Zobrazit v EDS

Cat Ownership and Schizophrenia-Related Disorders and Psychotic-Like Experiences: A Systematic Review and Meta-Analysis

Uloženo v:
Podrobná bibliografie
Název: Cat Ownership and Schizophrenia-Related Disorders and Psychotic-Like Experiences: A Systematic Review and Meta-Analysis
Autoři: McGrath, John J, Lim, Carmen C W, Saha, Sukanta
Zdroj: McGrath, J J, Lim, C C W & Saha, S 2024, 'Cat Ownership and Schizophrenia-Related Disorders and Psychotic-Like Experiences : A Systematic Review and Meta-Analysis', Schizophrenia Bulletin, vol. 50, no. 3, pp. 489-495. https://doi.org/10.1093/schbul/sbad168
Informace o vydavateli: Oxford University Press (OUP), 2023.
Rok vydání: 2023
Témata: Ownership/statistics & numerical data, Ownership, schizotypy, Schizophrenia/epidemiology, Psychotic Disorders/epidemiology, Pets, 3. Good health, meta-analysis, schizophrenia, systematic review, Psychotic Disorders, 5. Gender equality, Schizophrenia, Cats, cat ownership, Humans, Animals, psychotic experiences, 10. No inequality
Popis: BackgroundIt has been proposed that cat ownership may be a risk-modifying factor for schizophrenia-related disorders and psychotic-like experiences (PLE). This study aimed to systematically review and meta-analyze publications that reported the relationship between cat ownership and schizophrenia-related outcomes.MethodologyWe searched Medline, Embase, CINAHL, Web of Science, and gray literature for publications between January 1, 1980, and May 30, 2023, regardless of geographical location and language. Backward citation search methods were used to locate additional articles. We included studies that reported original data on cat ownership and schizophrenia-related outcomes. We meta-analyzed estimates based on broad definitions (cat ownership, cat bites, and cat contact) with estimates with or without covariate adjustments. We pooled comparable estimates using random-effects models and assessed the risk of bias, heterogeneity, and study quality.ResultsWe identified 1915 studies, of which 106 were chosen for full-text review, ultimately resulting in the inclusion of 17 studies. We found an association between broadly defined cat ownership and increased odds of developing schizophrenia-related disorders. For the studies reporting unadjusted odds ratios (OR; n = 10), the pooled OR was 2.14 (95% CI: 1.29–3.55). Exclusion of one outlier study resulted in a pooled OR (n = 9) of 1.56 (95% CI: 1.27–1.92). For the studies reporting adjusted estimates (n = 5), the pooled OR was 2.44 (95% CI: 1.59–3.73). After excluding one study with suboptimal exposure/design features, the pooled adjusted OR (n = 4) was 2.40 (95% CI: 1.50–3.86). We were unable to aggregate the estimates for the PLE outcomes because of the broad range of measures.ConclusionsOur findings provide support for the hypothesis that cat exposure is associated with an increased risk of broadly defined schizophrenia-related disorders; however, the findings related to PLE as an outcome are mixed. There is a need for more high-quality studies in this field.PROSPERO registrationPROSPERO 2023 CRD42023426974. Available from: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023426974
Druh dokumentu: Article
Jazyk: English
ISSN: 1745-1701
0586-7614
DOI: 10.1093/schbul/sbad168
Přístupová URL adresa: https://pubmed.ncbi.nlm.nih.gov/38041862
Rights: OUP Standard Publication Reuse
Přístupové číslo: edsair.doi.dedup.....316a2117d7fa00abecedd0b0c8fe24bf
Databáze: OpenAIRE
Popis
Abstrakt:BackgroundIt has been proposed that cat ownership may be a risk-modifying factor for schizophrenia-related disorders and psychotic-like experiences (PLE). This study aimed to systematically review and meta-analyze publications that reported the relationship between cat ownership and schizophrenia-related outcomes.MethodologyWe searched Medline, Embase, CINAHL, Web of Science, and gray literature for publications between January 1, 1980, and May 30, 2023, regardless of geographical location and language. Backward citation search methods were used to locate additional articles. We included studies that reported original data on cat ownership and schizophrenia-related outcomes. We meta-analyzed estimates based on broad definitions (cat ownership, cat bites, and cat contact) with estimates with or without covariate adjustments. We pooled comparable estimates using random-effects models and assessed the risk of bias, heterogeneity, and study quality.ResultsWe identified 1915 studies, of which 106 were chosen for full-text review, ultimately resulting in the inclusion of 17 studies. We found an association between broadly defined cat ownership and increased odds of developing schizophrenia-related disorders. For the studies reporting unadjusted odds ratios (OR; n = 10), the pooled OR was 2.14 (95% CI: 1.29–3.55). Exclusion of one outlier study resulted in a pooled OR (n = 9) of 1.56 (95% CI: 1.27–1.92). For the studies reporting adjusted estimates (n = 5), the pooled OR was 2.44 (95% CI: 1.59–3.73). After excluding one study with suboptimal exposure/design features, the pooled adjusted OR (n = 4) was 2.40 (95% CI: 1.50–3.86). We were unable to aggregate the estimates for the PLE outcomes because of the broad range of measures.ConclusionsOur findings provide support for the hypothesis that cat exposure is associated with an increased risk of broadly defined schizophrenia-related disorders; however, the findings related to PLE as an outcome are mixed. There is a need for more high-quality studies in this field.PROSPERO registrationPROSPERO 2023 CRD42023426974. Available from: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023426974
ISSN:17451701
05867614
DOI:10.1093/schbul/sbad168