Zobraziť v EDS

Delayed facial nerve palsy after vestibular schwannoma resection: risk factors, extent and prognosis

Uložené v:
Podrobná bibliografia
Názov: Delayed facial nerve palsy after vestibular schwannoma resection: risk factors, extent and prognosis
Autori: Miriam Simon, Laurenz Althaus, Manuel Burggraf, Angelika Albrecht, Jörg Schipper, Julia Kristin
Zdroj: Eur Arch Otorhinolaryngol
Informácie o vydavateľovi: Springer Science and Business Media LLC, 2024.
Rok vydania: 2024
Predmety: Male, Adult, Microsurgery, Time Factors, Facial Paralysis, Medizin, Otology, Neuroma, Acoustic, Middle Aged, Prognosis, Facial Paralysis/epidemiology [MeSH], Female [MeSH], Vestibular schwannoma, Aged [MeSH], Adult [MeSH], Humans [MeSH], Neuroma, Acoustic/surgery [MeSH], Postoperative Complications/epidemiology [MeSH], Retrospective Studies [MeSH], Middle Aged [MeSH], Risk Factors [MeSH], Time Factors [MeSH], Microsurgery/methods [MeSH], Cranial nerve failure, Delayed facial nerve palsy, Male [MeSH], Microsurgery/adverse effects [MeSH], Facial Paralysis/etiology [MeSH], Skull base surgery, Prognosis [MeSH], Postoperative Complications/etiology [MeSH], Facial nerve outcomes, 03 medical and health sciences, Postoperative Complications, 0302 clinical medicine, Risk Factors, Humans, Female, Retrospective Studies, Aged
Popis: Introduction Facial nerve palsies may develop during the postoperative period of microsurgical removal of vestibular schwannomas (VSs), even after normal facial function for days or weeks after surgery. The aim of this study was to identify the pathomechanism and predictive factors of delayed palsy. Material and method The clinical data of 193 patients who underwent vestibular schwannoma surgery between 2012 and 2021 were retrospectively analyzed. A total of 134 patients were included. The patients showed intact facial nerve function up to 24 h after surgery. All patients (n = 20) with palsy from postoperative day 4 were included and collectively referred to as delayed facial nerve palsy (DFNP). Various factors were checked using a binomial regression analysis. Results The mean age of patients with DFNP was 57.8 years (55% female, 45% male). 70% had VS with KOOS ≥ 3, and 60% underwent surgery via a translabyrinthine approach Among the 16 patients with DFNP-related neurotropic pathogens, 25% were seropositive for herpes simplex virus. Most patients (n = 9/20) experienced onset of palsy between postoperative days 6 and 10. Of the four variables included in the significance test, three were significant: KOOS ≥ 3 (p p p Summary The parameters mentioned above (KOOS classification and ipsilateral vestibular dysfunction) could be proven risk factors for the occurrence of DFNP.
Druh dokumentu: Article
Other literature type
Popis súboru: Text
Jazyk: English
ISSN: 1434-4726
0937-4477
DOI: 10.1007/s00405-024-08883-8
Prístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/39127799
https://repository.publisso.de/resource/frl:6497035
https://www.ncbi.nlm.nih.gov/pubmed/39127799
https://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&origin=inward&scp=85200949858
https://doi.org/10.1007/s00405-024-08883-8
Rights: CC BY
Prístupové číslo: edsair.doi.dedup.....51aff08fd724e1519df58b7121bd1ea7
Databáza: OpenAIRE
Popis
Abstrakt:Introduction Facial nerve palsies may develop during the postoperative period of microsurgical removal of vestibular schwannomas (VSs), even after normal facial function for days or weeks after surgery. The aim of this study was to identify the pathomechanism and predictive factors of delayed palsy. Material and method The clinical data of 193 patients who underwent vestibular schwannoma surgery between 2012 and 2021 were retrospectively analyzed. A total of 134 patients were included. The patients showed intact facial nerve function up to 24 h after surgery. All patients (n = 20) with palsy from postoperative day 4 were included and collectively referred to as delayed facial nerve palsy (DFNP). Various factors were checked using a binomial regression analysis. Results The mean age of patients with DFNP was 57.8 years (55% female, 45% male). 70% had VS with KOOS ≥ 3, and 60% underwent surgery via a translabyrinthine approach Among the 16 patients with DFNP-related neurotropic pathogens, 25% were seropositive for herpes simplex virus. Most patients (n = 9/20) experienced onset of palsy between postoperative days 6 and 10. Of the four variables included in the significance test, three were significant: KOOS ≥ 3 (p p p Summary The parameters mentioned above (KOOS classification and ipsilateral vestibular dysfunction) could be proven risk factors for the occurrence of DFNP.
ISSN:14344726
09374477
DOI:10.1007/s00405-024-08883-8