Association between the EAT-Lancet Diet, Incidence of Cardiovascular Events, and All-Cause Mortality: Results from a Swiss Cohort

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Title: Association between the EAT-Lancet Diet, Incidence of Cardiovascular Events, and All-Cause Mortality: Results from a Swiss Cohort
Authors: Martins, L.B., Gamba, M., Stubbendorff, A., Gasser, N., Löbl, L., Stern, F., Ericson, U., Marques-Vidal, P., Vuilleumier, S., Chatelan, A.
Source: The Journal of nutrition, vol. 155, no. 2, pp. 483-491
Publisher Information: Elsevier BV, 2025.
Publication Year: 2025
Subject Terms: Male, Adult, Cardiometabolic Health, EAT-Lancet Diet, Incidence, Middle Aged, Cardiovascular disease, Diet, Cohort Studies, Cardiovascular Diseases, Humans, Cardiovascular Diseases/mortality, Switzerland/epidemiology, Female, Prospective Studies, Aged, Diet, Healthy, EAT-Lancet diet, cardiometabolic health, cardiovascular disease, mortality, nutrition, sustainable diets, Sustainable Diets, Mortality, Switzerland, Nutrition
Description: Background An unhealthy diet is a major contributor to several noncommunicable diseases, including cardiovascular diseases (CVD), the leading cause of death worldwide. Additionally, our food system has significant impacts on the environment. The EAT-Lancet Commission has recommended a healthy diet that preserves global environmental resources.Objective This prospective study evaluated the associations between adherence to the EAT-Lancet diet and the incidence of cardiovascular events and all-cause mortality in a Swiss cohort.Methods We analyzed data from the CoLaus|PsyCoLaus cohort study (n = 3,866). Dietary intake was assessed using a semiquantitative food frequency questionnaire. The EAT-Lancet adherence score was calculated based on the recommended intake and reference intervals of 12 food components, ranging from 0 to 39 points. Participants were categorized into low-, medium-, and high-adherence groups according to score tertiles. We used Cox Proportional Hazards regressions to assess the association between diet adherence, incident cardiovascular events and all-cause mortality.Results During a mean follow-up of 7.9 years (SD, ±2.0), 294 individuals (7.6%) from our initial sample experienced a first cardiovascular event, and 264 (6.8%) died. Compared with the low-adherence group, the adjusted hazard ratios for all-cause mortality were 0.88 (95% CI: 0.66-1.17) and 0.70 (95% CI: 0.49-0.98) for the medium- and high-adherence groups, respectively (p for trend = 0.04). We observed no association between adherence groups and cardiovascular events.Conclusions In a Swiss cohort, high adherence to the EAT-Lancet diet was associated with a potential 30% lower risk of overall mortality. However, no association was found between the EAT-Lancet diet and cardiovascular events.
Document Type: Article
Other literature type
File Description: application/pdf
Language: English
ISSN: 0022-3166
DOI: 10.1016/j.tjnut.2024.12.012
DOI: 10.48620/78859
Access URL: https://pubmed.ncbi.nlm.nih.gov/39742968
https://serval.unil.ch/notice/serval:BIB_09BBDCA475AA
https://serval.unil.ch/resource/serval:BIB_09BBDCA475AA.P001/REF.pdf
http://nbn-resolving.org/urn/resolver.pl?urn=urn:nbn:ch:serval-BIB_09BBDCA475AA9
Rights: CC BY
Accession Number: edsair.doi.dedup.....4413271b9af8b76724a47ba5f6d0a844
Database: OpenAIRE
Description
Abstract:Background An unhealthy diet is a major contributor to several noncommunicable diseases, including cardiovascular diseases (CVD), the leading cause of death worldwide. Additionally, our food system has significant impacts on the environment. The EAT-Lancet Commission has recommended a healthy diet that preserves global environmental resources.Objective This prospective study evaluated the associations between adherence to the EAT-Lancet diet and the incidence of cardiovascular events and all-cause mortality in a Swiss cohort.Methods We analyzed data from the CoLaus|PsyCoLaus cohort study (n = 3,866). Dietary intake was assessed using a semiquantitative food frequency questionnaire. The EAT-Lancet adherence score was calculated based on the recommended intake and reference intervals of 12 food components, ranging from 0 to 39 points. Participants were categorized into low-, medium-, and high-adherence groups according to score tertiles. We used Cox Proportional Hazards regressions to assess the association between diet adherence, incident cardiovascular events and all-cause mortality.Results During a mean follow-up of 7.9 years (SD, ±2.0), 294 individuals (7.6%) from our initial sample experienced a first cardiovascular event, and 264 (6.8%) died. Compared with the low-adherence group, the adjusted hazard ratios for all-cause mortality were 0.88 (95% CI: 0.66-1.17) and 0.70 (95% CI: 0.49-0.98) for the medium- and high-adherence groups, respectively (p for trend = 0.04). We observed no association between adherence groups and cardiovascular events.Conclusions In a Swiss cohort, high adherence to the EAT-Lancet diet was associated with a potential 30% lower risk of overall mortality. However, no association was found between the EAT-Lancet diet and cardiovascular events.
ISSN:00223166
DOI:10.1016/j.tjnut.2024.12.012