Effect of Home Blood Pressure Monitoring on Patient’s Awareness and Goal Attainment Under Antihypertensive Therapy: The Factors Influencing Results in Anti-HypertenSive Treatment (FIRST) Study

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Názov: Effect of Home Blood Pressure Monitoring on Patient’s Awareness and Goal Attainment Under Antihypertensive Therapy: The Factors Influencing Results in Anti-HypertenSive Treatment (FIRST) Study
Autori: Spirk, David, Noll, Sarah, Burnier, Michel, Rimoldi, Stefano, Noll, Georg, Sudano, Isabella
Prispievatelia: University of Zurich, Sudano, Isabella
Zdroj: Kidney & Blood Pressure Research, Vol 43, Iss 3, Pp 979-986 (2018)
Kidney & blood pressure research, vol. 43, no. 3, pp. 979-986
Spirk, David; Noll, Sarah; Burnier, Michel; Rimoldi, Stefano; Noll, Georg; Sudano, Isabella (2018). Effect of Home Blood Pressure Monitoring on Patient's Awareness and Goal Attainment Under Antihypertensive Therapy: The Factors Influencing Results in Anti-HypertenSive Treatment (FIRST) Study. Kidney & blood pressure research, 43(3), pp. 979-986. Karger 10.1159/000490687 <http://dx.doi.org/10.1159/000490687>
Informácie o vydavateľovi: S. Karger AG, 2018.
Rok vydania: 2018
Predmety: Arterial hypertension, Male, Aged, Antihypertensive Agents/therapeutic use, Awareness, Biphenyl Compounds/therapeutic use, Blood Pressure/drug effects, Blood Pressure Monitoring, Ambulatory/methods, Drug Therapy, Combination/methods, Female, Goals, Humans, Hydrochlorothiazide/therapeutic use, Middle Aged, Self Care/standards, Switzerland, Tetrazoles/therapeutic use, Treatment Outcome, Antihypertensive therapy, Goal attainment, Home blood pressure monitoring, Tolerability, Tetrazoles, 610 Medicine & health, Blood Pressure, Dermatology, 2705 Cardiology and Cardiovascular Medicine, 03 medical and health sciences, 0302 clinical medicine, Diseases of the circulatory (Cardiovascular) system, Antihypertensive Agents, 2727 Nephrology, Biphenyl Compounds, Irbesartan, Blood Pressure Monitoring, Ambulatory, Diseases of the genitourinary system. Urology, 3. Good health, Self Care, Hydrochlorothiazide, RL1-803, RC666-701, 10209 Clinic for Cardiology, Drug Therapy, Combination, RC870-923
Popis: Background/Aims: Despite availability of a broad spectrum of blood pressure (BP)-lowering drugs many hypertensive patients do not attain BP goals. We aimed to evaluate the influence of home blood pressure monitoring (HBPM) on patient’s awareness and attainment of BP goals under antihypertensive treatment with irbesartan alone or in combination with hydro-chlorothiazide. Methods: In total, 1,268 patients with arterial hypertension were enrolled in the Factors Influencing Results in anti-hypertenSive Treatment (FIRST) study by 348 general practitioners and internal medicine specialists across Switzerland. Patients selected for HBPM received detailed information and training on BP self-management. The study endpoints included patient’s awareness and attainment of BP goals, and the efficacy and tolerability of antihypertensive treatment at 3 months. Results: Overall, the mean age was 61±13 years and 616 (49%) were women. The mean systolic/diastolic BP was 161±17/96±11 mmHg, and 239 (19%) patients had diabetes mellitus. 758 (60%) patients were instructed to use HBPM. Both the proportion of patients aware of their BP goals (81% vs. 70%; p< 0.001) and the percentage of patients reaching their BP goal (64% vs. 57%; p=0.028) were higher in those with vs. without HBPM. The mean reduction in systolic/diastolic BP was 23.8/13.2 mmHg. Only 35 (3.0%) patients discontinued antihypertensive therapy. Conclusion: In a large Swiss cohort of patients with arterial hypertension, information and training on BP self-measurement and direct involvement of patients by using HBPM led to improvement in BP control. Treatment with irbesartan alone or in combination with hydrochlorothiazide was well tolerated and markedly reduced BP.
Druh dokumentu: Article
Other literature type
Popis súboru: application/pdf; document.pdf - application/pdf
Jazyk: English
ISSN: 1423-0143
1420-4096
DOI: 10.1159/000490687
DOI: 10.5167/uzh-165637
DOI: 10.7892/boris.124980
Prístupová URL adresa: https://www.karger.com/Article/Pdf/490687
https://pubmed.ncbi.nlm.nih.gov/29940594
https://doaj.org/article/79aec2d97a3d47118508629da37d95fc
https://www.ncbi.nlm.nih.gov/pubmed/29940594
https://doaj.org/article/79aec2d97a3d47118508629da37d95fc
https://boris.unibe.ch/124980/
https://serval.unil.ch/notice/serval:BIB_BBBF0FB92D1B
https://serval.unil.ch/resource/serval:BIB_BBBF0FB92D1B.P002/REF.pdf
https://serval.unil.ch/notice/serval:BIB_BBBF0FB92D1B
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_BBBF0FB92D1B2
https://boris.unibe.ch/124980/
Rights: CC BY NC ND
Prístupové číslo: edsair.doi.dedup.....4d0bff78345ca36725f857d0dba0f945
Databáza: OpenAIRE
Popis
Abstrakt:Background/Aims: Despite availability of a broad spectrum of blood pressure (BP)-lowering drugs many hypertensive patients do not attain BP goals. We aimed to evaluate the influence of home blood pressure monitoring (HBPM) on patient’s awareness and attainment of BP goals under antihypertensive treatment with irbesartan alone or in combination with hydro-chlorothiazide. Methods: In total, 1,268 patients with arterial hypertension were enrolled in the Factors Influencing Results in anti-hypertenSive Treatment (FIRST) study by 348 general practitioners and internal medicine specialists across Switzerland. Patients selected for HBPM received detailed information and training on BP self-management. The study endpoints included patient’s awareness and attainment of BP goals, and the efficacy and tolerability of antihypertensive treatment at 3 months. Results: Overall, the mean age was 61±13 years and 616 (49%) were women. The mean systolic/diastolic BP was 161±17/96±11 mmHg, and 239 (19%) patients had diabetes mellitus. 758 (60%) patients were instructed to use HBPM. Both the proportion of patients aware of their BP goals (81% vs. 70%; p< 0.001) and the percentage of patients reaching their BP goal (64% vs. 57%; p=0.028) were higher in those with vs. without HBPM. The mean reduction in systolic/diastolic BP was 23.8/13.2 mmHg. Only 35 (3.0%) patients discontinued antihypertensive therapy. Conclusion: In a large Swiss cohort of patients with arterial hypertension, information and training on BP self-measurement and direct involvement of patients by using HBPM led to improvement in BP control. Treatment with irbesartan alone or in combination with hydrochlorothiazide was well tolerated and markedly reduced BP.
ISSN:14230143
14204096
DOI:10.1159/000490687