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Muscle ultrasound in myopathies

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Bibliographic Details
Title: Muscle ultrasound in myopathies
Authors: Vicino, A., Veltsista, D., van Alfen, N.
Source: Curr Opin Neurol
Current Opinion in Neurology, 37, 5, pp. 549-557
Current opinion in neurology, vol. 37, no. 5, pp. 549-557
Publisher Information: Ovid Technologies (Wolters Kluwer Health), 2024.
Publication Year: 2024
Subject Terms: Neurology - Radboud University Medical Center - DCMN, Muscular Diseases, Humans, Ultrasonography/methods, Muscle, Skeletal/diagnostic imaging, Muscle, Skeletal/pathology, Muscular Diseases/diagnostic imaging, MUSCULAR DISEASE: Edited by Shahram Attarian, Muscle, Skeletal, Ultrasonography, 3. Good health
Description: Purpose of review This review highlights recent developments in the field of muscle ultrasound (MUS) for the diagnosis and follow up of muscle disorders. Recent findings The diagnostic screening capacity of quantitative grayscale analysis is still sufficient to assess children suspected of a neuromuscular disorder. A combination of visual and quantitative assessment is advised for optimal interpretation. MUS was more sensitive but less specific than MRI for detecting pathology in limb girdle dystrophies and inflammatory myopathies. New techniques such as shearwave elastography and artificial intelligence algorithms for automated image segmentation show promise but need further development for use in everyday practice. Muscle ultrasound has high correlations with clinical measures of function in skeletal and respiratory muscles and the orofacial region, in most of the myopathies and dystrophies studied. Over time, imaging changes precede changes in clinical status, making them attractive for biomarker use in trials. In Duchenne muscular dystrophy MUS was also responsive to the effects of steroid treatment. Summary Muscle ultrasound is a sensitive technique to diagnose and follow up of skeletal, facial and respiratory muscles in neuromuscular disorders. Its role is both complementary to and partially overlapping with that of MRI.
Document Type: Article
Other literature type
File Description: application/pdf
Language: English
ISSN: 1473-6551
1350-7540
DOI: 10.1097/wco.0000000000001306
Access URL: https://pubmed.ncbi.nlm.nih.gov/39051427
https://hdl.handle.net/https://repository.ubn.ru.nl/handle/2066/310398
https://doi.org/10.1097/WCO.0000000000001306
https://hdl.handle.net/2066/310398
https://repository.ubn.ru.nl//bitstream/handle/2066/310398/310398.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_40C0B52A200E1
https://serval.unil.ch/notice/serval:BIB_40C0B52A200E
https://serval.unil.ch/resource/serval:BIB_40C0B52A200E.P001/REF.pdf
Rights: CC BY
URL: http://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 (http://creativecommons.org/licenses/by/4.0/)
Accession Number: edsair.doi.dedup.....466df6dde2de9dc1259b7a7ea2fce50c
Database: OpenAIRE
Description
Abstract:Purpose of review This review highlights recent developments in the field of muscle ultrasound (MUS) for the diagnosis and follow up of muscle disorders. Recent findings The diagnostic screening capacity of quantitative grayscale analysis is still sufficient to assess children suspected of a neuromuscular disorder. A combination of visual and quantitative assessment is advised for optimal interpretation. MUS was more sensitive but less specific than MRI for detecting pathology in limb girdle dystrophies and inflammatory myopathies. New techniques such as shearwave elastography and artificial intelligence algorithms for automated image segmentation show promise but need further development for use in everyday practice. Muscle ultrasound has high correlations with clinical measures of function in skeletal and respiratory muscles and the orofacial region, in most of the myopathies and dystrophies studied. Over time, imaging changes precede changes in clinical status, making them attractive for biomarker use in trials. In Duchenne muscular dystrophy MUS was also responsive to the effects of steroid treatment. Summary Muscle ultrasound is a sensitive technique to diagnose and follow up of skeletal, facial and respiratory muscles in neuromuscular disorders. Its role is both complementary to and partially overlapping with that of MRI.
ISSN:14736551
13507540
DOI:10.1097/wco.0000000000001306