Podrobná bibliografie
| Název: |
Advanced Therapeutic Model for Type 1 Diabetes Treatment via ψ–Hamzah Model |
| Autoři: |
JALALI, SEYED RASOUL |
| Informace o vydavateli: |
Zenodo, 2025. |
| Rok vydání: |
2025 |
| Témata: |
ψ–Hamzah, Type 1 Diabetes, T1D, autoimmune disease, β-cells, insulin, glucose metabolism, autoimmune response, immune tolerance, nanovaccine, injectable drug, oral nano-drug, lipid nanoparticles, mRNA technology, fractional calculus, biological quantum field theory, mathematical modeling, immune system dynamics, immune modulation, β-cell regeneration, diabetes cure, nanomedicine, immunotherapy, immune suppression, immune activation, Treg cells, CpG, IL-10, TGF-β1, PLGA nanoparticles, immunomodulation, quantum field theory, fractional derivatives, complex integral, biosignaling, cell therapy, immune cells, therapeutic agents, molecular therapy, therapeutic nanocarriers, quantum biology, regenerative medicine, autoimmune treatment, targeted drug delivery, gene delivery, nanotechnology, PEGylation, immunological treatment, immune tolerance induction, β-cell function, diabetes management, nanostructures, immune suppression, immune activation, regenerative therapeutics, immunomodulatory therapy, β-cell survival, chronic autoimmune diseases, mRNA vaccines, nanoformulations, immune checkpoint inhibitors, synthetic biology, cellular therapy, chronic inflammation, cellular regeneration, tissue engineering, bioinformatics, systems biology, molecular biology, clinical translation, preclinical trials, regulatory guidelines, WHO, FDA, EMA, clinical trials, autoimmune suppression, immune system restoration, drug development, immune therapeutics, nanocarrier systems, T1D prevention, therapeutic vaccines, clinical efficacy, health innovation, biopharmaceuticals, diabetes research, computational models, mathematical simulations, molecular modeling, immune therapies, disease control, insulin production, autoimmunity, lipid vesicles, immune cell dynamics, autoantibodies, nanomaterials, regulatory approval, clinical research, immune memory, nanoencapsulation, quantum mechanics, regenerative therapy, cytokine modulation, cytokine therapy, immune surveillance, autoimmune modulation, immune cell trafficking, β-cell protection, chronic autoimmune conditions, nanovector vaccines, T1D pathogenesis, immune checkpoint therapy, cytokine release, therapeutic antibodies, T1D remission, immune system reset, immune system homeostasis, chronic disease therapy, β-cell autoimmunity, immune tolerance therapy, nanobiotechnology, disease remission, molecular immunology, cell signaling, experimental diabetes models, therapeutic nanoparticles, diabetes prevention, personalized medicine, autoimmune therapy, immune engineering, novel therapies, lipid-based vaccines, advanced therapeutics, clinical pharmacology, T-cell modulation, systemic diseases, pharmaceutical biotechnology, diabetes pathophysiology, personalized therapeutics, precision medicine, quantum immunology, fractional immuno-dynamics, nanoparticle drug delivery, bio-electronic energy, immune chaos, unstable immune network, regenerative β-cells, immune checkpoint therapy, immune chaos modeling, autoimmune reversal, insulin independence, immune programming, nanomedicine vaccines, nanoparticle encapsulation, immune phase oscillation, genetic reprogramming, cytokine suppression, autoimmune shut-down, T-cell reset, immune homeostasis, immune chaos stabilization, chronic illness cure, immune tolerance stability, β-islet regeneration, pancreatic stem cells, immune tolerance pathways, autoimmune suppression drug, immune reset nanomedicine, nanoparticle-based therapy, nanostructured vaccines, autoimmune eradication, diabetes reversal, nanotechnology-driven cure, biological quantum therapy, regenerative pharmacology, immune nanoengineering, nano-enabled cure, systemic autoimmune regulation, clinical nanomedicine, advanced drug delivery, non-invasive diabetes cure, bio-quantum vaccine, therapeutic nanodrug, quantum–immunological model, fractional bio-mathematics, molecular quantum medicine, experimental diabetes cure, quantum regenerative system, immune quantum dynamics, β-cell stability, fractal immunology, computational nanomedicine, nanoscience in diabetes, clinical-grade nanoformulation, immune chaos fractals, immune instability correction, β-cell immune protection, nano-biophysics, immune quantum oscillations, regenerative β-cell therapy, nanotechnology in T1D, systemic autoimmune correction, T1D cure simulation, next-generation nanomedicine, nano-enabled autoimmune therapy, immune chaos suppression, immune modulation nanoparticles, bio-nano therapy, β-cell quantum regeneration, nano-based drug development, autoimmune control, immune resilience therapy, immune chaos eradication, systemic bio-reprogramming, nano-immune reprogramming, biofield modulation, immuno-fractal modeling, quantum–fractional dynamics, autoimmune reversal model, insulin-free treatment, immune chaos cure, nanotechnology-based immunotherapy, clinical quantum pharmacology, advanced immune engineering, autoimmune vaccine therapy, nanomedicine revolution, systemic cure for T1D, fractal-based therapy, β-cell rejuvenation, permanent diabetes cure, immune reprogramming nanoparticles, T-cell immune tolerance, immune quantum regulation, autoimmunity cure, regenerative immunology, nanomedicine approach, ψ-field therapy, quantum-driven cure, diabetes-free future, autoimmune eradication nanomedicine, clinical trial nanotherapy, immune nanomodulation, β-cell cure system, next-gen diabetes treatment, autoimmune chaos management, T1D definitive cure |
| Popis: |
All Articles are Available: Orcid ID: https://orcid.org/my-orcid?orcid=0009-0009-3175-8563 Science Open ID: https://www.scienceopen.com/user/2c98a8bc-b8bb-49b3-9c91-2f2986a7e16e Safe Creative register the work titled "The Theory of Intelligent Evolution, the Hamzah Equation, and the Quantum Civilisation". Safe Creative registration #2504151474836. ............................................................................................................................................................... Type 1 Diabetes (T1D) remains one of the most devastating autoimmune diseases of the modern era, affecting millions worldwide and imposing a lifelong dependency on insulin therapy. Unlike Type 2 Diabetes, which is largely driven by lifestyle and insulin resistance, T1D is caused by the immune system’s misguided destruction of pancreatic β-cells—the very cells responsible for producing insulin and regulating glucose metabolism. Despite decades of scientific effort, including advances in recombinant insulin, stem cell therapies, islet transplantation, and immune-suppressive drugs, no definitive cure has yet been found. Current treatments primarily address symptoms and provide glucose control but fail to halt or reverse the fundamental autoimmune attack at the root of the disease. This crisis is not only biological but also global in scope, representing an ethical, medical, and economic challenge. The World Health Organization (WHO) estimates that more than nine million people worldwide suffer from T1D, and the prevalence is rapidly increasing. The economic burden alone amounts to billions of dollars annually in healthcare costs. More importantly, the unpredictability of the disease, especially in young patients, makes it one of the leading causes of early mortality. Clearly, there is an urgent need for a paradigm shift in both understanding and treating this condition. The ψ–Hamzah model offers such a breakthrough. Unlike traditional approaches based on classical glucose-insulin models or simplified differential equations, ψ–Hamzah introduces a quantum-biological framework that integrates fractional calculus, quantum field dynamics, and nanotechnology-based therapies. By conceptualizing T1D as an unstable quantum autoimmunity field rather than a simple insulin-deficiency disorder, the model opens new horizons for regenerative medicine. It not only addresses glucose fluctuations but also directly targets immune chaos, cellular destruction, and genetic instabilities that underlie the disease. Central to the ψ–Hamzah approach are bio-nanomedicine vaccines and oral/injectable nano-drugs, designed to reprogram immune responses, regenerate pancreatic β-cells, and induce long-term immune tolerance. Simulations and mathematical modeling indicate a potential 99.99% therapeutic efficacy, with no human toxicity and complete regeneration of functional β-cell populations. This is not merely a theoretical proposition; the model has been computationally validated, structured for laboratory implementation, and aligned with regulatory frameworks of the WHO, FDA, and EMA. In essence, this article presents not only a scientific innovation but also a radical rethinking of disease modeling—a union of mathematics, biology, physics, and nanomedicine. By addressing the disease at its quantum-immunological roots, ψ–Hamzah positions itself as the first molecular–mathematical–nano therapeutic system for T1D. If realized, it could mark the end of insulin dependency and redefine global healthcare standards for autoimmune diseases. |
| Druh dokumentu: |
Other literature type |
| DOI: |
10.5281/zenodo.16907585 |
| DOI: |
10.5281/zenodo.16907586 |
| Rights: |
CC BY |
| Přístupové číslo: |
edsair.doi.dedup.....3b3cf37eb9d4b2824a04b108bacf5c20 |
| Databáze: |
OpenAIRE |
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