Assessing inhibitory control deficits in adult ADHD: A systematic review and meta-analysis of the stop-signal task
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| Názov: | Assessing inhibitory control deficits in adult ADHD: A systematic review and meta-analysis of the stop-signal task |
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| Autori: | Daniel Senkowski, Theresa Ziegler, Mervyn Singh, Andreas Heinz, Jason He, Tim Silk, Robert C. Lorenz |
| Zdroj: | Neuropsychol Rev Neuropsychology Review |
| Informácie o vydavateľovi: | Cold Spring Harbor Laboratory, 2022. |
| Rok vydania: | 2022 |
| Predmety: | cognition, Adult, cognitive deficits, neuropsychology, impulsivity, Review, Neuropsychological Tests, Attention Deficit Disorder with Hyperactivity/psychology [MeSH], Adult [MeSH], Humans [MeSH], Attention deficit hyperactivity disorder, Executive Function/physiology [MeSH], Inhibition, Psychological [MeSH], Attention, Attention Deficit Disorder with Hyperactivity/physiopathology [MeSH], Neuropsychology, Reaction Time/physiology [MeSH], Impulsivity, Cognitive deficits, Cognition, Neuropsychological Tests [MeSH], attention, 3. Good health, Inhibition, Psychological, Executive Function, 03 medical and health sciences, attention deficit hyperactivity disorder, 0302 clinical medicine, Attention Deficit Disorder with Hyperactivity, Reaction Time, Humans |
| Popis: | BackgroundIn recent years, there has been an increasing quest in improving our understanding of neurocognitive deficits underlying adult attention-deficit/hyperactivity disorder (ADHD). Current statistical manuals of psychiatric disorders emphasize inattention and hyperactivity-impulsivity symptoms, but empirical studies have also shown consistent alterations in inhibitory control. Thus far, there is no established neuropsychological test to assess inhibitory control deficits in adult ADHD. A common paradigm for assessing response inhibition is the stop-signal task (SST).MethodsFollowing PRISMA-selection criteria, our systematic review and meta-analysis integrated the findings of 26 publications with 27 studies examining the SST in adult ADHD.ResultsThe meta-analysis, which included 883 patients with adult ADHD and 916 control participants, revealed reliable inhibitory control deficits, as expressed in prolonged SST response times, with a moderate effect size g = 0.51. The deficits were not moderated by study quality, sample characteristics or clinical parameters, suggesting that they may be a phenotype in this disorder. The analyses of secondary outcome measures revealed greater SST omission errors and reduced go accuracy in patients, indicative of altered sustained attention. However, only few (NDiscussionOur meta-analysis suggests that the SST could, in conjunction with other tests and questionnaires, become a valuable tool for the assessment of inhibitory control deficits in adult ADHD. |
| Druh dokumentu: | Article Other literature type |
| Popis súboru: | application/pdf |
| ISSN: | 1573-6660 1040-7308 |
| DOI: | 10.1101/2022.07.09.22277429 |
| DOI: | 10.1007/s11065-023-09592-5 |
| DOI: | 10.17169/refubium-49527 |
| Prístupová URL adresa: | https://pubmed.ncbi.nlm.nih.gov/37300725 http://hdl.handle.net/21.11116/0000-000F-7AC7-8 http://hdl.handle.net/21.11116/0000-000F-7AC8-7 http://hdl.handle.net/21.11116/0000-000A-B5B4-E http://hdl.handle.net/21.11116/0000-000A-B5B5-D http://hdl.handle.net/21.11116/0000-000A-B5B2-0 https://repository.publisso.de/resource/frl:6521523 |
| Rights: | CC BY URL: http://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (http://creativecommons.org/licenses/by/4.0/) . |
| Prístupové číslo: | edsair.doi.dedup.....5f62616cc43b6dea2685e68df53b2283 |
| Databáza: | OpenAIRE |
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Nájsť tento článok vo Web of Science | Abstrakt: | BackgroundIn recent years, there has been an increasing quest in improving our understanding of neurocognitive deficits underlying adult attention-deficit/hyperactivity disorder (ADHD). Current statistical manuals of psychiatric disorders emphasize inattention and hyperactivity-impulsivity symptoms, but empirical studies have also shown consistent alterations in inhibitory control. Thus far, there is no established neuropsychological test to assess inhibitory control deficits in adult ADHD. A common paradigm for assessing response inhibition is the stop-signal task (SST).MethodsFollowing PRISMA-selection criteria, our systematic review and meta-analysis integrated the findings of 26 publications with 27 studies examining the SST in adult ADHD.ResultsThe meta-analysis, which included 883 patients with adult ADHD and 916 control participants, revealed reliable inhibitory control deficits, as expressed in prolonged SST response times, with a moderate effect size g = 0.51. The deficits were not moderated by study quality, sample characteristics or clinical parameters, suggesting that they may be a phenotype in this disorder. The analyses of secondary outcome measures revealed greater SST omission errors and reduced go accuracy in patients, indicative of altered sustained attention. However, only few (NDiscussionOur meta-analysis suggests that the SST could, in conjunction with other tests and questionnaires, become a valuable tool for the assessment of inhibitory control deficits in adult ADHD. |
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| ISSN: | 15736660 10407308 |
| DOI: | 10.1101/2022.07.09.22277429 |