Genetic Architecture of Resistance to Stripe Rust in a Global Winter Wheat Germplasm Collection
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| Názov: | Genetic Architecture of Resistance to Stripe Rust in a Global Winter Wheat Germplasm Collection |
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| Autori: | Bulli, Peter, Zhang, Junli, Chao, Shiaoman, Chen, Xianming, Pumphrey, Michael |
| Zdroj: | G3 (Bethesda) G3: Genes, Genomes, Genetics, Vol 6, Iss 8, Pp 2237-2253 (2016) G3: Genes, Genomes, Genetics, vol 6, iss 8 |
| Informácie o vydavateľovi: | Oxford University Press (OUP), 2016. |
| Rok vydania: | 2016 |
| Predmety: | 0301 basic medicine, Plant Diseases - genetics, disease resistance, Genotype, Quantitative Trait Loci, QTL-tag SNP, Plant Biology, genetics of immunity, QH426-470, Polymorphism, Single Nucleotide, 03 medical and health sciences, Disease Resistance - genetics, Genetics, Triticum - microbiology, Quantitative Trait Loci - genetics, Polymorphism, association mapping, Triticum, Disease Resistance, Plant Diseases, 2. Zero hunger, 0303 health sciences, yellow rust, Genetics Of Immunity, Basidiomycota, Human Genome, Statistics, Chromosome Mapping, Single Nucleotide, Triticum - genetics, Biological Sciences, Triticum - growth & development, hexaploid wheat, Plant Breeding, Basidiomycota - genetics, Seed Bank, Biochemistry and cell biology, Plant Diseases - microbiology, Basidiomycota - pathogenicity, Genome-Wide Association Study |
| Popis: | Virulence shifts in populations of Puccinia striiformis f. sp. tritici (Pst), the causal pathogen of wheat stripe rust, are a major challenge to resistance breeding. The majority of known resistance genes are already ineffective against current races of Pst, necessitating the identification and introgression of new sources of resistance. Germplasm core collections that reflect the range of genetic and phenotypic diversity of crop species are ideal platforms for examining the genetic architecture of complex traits such as resistance to stripe rust. We report the results of genetic characterization and genome-wide association analysis (GWAS) for resistance to stripe rust in a core subset of 1175 accessions in the National Small Grains Collection (NSGC) winter wheat germplasm collection, based on genotyping with the wheat 9K single nucleotide polymorphism (SNP) iSelect assay and phenotyping of seedling and adult plants under natural disease epidemics in four environments. High correlations among the field data translated into high heritability values within and across locations. Population structure was evident when accessions were grouped by stripe rust reaction. GWAS identified 127 resistance loci that were effective across at least two environments, including 20 with significant genome-wide adjusted P-values. Based on relative map positions of previously reported genes and QTL, five of the QTL with significant genome-wide adjusted P-values in this study represent potentially new loci. This study provides an overview of the diversity of Pst resistance in the NSGC winter wheat germplasm core collection, which can be exploited for diversification of stripe rust resistance in breeding programs. |
| Druh dokumentu: | Article Other literature type |
| Popis súboru: | application/pdf |
| Jazyk: | English |
| ISSN: | 2160-1836 |
| DOI: | 10.1534/g3.116.028407 |
| Prístupová URL adresa: | https://pubmed.ncbi.nlm.nih.gov/27226168 https://doaj.org/article/b8de53889b934e1ebf98985419b7b22e https://europepmc.org/article/MED/27226168 https://pubmed.ncbi.nlm.nih.gov/27226168/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978880 https://www.g3journal.org/content/6/8/2237 https://core.ac.uk/display/89584001 https://academic.oup.com/g3journal/article/6/8/2237/6054837 https://escholarship.org/content/qt7b49p7hp/qt7b49p7hp.pdf https://escholarship.org/uc/item/7b49p7hp |
| Rights: | OUP Standard Publication Reuse CC BY NC CC BY |
| Prístupové číslo: | edsair.doi.dedup.....390a8910f4bbb775db5b3ea82a8edf48 |
| Databáza: | OpenAIRE |
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Nájsť tento článok vo Web of Science | Abstrakt: | Virulence shifts in populations of Puccinia striiformis f. sp. tritici (Pst), the causal pathogen of wheat stripe rust, are a major challenge to resistance breeding. The majority of known resistance genes are already ineffective against current races of Pst, necessitating the identification and introgression of new sources of resistance. Germplasm core collections that reflect the range of genetic and phenotypic diversity of crop species are ideal platforms for examining the genetic architecture of complex traits such as resistance to stripe rust. We report the results of genetic characterization and genome-wide association analysis (GWAS) for resistance to stripe rust in a core subset of 1175 accessions in the National Small Grains Collection (NSGC) winter wheat germplasm collection, based on genotyping with the wheat 9K single nucleotide polymorphism (SNP) iSelect assay and phenotyping of seedling and adult plants under natural disease epidemics in four environments. High correlations among the field data translated into high heritability values within and across locations. Population structure was evident when accessions were grouped by stripe rust reaction. GWAS identified 127 resistance loci that were effective across at least two environments, including 20 with significant genome-wide adjusted P-values. Based on relative map positions of previously reported genes and QTL, five of the QTL with significant genome-wide adjusted P-values in this study represent potentially new loci. This study provides an overview of the diversity of Pst resistance in the NSGC winter wheat germplasm core collection, which can be exploited for diversification of stripe rust resistance in breeding programs. |
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| ISSN: | 21601836 |
| DOI: | 10.1534/g3.116.028407 |