* / epidemiology, Carotid Artery Diseases* / complications, Carotid Artery Diseases* / diagnostic imaging, prediabetes, Metabolic Syndrome* / epidemiology, Carotid Intima-Media Thickness, metabolic syndrome, Prediabetic State, 03 medical and health sciences, Prediabetic State* / complications, 0302 clinical medicine, Risk Factors, Humans, Prediabetic State* / epidemiology
Description: Background: While the number of individuals with prediabetes and metabolic syndrome (MetS) is increasing, only a few studies have reported differences in cardiovascular risk according to the presence or absence of MetS in individuals with prediabetes. Here, we examined differences in carotid intima-media thickness (CIMT) and carotid plaques in individuals with prediabetes with or without MetS among subjects who visited a single center in Seoul (Huh Diabetes Center). Methods: A total of 328 participants aged ≥20 years, including the group with normoglycemia, were enrolled in the analysis, of which 273 had prediabetes. Individuals with prediabetes were defined as those who met one or more of the following two criteria: fasting plasma glucose of 100-125 mg/dL and/or HbA1c level of 5.7%-6.4%. Carotid atherosclerosis was determined by mean and maximal CIMT and by the presence of carotid plaques. Results: Eighty-nine subjects (32.6% of prediabetes group) were categorized as having MetS. Those with MetS had significantly higher mean CIMT and maximal CIMT than those without (P
Document Type: Article
Language: English
ISSN: 1557-8518
1540-4196
DOI: 10.1089/met.2022.0040
Access URL: https://pubmed.ncbi.nlm.nih.gov/36251877
Rights: Mary Ann Liebert TDM
CC BY NC ND
Accession Number: edsair.doi.dedup.....61e69274f738580d196da520d0749173
Database: OpenAIRE
Description
Abstract:Background: While the number of individuals with prediabetes and metabolic syndrome (MetS) is increasing, only a few studies have reported differences in cardiovascular risk according to the presence or absence of MetS in individuals with prediabetes. Here, we examined differences in carotid intima-media thickness (CIMT) and carotid plaques in individuals with prediabetes with or without MetS among subjects who visited a single center in Seoul (Huh Diabetes Center). Methods: A total of 328 participants aged ≥20 years, including the group with normoglycemia, were enrolled in the analysis, of which 273 had prediabetes. Individuals with prediabetes were defined as those who met one or more of the following two criteria: fasting plasma glucose of 100-125 mg/dL and/or HbA1c level of 5.7%-6.4%. Carotid atherosclerosis was determined by mean and maximal CIMT and by the presence of carotid plaques. Results: Eighty-nine subjects (32.6% of prediabetes group) were categorized as having MetS. Those with MetS had significantly higher mean CIMT and maximal CIMT than those without (P
ISSN:15578518
15404196
DOI:10.1089/met.2022.0040