Precancerous lesions of the stomach, gastric cancer and hereditary gastric cancer syndromes
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| Název: | Precancerous lesions of the stomach, gastric cancer and hereditary gastric cancer syndromes |
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| Autoři: | Gullo, Irene, Grillo, Federica, Mastracci, Luca, Vanoli, Alessandro, Carneiro, Fatima, Saragoni, Luca, Limarzi, Francesco, Ferro, Jacopo, Parente, Paola, Fassan, Matteo |
| Přispěvatelé: | Instituto de Investigação e Inovação em Saúde, Gullo, I., Grillo, F., Mastracci, L., Vanoli, A., Carneiro, F., Saragoni, L., Limarzi, F., Ferro, J., Parente, P., Fassan, M. |
| Zdroj: | Pathologica |
| Informace o vydavateli: | Siapec Servizi Srl, 2020. |
| Rok vydání: | 2020 |
| Témata: | gastric adenocarcinoma, gastric cancer, gastric dysplasia, hereditary diffuse gastric cancer (HDGC), hereditary gastric cancer syndromes, Gastric dysplasia, Stomach Neoplasms / diagnosis, Review, Hereditary gastric cancer syndromes, Adenocarcinoma, Neoplastic Syndromes, Hereditary / genetics, 03 medical and health sciences, 0302 clinical medicine, Neoplastic Syndromes, Hereditary, Stomach Neoplasms, Hereditary diffuse gastric cancer (HDGC), Neoplastic Syndromes, Hereditary / pathology, Stomach Neoplasms / epidemiology, Humans, Genetic Predisposition to Disease, Stomach Neoplasms / genetics, Gastric adenocarcinoma, Neoplastic Syndromes, Hereditary / epidemiology, Incidence, Stomach, Prognosis, 3. Good health, Neoplastic Syndromes, Hereditary / diagnosis, Stomach / pathology, Gastric cancer, Stomach Neoplasms / pathology, Precancerous Conditions |
| Popis: | Gastric cancer accounts for about 6% of cancers worldwide, being the fifth most frequently diagnosed malignancy and the third leading cause of cancer related death. Gastric carcinogenesis is a multistep and multifactorial process and is the result of the complex interplay between genetic susceptibility and environmental factors. The identification of predisposing conditions and of precancerous lesions is the basis for screening programs and early stage treatment. Furthermore, although most gastric cancers are sporadic, familial clustering is observed in up to 10% of patients. Among them, hereditary cases, related to known cancer susceptibility syndromes and/or genetic causes are thought to account for 1-3% of all gastric cancers. The pathology report of gastric resections specimens therefore requires a standardized approach as well as in depth knowledge of prognostic and treatment associated factors. |
| Druh dokumentu: | Article Other literature type |
| Popis souboru: | application/pdf |
| ISSN: | 1591-951X |
| DOI: | 10.32074/1591-951x-166 |
| Přístupová URL adresa: | https://www.pathologica.it/article/download/166/169 https://pubmed.ncbi.nlm.nih.gov/33179620 https://www.pathologica.it/article/download/166/169 https://pubmed.ncbi.nlm.nih.gov/33179620/ https://www.pathologica.it/article/view/166 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7931572 https://europepmc.org/article/MED/33179620 https://moh-it.pure.elsevier.com/en/publications/precancerous-lesions-of-the-stomach-gastric-cancer-and-hereditary https://hdl.handle.net/10216/145232 |
| Rights: | CC BY NC ND URL: http://creativecommons.org/licenses/by-nc-nd/4.0/deed.en |
| Přístupové číslo: | edsair.doi.dedup.....5bcc1a544474a402b14b576c33479024 |
| Databáze: | OpenAIRE |
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Nájsť tento článok vo Web of Science | Abstrakt: | Gastric cancer accounts for about 6% of cancers worldwide, being the fifth most frequently diagnosed malignancy and the third leading cause of cancer related death. Gastric carcinogenesis is a multistep and multifactorial process and is the result of the complex interplay between genetic susceptibility and environmental factors. The identification of predisposing conditions and of precancerous lesions is the basis for screening programs and early stage treatment. Furthermore, although most gastric cancers are sporadic, familial clustering is observed in up to 10% of patients. Among them, hereditary cases, related to known cancer susceptibility syndromes and/or genetic causes are thought to account for 1-3% of all gastric cancers. The pathology report of gastric resections specimens therefore requires a standardized approach as well as in depth knowledge of prognostic and treatment associated factors. |
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| ISSN: | 1591951X |
| DOI: | 10.32074/1591-951x-166 |