Increasing participation in cervical cancer screening: Offering a HPV self‐test to long‐term non‐attendees as part of RACOMIP, a Swedish randomized controlled trial: Offering a HPV self-test to long-term non-attendees as part of RACOMIP, a Swedish randomized controlled trial
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| Titel: | Increasing participation in cervical cancer screening: Offering a HPV self‐test to long‐term non‐attendees as part of RACOMIP, a Swedish randomized controlled trial: Offering a HPV self-test to long-term non-attendees as part of RACOMIP, a Swedish randomized controlled trial |
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| Autoren: | Broberg, Gudrun, Gyrd-Hansen, Dorte, Jonasson, JM, Ryd, M-L, Holtenman, M, Miltom, I, Strander, Bjorn |
| Quelle: | Broberg, G, Gyrd-Hansen, D, Jonasson, JM, Ryd, M-L, Holtenman, M, Miltom, I & Strander, B 2014, ' Increasing participation in cervical cancer screening : Offering a HPV self-test to long-term non-attendees as part of RACOMIP, a Swedish randomized controlled trial ', International Journal of Cancer, vol. 134, no. 9, pp. 2223-2230 . https://doi.org/10.1002/ijc.28545 |
| Verlagsinformationen: | Wiley, 2013. |
| Publikationsjahr: | 2013 |
| Schlagwörter: | mass screening, Adult, HPV, Cost-Benefit Analysis, Uterine Cervical Neoplasms, cervical intraepithelial neoplasia, 7. Clean energy, 03 medical and health sciences, 0302 clinical medicine, Uterine Cervical Neoplasms/diagnosis, Humans, Papillomavirus Infections/complications, Self Care/economics, Early Detection of Cancer, Sweden, Vaginal Smears, Papillomavirus Infections, papanicolaou smear, Middle Aged, 16. Peace & justice, Telephone, 3. Good health, Self Care, Early Detection of Cancer/economics, Female, non-attendance, Papanicolaou Test |
| Beschreibung: | RACOMIP is a population‐based, randomized trial of the effectiveness and cost‐effectiveness of different interventions aimed at increasing participation in a well‐run cervical cancer screening program in western Sweden. In this article, we report results from one intervention, offering non‐attendees a high‐risk human papillomavirus (HPV) self‐test. Comparison was made with standard screening invitation routine or standard routine plus a telephone call. Women (8,800), aged 30–62, were randomly selected among women without a registered Pap smear in the two latest screening rounds. These women were randomized 1:5:5 to one of three arms: 800 were offered a high‐risk HPV self‐test, 4,000 were randomized to a telephone call (reported previously) and 4,000 constituted a control group (standard screening invitation routine). Results were based on intention to treat analysis and cost‐effectiveness was calculated as marginal cost per cancer case prevented. The endpoint was the frequency of testing. The total response rate in the self‐testing arm was 24.5%, significantly higher than in the telephone arm (18%, RR 1.36, 95% CI 1.19–1.57) and the control group (10.6%, RR 2.33, 95% CI 2.00–2.71). All nine women who tested positive for high‐risk HPV attended for a cervical smear and colposcopy. From the health‐care sector perspective, the intervention will most likely lead to no additional cost. Offering a self‐test for HPV as an alternative to Pap smears increases participation among long‐term non‐attendees. Offering various screening options can be a successful method for increasing participation in this group. |
| Publikationsart: | Article |
| Sprache: | English |
| ISSN: | 1097-0215 0020-7136 |
| DOI: | 10.1002/ijc.28545 |
| Zugangs-URL: | https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijc.28545 https://pubmed.ncbi.nlm.nih.gov/24127304 https://pubmed.ncbi.nlm.nih.gov/24127304/ https://www.onlinelibrary.wiley.com/doi/pdf/10.1002/ijc.28545 https://portal.findresearcher.sdu.dk/da/publications/increasing-participation-in-cervical-cancer-screening-offering-a- https://www.ncbi.nlm.nih.gov/pubmed/24127304 https://onlinelibrary.wiley.com/doi/full/10.1002/ijc.28545 https://portal.findresearcher.sdu.dk/da/publications/b5da8f82-bc04-4676-a375-356f02538ce8 https://portal.findresearcher.sdu.dk/da/publications/b5da8f82-bc04-4676-a375-356f02538ce8 https://doi.org/10.1002/ijc.28545 |
| Rights: | Wiley Online Library User Agreement |
| Dokumentencode: | edsair.doi.dedup.....43c807c671bc1bb8e635f451438e7b8d |
| Datenbank: | OpenAIRE |
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Nájsť tento článok vo Web of Science | Abstract: | RACOMIP is a population‐based, randomized trial of the effectiveness and cost‐effectiveness of different interventions aimed at increasing participation in a well‐run cervical cancer screening program in western Sweden. In this article, we report results from one intervention, offering non‐attendees a high‐risk human papillomavirus (HPV) self‐test. Comparison was made with standard screening invitation routine or standard routine plus a telephone call. Women (8,800), aged 30–62, were randomly selected among women without a registered Pap smear in the two latest screening rounds. These women were randomized 1:5:5 to one of three arms: 800 were offered a high‐risk HPV self‐test, 4,000 were randomized to a telephone call (reported previously) and 4,000 constituted a control group (standard screening invitation routine). Results were based on intention to treat analysis and cost‐effectiveness was calculated as marginal cost per cancer case prevented. The endpoint was the frequency of testing. The total response rate in the self‐testing arm was 24.5%, significantly higher than in the telephone arm (18%, RR 1.36, 95% CI 1.19–1.57) and the control group (10.6%, RR 2.33, 95% CI 2.00–2.71). All nine women who tested positive for high‐risk HPV attended for a cervical smear and colposcopy. From the health‐care sector perspective, the intervention will most likely lead to no additional cost. Offering a self‐test for HPV as an alternative to Pap smears increases participation among long‐term non‐attendees. Offering various screening options can be a successful method for increasing participation in this group. |
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| ISSN: | 10970215 00207136 |
| DOI: | 10.1002/ijc.28545 |