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Viral load of SARS-CoV-2 across patients and compared to other respiratory viruses

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Title: Viral load of SARS-CoV-2 across patients and compared to other respiratory viruses
Authors: Jacot, Damien, Greub, Gilbert, Jaton, Katia, Opota, Onya
Source: Microbes Infect
Microbes and infection, vol. 22, no. 10, pp. 617-621
Microbes and Infection
Publisher Information: Cold Spring Harbor Laboratory, 2020.
Publication Year: 2020
Subject Terms: Adult, Male, 0301 basic medicine, Adolescent, Short Communication, Immunology, Respiratory Syncytial Virus Infections, Microbiology, 03 medical and health sciences, Influenza, Human, Humans, Child, Pandemics, Aged, Aged, 80 and over, 0303 health sciences, Infant, Newborn, COVID-19, Infant, Middle Aged, 3. Good health, Influenza B virus, Infectious Diseases, COVID-19 Nucleic Acid Testing, Child, Preschool, COVID-19/diagnosis, COVID-19/virology, Coronavirus Infections/diagnosis, Coronavirus Infections/virology, Disease Progression, Female, Influenza B virus/isolation & purification, Influenza, Human/virology, Respiratory Syncytial Virus Infections/virology, Respiratory Syncytial Viruses/isolation & purification, SARS-CoV-2/isolation & purification, Serologic Tests/methods, Switzerland/epidemiology, Viral Load/statistics & numerical data, Cycle threshold, Diagnostic, RT-PCR, SARS-CoV-2, Viral load, Coronavirus Infections
Description: RT-PCRs to detect SARS-CoV-2 RNA is key to manage the COVID-19 pandemic. We analyzed SARS-CoV-2 viral loads from 22’323 RT-PCR results according to samples types, gender, age, and health units. Viral load did not show any difference across age and appears to be a poor predictor of disease outcome. SARS-CoV-2 viral load showed similar high viral loads than the one observed for RSV and influenza B. The importance of viral load to predict contagiousness and to assess disease progression is discussed.
Document Type: Article
Other literature type
File Description: application/pdf
ISSN: 1286-4579
DOI: 10.1101/2020.07.15.20154518
DOI: 10.1016/j.micinf.2020.08.004
Access URL: https://pubmed.ncbi.nlm.nih.gov/32911086
https://www.medrxiv.org/content/10.1101/2020.07.15.20154518v1.article-info
https://www.medrxiv.org/content/medrxiv/early/2020/09/03/2020.07.15.20154518.full.pdf
http://www.medrxiv.org/content/10.1101/2020.07.15.20154518v1
https://www.medrxiv.org/content/10.1101/2020.07.15.20154518v1
https://pubmed.ncbi.nlm.nih.gov/32911086/
https://www.sciencedirect.com/science/article/pii/S1286457920301519
https://www.ncbi.nlm.nih.gov/pubmed/32911086
https://search.bvsalud.org/global-literature-on-novel-coronavirus-2019-ncov/resource/en/ppmedrxiv-20154518
https://serval.unil.ch/notice/serval:BIB_E9FEEDB7A5B4
https://serval.unil.ch/notice/serval:BIB_E9FEEDB7A5B4
https://serval.unil.ch/resource/serval:BIB_E9FEEDB7A5B4.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_E9FEEDB7A5B40
Rights: Elsevier Non-Commercial
Elsevier TDM
Accession Number: edsair.doi.dedup.....4f59feaff097d716f0fa89c730eae369
Database: OpenAIRE
Description
Abstract:RT-PCRs to detect SARS-CoV-2 RNA is key to manage the COVID-19 pandemic. We analyzed SARS-CoV-2 viral loads from 22’323 RT-PCR results according to samples types, gender, age, and health units. Viral load did not show any difference across age and appears to be a poor predictor of disease outcome. SARS-CoV-2 viral load showed similar high viral loads than the one observed for RSV and influenza B. The importance of viral load to predict contagiousness and to assess disease progression is discussed.
ISSN:12864579
DOI:10.1101/2020.07.15.20154518