Implications of cognitive and daily living capabilities on early type 2 diabetes management: a preliminary case–control study
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| Titel: | Implications of cognitive and daily living capabilities on early type 2 diabetes management: a preliminary case–control study |
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| Autoren: | Romina Mahmoudi, Farzin Kamari, Reza Naghdi Sadeh, Amirreza Naseri, Vahideh Sadra |
| Quelle: | Eur J Med Res European Journal of Medical Research, Vol 29, Iss 1, Pp 1-9 (2024) |
| Verlagsinformationen: | Springer Science and Business Media LLC, 2024. |
| Publikationsjahr: | 2024 |
| Schlagwörter: | Male, Adult, Montreal cognitive assessment, 03 medical and health sciences, Diabetes mellitus, Cognition, 0302 clinical medicine, Activities of Daily Living, Instrumental activities of daily living, Treatment adherence, Humans, Hypoglycemic Agents, Cognitive Dysfunction, Aged, Glycated Hemoglobin, Research, Middle Aged, 3. Good health, Diabetes Mellitus, Type 2, Case-Control Studies, Cognition/drug effects [MeSH], Cognition/physiology [MeSH], Dementia, Female [MeSH], Aged [MeSH], Adult [MeSH], Humans [MeSH], Cognitive Dysfunction/etiology [MeSH], Diabetes Mellitus, Type 2/drug therapy [MeSH], Middle Aged [MeSH], Diabetes Mellitus, Type 2/blood [MeSH], Male [MeSH], Activities of Daily Living [MeSH], Case-Control Studies [MeSH], Hypoglycemic Agents/therapeutic use [MeSH], Glycated Hemoglobin/analysis [MeSH], Hypoglycemic Agents/administration, Diabetes Mellitus, Type 2/psychology [MeSH], Medicine, Female |
| Beschreibung: | BackgroundAdherence to the transition from oral agents to insulin injections in Type 2 Diabetes Mellitus therapy varies among patients and is not uniformly successful, leading to suboptimal glycemic control in certain cases. This study aims to investigate the potential correlation between cognitive and daily functional capabilities and glycemic control in middle-aged to older adults (40–74 years old) diagnosed with Type 2 Diabetes Mellitus for less than 10 years, specifically those who have recently transitioned to insulin injections and have lower education levels within the context of a developing country.MethodsA case–control study was conducted with 30 poorly controlled diabetes mellitus (PCDM) patients recognized by HbA1c levels > 8% compared to 30 fairly controlled diabetes mellitus (FCDM) patients with HbA1c levels ≤ 8%. Basic Montreal Cognitive Assessment (MoCA-B) score of less than 27 was investigated as the exposure among two groups. Additionally, intra- and inter-battery correlations were assessed among MoCA-B and Instrumental Activities of Daily Living (IADL) domains using Pearson’sr.ResultsThe primary outcomes showed no crude difference between MoCA-B scores in the two diabetic groups (p-value = 0.82). However, after adjusting for age, education, and IADL scores, cognitive decline in the less-educated younger elderly with high IADL scores demonstrated an unexpected protective effect against PCDM (p-value p-values of p-values ConclusionSuperior performance in certain cognitive domains is linked to better glycemic control. Still, since assessing cognitive domains may be timely in clinical routine, a potential rapid approach might be taken by assessing patients’ instrumental abilities to use cell phone or manage medications. Future studies including a larger sample size and a broader spectrum of psychosocial factors are needed to elaborate on our findings. |
| Publikationsart: | Article Other literature type |
| Sprache: | English |
| ISSN: | 2047-783X |
| DOI: | 10.1186/s40001-024-01925-1 |
| DOI: | 10.15496/publikation-101052 |
| Zugangs-URL: | https://pubmed.ncbi.nlm.nih.gov/38890763 https://doaj.org/article/2b0a98e83ce542b499182363e94f7abc https://repository.publisso.de/resource/frl:6521527 |
| Rights: | CC BY URL: http://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (http://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (http://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
| Dokumentencode: | edsair.doi.dedup.....3f17d073bff788fc461f7401184423a8 |
| Datenbank: | OpenAIRE |
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Nájsť tento článok vo Web of Science | Abstract: | BackgroundAdherence to the transition from oral agents to insulin injections in Type 2 Diabetes Mellitus therapy varies among patients and is not uniformly successful, leading to suboptimal glycemic control in certain cases. This study aims to investigate the potential correlation between cognitive and daily functional capabilities and glycemic control in middle-aged to older adults (40–74 years old) diagnosed with Type 2 Diabetes Mellitus for less than 10 years, specifically those who have recently transitioned to insulin injections and have lower education levels within the context of a developing country.MethodsA case–control study was conducted with 30 poorly controlled diabetes mellitus (PCDM) patients recognized by HbA1c levels > 8% compared to 30 fairly controlled diabetes mellitus (FCDM) patients with HbA1c levels ≤ 8%. Basic Montreal Cognitive Assessment (MoCA-B) score of less than 27 was investigated as the exposure among two groups. Additionally, intra- and inter-battery correlations were assessed among MoCA-B and Instrumental Activities of Daily Living (IADL) domains using Pearson’sr.ResultsThe primary outcomes showed no crude difference between MoCA-B scores in the two diabetic groups (p-value = 0.82). However, after adjusting for age, education, and IADL scores, cognitive decline in the less-educated younger elderly with high IADL scores demonstrated an unexpected protective effect against PCDM (p-value p-values of p-values ConclusionSuperior performance in certain cognitive domains is linked to better glycemic control. Still, since assessing cognitive domains may be timely in clinical routine, a potential rapid approach might be taken by assessing patients’ instrumental abilities to use cell phone or manage medications. Future studies including a larger sample size and a broader spectrum of psychosocial factors are needed to elaborate on our findings. |
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| ISSN: | 2047783X |
| DOI: | 10.1186/s40001-024-01925-1 |