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Burden of psychiatric and somatic comorbidities in individuals with suicidal behavior: a nationwide Danish registry-based, observational study: A nationwide Danish registry-based, observational study

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Titel: Burden of psychiatric and somatic comorbidities in individuals with suicidal behavior: a nationwide Danish registry-based, observational study: A nationwide Danish registry-based, observational study
Autoren: Mette Reilev, Jens-Jakob Kjer Møller, Elsebeth Stenager, Erik Christiansen
Quelle: Eur Psychiatry
European Psychiatry, Vol 68 (2025)
Verlagsinformationen: Royal College of Psychiatrists, 2025.
Publikationsjahr: 2025
Schlagwörter: Male, Adult, suicide research, Attempted/statistics & numerical data, Adolescent, Denmark, RC435-571, Suicide, Attempted, Comorbidity, Young Adult, Neoplasms, 80 and over, Humans, Registries, Aged, comorbidity burden, Psychiatry, Aged, 80 and over, Mood Disorders, Mental Disorders, Suicide/statistics & numerical data, Registries/statistics & numerical data, Mood Disorders/epidemiology, Middle Aged, Suicide research, Denmark/epidemiology, Suicide, epidemiology, Female, Neoplasms/epidemiology, Mental Disorders/epidemiology, Research Article
Beschreibung: Background Many psychiatric and somatic comorbidities increase the risk of suicidal behavior, but the effect of co-existing comorbidities is sparsely elucidated. We described co-existence of psychiatric and somatic comorbidities and the influence of the combined comorbidity burden on the risk of suicidal behavior. Methods We defined two case populations above 10 years in the Danish health registries: those who 1) died by suicide (2010–2020) and 2) had an incident suicide attempt (2010–2021). Co-existing somatic and psychiatric comorbidities and relative odds of suicidal behavior at increasing comorbidity burden were assessed. Results Among 5.9 million Danish citizens (2021), 6,257 individuals died by suicide whereas 30,570 had an incident suicide attempt. More than half had ≥2 co-existing psychiatric and/or somatic comorbidities. Of those who died by suicide, 18% had co-existing mood disorders and stress disorders, while 5% had both mood disorders and cancer. An 88-fold increase of odds for attempting suicide and a 35-fold increase of odds for suicide were observed among those with the highest combined burden of somatic and psychiatric comorbidities relative to those without. The presence of somatic comorbidities seemed to protect against suicide in older individuals. Conclusions Psychiatric and somatic comorbidities commonly co-exist in individuals with suicidal behavior. Higher combined burden of psychiatric and somatic comorbidities increased the odds of suicidal behavior, though the presence of somatic diseases had a potential protective effect on the risk of suicide in older individuals. This warrants collaboration and enhanced awareness of suicidal behavior risks across somatic and psychiatric departments.
Publikationsart: Article
Other literature type
Sprache: English
ISSN: 1778-3585
0924-9338
DOI: 10.1192/j.eurpsy.2024.1781
Zugangs-URL: https://pubmed.ncbi.nlm.nih.gov/39834204
https://doaj.org/article/95fb5a3e66484b7aa11dc23608be311c
Rights: CC BY
URL: http://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.
Dokumentencode: edsair.doi.dedup.....3862e2b1d784e808fe497d58f0e8d0fd
Datenbank: OpenAIRE
Beschreibung
Abstract:Background Many psychiatric and somatic comorbidities increase the risk of suicidal behavior, but the effect of co-existing comorbidities is sparsely elucidated. We described co-existence of psychiatric and somatic comorbidities and the influence of the combined comorbidity burden on the risk of suicidal behavior. Methods We defined two case populations above 10 years in the Danish health registries: those who 1) died by suicide (2010–2020) and 2) had an incident suicide attempt (2010–2021). Co-existing somatic and psychiatric comorbidities and relative odds of suicidal behavior at increasing comorbidity burden were assessed. Results Among 5.9 million Danish citizens (2021), 6,257 individuals died by suicide whereas 30,570 had an incident suicide attempt. More than half had ≥2 co-existing psychiatric and/or somatic comorbidities. Of those who died by suicide, 18% had co-existing mood disorders and stress disorders, while 5% had both mood disorders and cancer. An 88-fold increase of odds for attempting suicide and a 35-fold increase of odds for suicide were observed among those with the highest combined burden of somatic and psychiatric comorbidities relative to those without. The presence of somatic comorbidities seemed to protect against suicide in older individuals. Conclusions Psychiatric and somatic comorbidities commonly co-exist in individuals with suicidal behavior. Higher combined burden of psychiatric and somatic comorbidities increased the odds of suicidal behavior, though the presence of somatic diseases had a potential protective effect on the risk of suicide in older individuals. This warrants collaboration and enhanced awareness of suicidal behavior risks across somatic and psychiatric departments.
ISSN:17783585
09249338
DOI:10.1192/j.eurpsy.2024.1781