Predicting pulmonary hypertension in sarcoidosis; value of PH probability on echocardiography
Uložené v:
| Názov: | Predicting pulmonary hypertension in sarcoidosis; value of PH probability on echocardiography |
|---|---|
| Autori: | M. P. Huitema, A. L. M. Bakker, J. J. Mager, R. J. Snijder, B. J. W. M. Rensing, M. J. Swaans, J. C. Grutters, M. C. Post |
| Prispievatelia: | Longziekten, Infection & Immunity, Team Medisch |
| Zdroj: | The International Journal of Cardiovascular Imaging. 36:1497-1505 |
| Informácie o vydavateľovi: | Springer Science and Business Media LLC, 2020. |
| Rok vydania: | 2020 |
| Predmety: | Adult, Male, Sarcoidosis, Hypertension, Pulmonary, Interstitial lung disease, Atrial Function, Right, Pulmonary Artery, Pulmonary hypertension, 03 medical and health sciences, 0302 clinical medicine, Sarcoidosis, Pulmonary, Right heart catheterisation, Predictive Value of Tests, Risk Factors, Journal Article, Humans, Hypertension, Pulmonary/diagnostic imaging, Arterial Pressure, Prospective Studies, Pulmonary Artery/diagnostic imaging, Aged, Sarcoidosis, Pulmonary/complications, Middle Aged, Prognosis, 3. Good health, Radiology Nuclear Medicine and imaging, Echocardiography, Disease Progression, Ventricular Function, Right, Female, Cardiology and Cardiovascular Medicine |
| Popis: | Pulmonary hypertension (PH) is a well-recognised complication of sarcoidosis. Non-invasive diagnosis is challenging due to limited accuracy of echocardiography in interstitial lung disease. This study evaluates the value of echocardiographic PH probability for diagnosing PH in pulmonary sarcoidosis. All consecutive patients between August 2015 and November 2018 were prospectively screened for PH, and classified as low, intermediate or high PH probability. Patients with intermediate or high PH probability were referred for right heart catheterisation. PH was defined as a mean pulmonary artery pressure of ≥ 25 mm Hg. Additional data on pulmonary function and chest-CT was collected. Of all 479 patients, PH was present in 17 and absent in 19 patients. Six patients refused right heart catheterisation. PH was present in 33% and 75% of patients with intermediate and high PH probability respectively (n = 36). TRV max was measurable in 46% of all patients. Measurability did not correlate with FVC% predicted or presence of significant fibrosis. In intermediate and high PH probability, TRV max 3.4 confirmed PH in all patients. If TRV max was absent or in between 2.9 and 3.4, secondary echocardiographic signs were not able to improve the diagnostic accuracy. PH is unlikely in patients with a TRV max 3.4 m/s. Discrimination is challenging if the TRV max is between 2.9-3.4 m/s or absent. Additional secondary signs do not improve discrimination. Decision making for further investigations should be made by an expert team. |
| Druh dokumentu: | Article |
| Popis súboru: | application/pdf |
| Jazyk: | English |
| ISSN: | 1573-0743 1569-5794 |
| DOI: | 10.1007/s10554-020-01859-9 |
| Prístupová URL adresa: | https://pubmed.ncbi.nlm.nih.gov/32350704 https://pubmed.ncbi.nlm.nih.gov/32350704/ https://www.ncbi.nlm.nih.gov/pubmed/32350704 https://link.springer.com/article/10.1007/s10554-020-01859-9 https://dspace.library.uu.nl/handle/1874/442100 |
| Rights: | Springer TDM |
| Prístupové číslo: | edsair.doi.dedup.....42a1163cbcde0cc96d7aa9393d3087c3 |
| Databáza: | OpenAIRE |
Full Text Finder 
Nájsť tento článok vo Web of Science | Abstrakt: | Pulmonary hypertension (PH) is a well-recognised complication of sarcoidosis. Non-invasive diagnosis is challenging due to limited accuracy of echocardiography in interstitial lung disease. This study evaluates the value of echocardiographic PH probability for diagnosing PH in pulmonary sarcoidosis. All consecutive patients between August 2015 and November 2018 were prospectively screened for PH, and classified as low, intermediate or high PH probability. Patients with intermediate or high PH probability were referred for right heart catheterisation. PH was defined as a mean pulmonary artery pressure of ≥ 25 mm Hg. Additional data on pulmonary function and chest-CT was collected. Of all 479 patients, PH was present in 17 and absent in 19 patients. Six patients refused right heart catheterisation. PH was present in 33% and 75% of patients with intermediate and high PH probability respectively (n = 36). TRV max was measurable in 46% of all patients. Measurability did not correlate with FVC% predicted or presence of significant fibrosis. In intermediate and high PH probability, TRV max 3.4 confirmed PH in all patients. If TRV max was absent or in between 2.9 and 3.4, secondary echocardiographic signs were not able to improve the diagnostic accuracy. PH is unlikely in patients with a TRV max 3.4 m/s. Discrimination is challenging if the TRV max is between 2.9-3.4 m/s or absent. Additional secondary signs do not improve discrimination. Decision making for further investigations should be made by an expert team. |
|---|---|
| ISSN: | 15730743 15695794 |
| DOI: | 10.1007/s10554-020-01859-9 |